Flashcards in Screening and Assessment of Genetic Disorders Deck (3)
Describe the basis of pre-implantation genetic diagnosis (PGD).
1. 1-2 cells are removed from the embryo at around 3 days, when the embryo has 6-10 cells
2. Genetic tests are carried out on the cells, including FISH, PCR, QF-PCR etc.
3. Only healthy embryos are then implanted back into the woman (up to 2 at a time)
Discuss the advantages (1) and disadvantages (4) of pre-implantation genetic diagnosis (PGD).
-Termination not necessary because all embryos are healthy
-Long waiting times
-Not available to all women
-Multiple visits and procedures needed
-Take home baby rate less than 50%