session2

Question 1

Beta-lactam antibiotics

Answer 1

penicillins and cephalosorins

Question 2

cephalosporin is —————type of antibiotic?

Answer 2

beta lactam

Question 3

Tetracyclines

Answer 3

tetracycline, oxytetracycline, demeclocycline, lymecycline, doxycycline and minocycline. Tigelcycline

Question 4

Rifamycins (Ansamycin)

Answer 4

Rifampin , rifadin , rifabutin, and rifapentine

Question 5

a group of structurally similar macrocyclic antibiotics, which are firstline oral agents for tuberculosis.?

Answer 5

rafimycins

Question 6

The aminoglycosides

Answer 6

streptomycin, gentamicin, kanamycin

Question 7

what the type of gemtomysin

Answer 7

it is aminoglycosides

Question 8

chemical structure of the macrolids contain

Answer 8

macrocyclic lacton ring

Question 9

Macrolides

Answer 9

erythromycin, clarithromycin and azithromycin

Question 10

Cyclic lipopeptide

Answer 10

bacitracin, polymyxin and Daptomycin

Question 11

bacitracin is one of the important antibiotics which type of antibiotc is belong —?

Answer 11

cyclic lipopeptide

Question 12

Amphenicols (Phenicols) exmple?

Answer 12

chloramphenicol

Question 13

lincomycin belong to —–group of antibiotics

Answer 13

Lincsamides

Question 14

lincsamide contain

Answer 14

clindamycin, pirlimycin, linsamides

Question 15

Quinolones (fluoroquinolones

Answer 15

ciprofloxacin, ofloxacin, norfloxacin, levofloxacin and moxifloxacin

Question 16

Glycopeptides ?

Answer 16

Vancomycin and teicoplanin

Question 17

Fosmycins are used mainly for ?

Answer 17

UTI

Question 18

the treatment of urinary tract infections in patients who have allergies and/or intolerance to sulfonamides and β lactams.

Answer 18

Nitrofurans

Question 19

tetracycline, chloramphenicol) ARE bacteriocidal or bacteriostatic

Answer 19

they are bacteriostatic

Question 20

chloramphenicol is bacteriostatic for ——-and bateriacidal for ———

Answer 20

gram-negative , the pnemococci

Question 21

exmple
broad specrum antibiotics
narrow spectrum antibiotic

Answer 21

tetracycline—broad-spectrum–use for gram-negative and atypical bacteria

vancomycin—–use for the gram positive cocci –namely streptococci and the enterobacteria–it is a narrow antibacterial agent

Question 22

the feature of the antibiotics

Answer 22

-selelctive toxocity
-reach to the site of action
-admistrition of the antibiotcs
-the long half life
-low or few advese effects
not interfece with other drugs

Question 23

Penicillin USE AGANIST —-

Answer 23

mainly active against streptococci

Question 24

Amoxicillin

Answer 24

streptococci and gram negative bacteria

Question 25

Flucloxacillin

Answer 25

Active against staphylococci and | Streptococci

Question 26

give exmaples on the pencilins

Answer 26

``` Penicillin: • Amoxicillin: • Flucloxacillin: • Β-lactamase inhibitor combinations: Co-amoxiclavoran – Piperacillin/tazobactam ```

Question 27

Cephalosporins use aginst

Answer 27

broad-spectrum but no anaerobe | activity

Question 28

drug belong to cephalosporin has good activity in the | CSF?

Answer 28

Ceftriaxone

Question 29

Carbapenems define

Answer 29

Carbapenems are synthetic β-lactam antibiotics that differ in structure from the penicillins

Question 30

carbipenems examples

Answer 30

 Imipenem, meropenem, doripenem, and ertapenem

Question 31

spectrum \ carbapenem

Answer 31

Very broad spectrum (including anaerobes) – Active against most (not all) Gram negative – Generally safe in penicillin allergy

Question 32

Vancomycin belong to

Answer 32

glycopeptide antibiotics use aganst the broad specturm specially aganist the multiple resistance bacteria

Question 33

antibiotic - associated colitis caused by Clostridium difficile or staphylococci which the best treatment for the patient

Answer 33

vancomysin

Question 34

spectrum of vancomysin

Answer 34

Active against most Gram positive (not G. negatives) | – Some enterococci resistant (VRE

Question 35

Tetracycline

Answer 35

Broad-spectrum but specific use in penicillin allergy, usually for Gram positive it is alos active aganist the atypical pathogens of the

Question 36

the antibioitc group are nephrotoxic

Answer 36

aminoglycoside

Question 37

spectrum of the aminoglycoside

Answer 37

the negative gram bacteria'

Question 38

main uses = aminoglycoside

Answer 38

severe sepsis

Question 39

examples on Macrolides

Answer 39

erythromycin (& clarithromycin)

Question 40

macroilids uses

Answer 40

• Alternative to penicillin for mild Gram positive infections Also active against atypical respiratory Pathogens

Question 41

ciprofloxacin

Answer 41

it is belong to quinolone that inhibit the DNA gyrase

Question 42

spectrum of the cripoflaxon

Answer 42

Very active against Gram negatives | • Also active against atypical pathogens

Question 43

Metronidazole

Answer 43

``` Active against anaerobic bacteria – Also active against protozoa: – Amoebae (dysentery & systemic) – Giardia (diarrhoea) – Trichomonas (vaginitis ```

Question 44

Aciclovir is antiviral use aganist

Answer 44

Herpes simplex – genital herpes, encephalitis | – Varicella zoster – chicken pox & shingles

Question 45

Oseltamivir

Answer 45

Influenza A & B

Question 46

examples of the b-lactmase inh8bitprs

Answer 46

clavulanic acid and aublbacetam and tazobactan