Serotonin syndrome Flashcards
1
Q
give four causes of serotonin syndrome
A
monoamine oxidase inhibitors
SSRIs
ecstasy
amphetamines
2
Q
give the three cardinal features of serotonin syndrome
A
neuromuscular excitation
autonomic nervous system excition
altered mental state
3
Q
describe CK values seen in serotonin syndrome vs neuroleptic malignant syndrome
A
seen in both
more associated with neuroleptic malignant syndrome
4
Q
how do you manage severe serotonin syndrome
A
chlorpromazine/cyproheptadine
5
Q
how do you manage neuroleptic malignant syndrome
A
dantrolene
6
Q
describe the differences in onset between serotonin syndrome and neuroleptic malignant syndrome
A
SS: fast onset (hours)
NMS: slower onset (hours-days)
7
Q
describe the pupils in both
A
SS: dilated
NMS: normal
8
Q
describe the reflexes in both
A
SS: increase
NSM: decreased
