Flashcards in Serum tumor markers Deck (10):
-Metastases to bone or liver
-Paget disease of bone
-seminoma (placental ALP).
-yolk sac (endodermal sinus) tumor
-mixed germ cell tumor
*High levels associated with neural tube and abdominal wall defects
*low levels associated with Down syndrome.
*Hydatidiform moles and *Choriocarcinomas
(*Gestational trophoblastic disease)
-mixed germ cell tumor.
CA 15-3/CA 27-29
Medullary thyroid carcinoma
Very nonspecific but produced by ∼ 70% of colorectal and
also produced by gastric,
breast, and medullary thyroid carcinomas
Can also be elevated in BPH and prostatitis
Questionable risk/benefit for screening.