Sepsis

Question 1

Quais os critérios de síndrome de resposta inflamatória sistémica (SIRS)? (4)

Answer 1

São necessários 2 (dos quais 1 a febre ou leucocitose):

1. Core temperature of >38.5°C or <36°C
2. Tachycardia, or for children younger than one year of age, bradycardia
3. Mean respiratory rate more than two standard deviations above normal for age or mechanical ventilation
4. Leukocyte count elevated or depressed for age, or >10 percent immature neutrophils

Question 2

Qual a definição de sepsis grave?

Answer 2

associated with cardiovascular dysfunction, acute respiratory distress syndrome (ARDS), or dysfunction in two or more other organ systems

Question 3

Qual a definição de choque séptico?

Answer 3

sepsis with cardiovascular dysfunction that persists despite the administration of ≥40 mL/kg of isotonic fluid in one hour

Question 4

Qual a definição de choque séptico refractário?

Answer 4

1. fluid-refractory septic shock exists when cardiovascular dysfunction persists despite at least 60 mL/kg of fluid resuscitation
2. catecholamine-resistant septic shock exists when shock persists despite therapy with dopamine ≥10 mcg/kg/min and/or direct-acting catecholamines