SECONDARY HEMOSTASIS Flashcards
(15 cards)
Factors involved in contact group
PK, HMWK, XI, XII
Factors involved in prothrombin/vitamin k -dependent group
Factors: 9, 10, 7, 2
Factors involved in fibrinogen group
I, V, VIII, XIII
Factors of zymogen group
IX, X, VII, II, XI, XII
Factors of cofactors
III, V, VII, HMWK, PROTEIN S
Fibrin clot precursor
Factor I - Fibrinogen
Transglutamase
XIII
Activated by the release of Factor 3 into the circulation from injured tissue
Extrinsic pathway
Factors involved in extrinsic pathway
III, VII
Activation occurs when a vessel is injured exposing the sub-empty level basement membrane and collagen
-this will lead to the activation of the contact factor
Intrinsic pathway
Factors involved in intrinsic pathway v
XII, XI, IX, VII
Clotting is the visible result of the Fibrinogen conversion to fibrin stabilize cloth
Common pathway
Fibrin formation occurs in three phases
-proteolysis
-polymerization
-stabilization
Is an insoluble gel
Fibrin