Seronegative Inflammatory Arthritis Flashcards Preview

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Flashcards in Seronegative Inflammatory Arthritis Deck (15)
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1
Q

rheumatoid arthritis is 70%-80% seropositive for what

A

rheumatoid factor and

anti-CCP antibodies

2
Q

what is spondyloarthritis

A

it is an umbrella term for inflammatory diseases that affect entheses and joints,
Involvement of the sacroiliac joints and spine
– Sometimes with an oligoarticular peripheral arthritis

3
Q

give two examples of acial SpA

A

Ankylosing spondylitis

– Non radiographic axial SpA

4
Q

give four examples of periphial SpA

A

Psoriatic Arthritis
– Enteropathic Arthritis
– Reactive Arthritis
– Juvenile onset SpA

5
Q

an individual has morning stiffness for longer than 30 mins, peripheral arthritis, enthesitis, dactylitis, night pain, buttock hip neck pain and chronic low back pain, improves with excercise, what is this likely to be

A

Axial Spondyloarthritis (AxSpA)

6
Q

what are the symptoms of AxSpA

A
Symptoms
– Chronic low back pain
– Buttock/hip/ neck pain
– Improves with exercise
– Night pain
– Morning stiffness >30 mins
– Peripheral arthritis
– Enthesitis
– Dactylitis
7
Q

what age of does AxSpa tend to affect and gender

A

age 20-40 affects men more than women

8
Q

how do you manage someone with axial SpA

A

Nsaids, excercise and BASDAI on two occasions 12 weeks apart

9
Q

what does BASDAI stand for

A

Bath Ankylosing Spondylitis Disease Activity Index is a validated diagnostic test which allows a physician, usually a rheumatologist, to determine the effectiveness of a current drug therapy, or the need to institute a new drug therapy for the treatment of Ankylosing spondylitis (AS).

10
Q

what are the Clinical Features of PsA

A
Peripheral arthritis
• Axial disease
• Enthesitis
• Dactylitis
• Skin and nail disease!!
11
Q

if PsA is polyarticular describe what areas are involved

A

Involvement of many small joints usually in hands and feet
– Most common type >50%
– Rarely get rapid joint damage (Arthritis mutilans)

12
Q

if PsA is oligoarticular describe what areas are involved

A

– Affects a few large joints

– Eg knee, ankle, elbow

13
Q

appreciate Psoriatic Arthritis: Nail Changes which are..

A

yellowing, pitting etc

14
Q

what is Asymmetric oligoarthritis

A

his type of psoriatic arthritis affects fewer than five small or large joints in the body but does not necessarily occur on both sides of the body. (For example, a person might experience joint pain in one elbow but not the other.

15
Q

what is arthritis mutilans

A

Arthritis mutilans is a rare medical condition involving severe inflammation damaging the joints of the hands and feet, and resulting in deformation and problems with moving the affected areas; it can also affect the spine.