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PCOL 1 > Selective B-2 until Sympathomimetics > Flashcards

Selective B-2 until Sympathomimetics Flashcards

1
Q

Examples of Short Acting Selective B-2 Agonists

A

Salbutamol
Terbutaline

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2
Q

Examples of Long Acting Selective B-2 Agonists

A

Formoterol
Salmeterol
Indacaterol
Pirbuterol

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3
Q

Indications of Selective B-2 Agonist

A

Bronchial Asthma

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4
Q

Used for treatment of asthma exacerbations

A

SABA (Short Acting Beta-2 Agonists)

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5
Q

Used for prevention of Bronchial Asthma

A

LABA (Long Acting Beta-2 Agonists)

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6
Q

Examples of Tocolytics

A

Isoxsuprine
Terbutaline
Ritodrine

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7
Q

Indications for Tocolytics

A

Premature labor
- labore before 37th week of gestation

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8
Q

Example of Selective D-1 Agonist

A

Fenoldopam

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9
Q

Indications for Fenoldopam

A

Alternative in the management of hypertension

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10
Q

Examples of Selective D-2 Agonist

A

Levodopa
Cabergoline
Bromocriptine

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11
Q

Indication for Levodopa

A

Parkinson’s Disease

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12
Q

Indication for Cabergoline & Bromocriptine

A

Hyperprolactinemia

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13
Q

Produced in high concentration in protein-rich foods by decarboxylation of tyrosine during fermentation

A

Tyramine

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14
Q

How does sympathomimetics work?

A

stimulate the release of catecholamines from neurons

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15
Q

What is Catecholamine reuptake inhibition

A

inhibition of catecholamine reuptake which increases concentrations of neurotransmitters ready for receptor binding

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16
Q

Examples of Norepinephrine Reuptake Inhibitors (NARIs)

A

Reboxetine
Atomexetine

Antidepressants are included here

17
Q

What does cocaine do?

A

inhibit dopamine reuptake in the pleasure centers of the brain

18
Q

What does Monoamine Oxidase Inhibitors (MAOIs) do?

A

inhibit the enzymes responsible for catecholamine degradation

Indication (depression)

19
Q

Mechanism of action for Ephedrine & Pseudoephedrine

A

Agonistic effects on adrenoreceptors

Increase the release of catecholamines

20
Q

Indications for mixed-acting sympathomimetics

A

Nasal congestion

Bronchial asthma

21
Q

Adverse effects of Mixed-Acting sympathomimetics

A

Tachycardia
Hypertension
Urinary Retention

PCOL 1 (10 decks)

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