Science Flashcards

(35 cards)

1
Q

what branches off the abdominal aorta at T12

A

celiac trunk

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2
Q

what are the 3 branches of the celiac trunk

A

left gastric
splenic
common hepatic

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3
Q

which artery comes off the common hepatic and joins the left gastric (celiac trunk)

A

right gastric

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4
Q

what is the first branch of the common hepatic

A

gastroduodenal

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5
Q

when the common hepatic gives off the gastroduodenal what does it become (celiac trunk)

A

hepatic proper

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6
Q

at what level of the abdo aorta do the renal arteries branch off

A

L1

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7
Q

apart form the renal arteries, what else branches off the abdo aorta at L1

A

superior mesenteric artery

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8
Q

what branches off the abdo aorta at L2

A

gonadal arteries

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9
Q

what branches off the abdo aorta at L3

A

inferior mesenteric artery

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10
Q

at what vertebral level does the abdo aorta bifurcate into the left and right common iliacs

A

L4

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11
Q

where does the inferior mesenteric vein drain

A

splenic vein

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12
Q

when the splenic vein and superior mesenteric veins join, what do they become

A

hepatic portal vein

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13
Q

which enzyme converts glucose to glucose-6-phosphate in the glycogenesis pathway

A

hexokinase

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14
Q

where does gluconeogenesis occur (breakdown of glucose)

A

liver

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15
Q

in beta oxidation (fatty acyl coA to acetyl coA) how many ATP are produced for a fatty acid with ā€˜n’ carbons

A

ATP = 7n-6 where n=number of carbons in fatty acid

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16
Q

in the catabolism of which substance is urea made (from ammonium ions)

A

amino acid catabolism

17
Q

where are peyers patches

A

epithelium of GI tract

18
Q

main antibody in the gut

what does a deficiency in this present as

A

IgA

coeliac disease

19
Q

in the salivary glands;

where does secretion of saliva happen

where does secondary modification of saliva happen

A

acinar cells

duct cells

20
Q

which cell do parasympathetics work on to increase salivary secretion

21
Q

in the stomach, what do G cells secrete

what to D cells secrete

A

G cells = gastrin

D cells = somatostatin

22
Q

what do PPIs eg omeprazole do

what are they used for (2)

A

inhibit gastric acid secretion

gastric ulcers, GORD

23
Q

how do you treat dyspepsia

why dont you use a PPI

A

H2 receptor antagonist (eg ranitidine)

bc they do the same job, just work faster

24
Q

what is ALT specific to

when is it high in the blood

A

liver (aLt = Liver)

hepatocyte damage

25
what is AST comparable to when is it high in the blood
ALT hepatocyte (and heart and kidney) damage = non specific
26
what does AST>ALT imply
alcoholic fatty liver disease | wASTed
27
what is ALP specific to when is it high
biliary ducts gallstones, PBC, PSC, pancreatic cancer
28
when is GGT raised
alcoholic liver disease | GGT = Good Gin and Tonic
29
where is the problem if there is unconjugated bilirubin
pre hepatic (haemolytic anaemia)
30
where is the problem if there i conjugated bilirubin
hepatic or post hepatic (bile duct obstruction) jaundice
31
high amylase
pancreatitis
32
where is albumin made low albumin
liver advanced cirrhosis
33
increased prothrombin time (INR) can be caused by liver disease what other 2 things can increase INR
over coagulation | vit K deficiency
34
alcohol consumption guidelines
14 units max per week over at least 3 days (with several alcohol free days)
35
how much is 1 unit of alcohol in terms of pure alcohol
1 unit = 10ml of pure booze