Sepsis 6 Flashcards
(30 cards)
what is sepsis?
life-threatening organ dysfunction caused by a dysregulated host response to infection
what is septic shock?
circulatory and cellular/ metabolic dysfunction
presence of sepsis + persistent hypotension <65mmHg and a lactate >2mmol/L
what can a simple infection lead to?
sepsis > septic shock
can you have sepsis without an infection?
no
what is infection?
invasion and multiplication of microorganisms in the body
causes of infection
bacteria
viruses
fungi
parasites
two types of infection
- localised e.g. abscess
2. disseminated e.g. bacteraemia
do some bacteria live locally?
yes and cause no damage
what is include in the sepsis 6?
- oxygen
- fluid resuscitation
- blood cultures
- IV antibiotics
- lactate
- UO
when should sepsis 6 be done?
within 1 hour of suspected sepsis in a patient
when should oxygen be given?
saturations below 94%
what fluid resuscitation is given?
0.9% saline IV as 500mls bolus
what blood cultures are taken?
one culture is enough
what blood cultures are taken if endocarditis is suspected?
3 within 1 hour before antibiotics (Duke’s criteria)
are blood cultures taken before IV antibiotics in sepsis 6?
no
when should you start IV antibiotics in sepsis?
immediately
how do you decide which prophylaxis antibiotics to use?
site
PMH
RF
what do large abscesses need?
drainage as no blood supply so antibiotics do not target well
what does a high lactate indicate?
hypoperfusion
what is the sepsis 6 referred to as?
take 3
give 3
what should you do in hours 2-6 of a septic patient?
- continue resuscitation= MAP >65 and UO >0.5ml/kg/hr
- regular review
- improve NEWS
- haemodynamically stable
- reduce lactate
scoring systems for sepsis
SEWS SIRS SOFA qSOFA NEWS
what is SIRS
systemic inflammatory response system
no longer used
what is SOFA?
scoring system that is too long winded so have been shortened to qSOFA
