Sepsis - Definition, Signs and Symptoms Flashcards Preview

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Flashcards in Sepsis - Definition, Signs and Symptoms Deck (11)
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1

What is the definition of sepsis

Sepsis is a life-threatening organ dysfunction due to a dysregulated host response to infection

2

What clinical criteria differentiates sepsis from infection

Organ dysfunction

3

Why is sepsis associated with infection

Although it is not an infection, it doesn’t occur in the absence of infection
It is triggered by infection

4

What is septic shock

Sepsis with persisting hypotension that requires vasopressore to maintain the mean arterial pressure at >65mmHg and with a serum lactate concentration >2moll-1

5

What is qSOFA

A tool to clinically characterise patients at risk of sepsis

6

What would score 1 using the quick SOFA criteria

Elevated respiratory rate
Score of 14 on Glasgow Coma Scale
Pre-existing and poorly controlled diabetes

7

What would score 2 using the quick SOFA criteria

Organ dysfunction

8

What are common causes of sepsis

Small cut in the skin
Meningitis
Kidney infection
Throat infection
Coronavirus
Urinary tract infection

9

What are common sources of infection that trigger sepsis

Gram positive bacteria - Staph aureus
Gram negative bacteria
Fungal - candida

10

Where is sepsis most prevalent

US - 65% of cases

11

What patients are most likely to get sepsis

Medically and immune-compromised patients:
Cancer
Cirrhosis
Autoimmunity
HIV/AIDS
Organ transplantation
Diabetes