Session 1 Flashcards

1
Q

What does digestion do?

A

Convert food to a sterile, neutral and isotonic solution that is ready for absorption

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2
Q

How is food processed to become small molecules?

A

First it is physically broken down in the act of Mastication to release large molecules. Then it is broken down chemically to release small molecules

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3
Q

What is Mastication?

A

Chewing

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4
Q

What does Saliva do?

A

Protects the mouth
Lubricates food
Starts digestion

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5
Q

What properties of Saliva help it protect the mouth?

A

Wet to keep the mucosa alive

High Ca2+ and alkaline to protect the teeth

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6
Q

What is a Bolus?

A

A ball of food that is streamlined ready to be swallowed

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7
Q

Where does water added to the food come from in the Duodenum?

A

Extra Cellular Fluid

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8
Q

Where does Bile added to the food come from in the Duodenum?

A

From the Liver and Panreas

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9
Q

What adaptations does the small intestine have to absorb the nutrients/fluid from food?

A

A brush border to greatly increase the surface area

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10
Q

How does the small intestine absorb nutrients?

A

The epithelium absorb small molecules using transport coupled with Na+ absorption.

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11
Q

Where do all absorbed nutrients go from the small intestine?

A

To the hepatic portal circulation

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12
Q

Why is transit in the large intestine slow?

A

To ensure there is maximum amount of time to absorb the last nutrients and water

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13
Q

How can the GI system cause dehydration?

A

A slight imbalance between secretion and absorption will lead to a loss of water and electrolytes from bodily fluids. eg Diarrhoea

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14
Q

What controls the GI system?

A

Neural system
Paracrine system
Endocrine system
Unusual has all 3 controls that overlap

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15
Q

What usually causes GI issues?

A

The control systems going wrong. Hard to treat due to the 2 systems overlapping

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16
Q

What neural systems are involved in GI control?

A

Somatic nervous system for ingestion and excretion

Autonomic nervous system controls the rest - Parasympathetic mostly. Has more than Ach as neurotransmitters

17
Q

What transmitters are involved in the paracrine control?

A

Histamine and prostaglandins in the stomach

Other vaso active substances

18
Q

What do prostaglandins do in the stomach?

A

They control the defenses of the stomach against stomach acid

19
Q

What are the hormones that help the endocrine control?

A

Range of hormones, but all polypeptides and 2 families. It is important to appreciate the relationship between the 2 families for function