Semana 4 - Inmunidad Flashcards

(20 cards)

1
Q

is classically found on the surface of natural killer cells?

A
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2
Q

La inmunidad innate tiene memoria. VERDADERO O FALSO

A

FALSO. La respuesta futura es igual a la inicial

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3
Q

A high band cell count would suggest

A

Infection

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4
Q

Forma del núcleo de los monocitos

A

Tiene forma de herradura

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5
Q

En donde se encuentran las células T en el nodo linfático?

A

Paracorteza

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6
Q

Qué permite que los receptores de la célula T se unan específicamente a un antígeno presentado?

A

La recombinación VDJ

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7
Q

Qué activa a una célula T naive que se encuentra en la paracorteza de un nodo linfñatico?

A

Unirse a un antígeno

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8
Q

Función del coreceptor CD40/CD40L

A

Permite a la célula T mandar señal a célula B para convertirse en una célula plasmática, producir anticuerpos y cambiar de clase de anticuerpo

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9
Q

Cuando se hace cambio de clase de un anticuerpo, qué parte del anticuerpo se necesita cambiar?

A

La cadena pesada

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10
Q

Un anticuerpo demuestra que…

A

Ya fuiste expuesto a cierto antígeno

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11
Q

MHC I se une a células T…

A

CD8 (Citotóxicas)

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12
Q

MHC II se une a células T…

A

CD4+ (T-helper)

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13
Q

Las células presentadoras de antígeno con MHC I se caracterizan por que…

A

Se sacrifican a sí mismas. Dado que presentan antígenos de patógenos intracelulares, las CD8+ matan completamente a estas celulas presentadoras

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14
Q

Ejemplo de pathogen recognition receptor (PRR)

A

TLR

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15
Q

Anticuerpo clásico que demuestra que ya hubo exposición a patógeno anteriormente

A

IgG

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16
Q

Células presentadoras de antígeno

A

Macrófagos, monocitos, células dendríticas y células b

17
Q

Función primaria de del complejo mayor de histocompatibilidad

A

la presentación de antígeno a las células T naive

18
Q

Sitio en donde ocurre la activación de las células T naive gracias a las células presentadoras de antígeno?

A

Nodos linfáticos

19
Q

A patient undergoes antibody testing as part of a research study. Bloodwork showed elevated levels of IgG against COVID-19 and non-detectable levels of IgM. Which of the following is the most likely conclusion?

A

La persona tiene memoria inmunológica contra COVID-19

*Compared to IgM, IgG antibodies are detectable for longer periods of time (weeks to months) following antigen exposure. In serum testing, IgG antibodies are often measured to determine if previous exposure to a certain pathogen has occurred.

20
Q

An 8-year-old girl eats a cookie and minutes later develops hives and difficulty breathing. Which cells are most likely to be mediating this reaction?

A

Mastocitos

*Mast cells are the main cellular drivers of allergic reactions, including anaphylaxis. Basophils can also contribute to allergic reactions, albeit to a lesser extent.