Setting the scene- Anatomy Flashcards

1
Q

What are the 4 layers of the gut tube?

A

Muscosa

Submycosa

External muscle layers

Serosa

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2
Q

What is mucosa made of?

A

Epothelium

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3
Q

What does the Mucosa do?

A

Selectively permeable barrier

Facilitate transport and digestion of food

Produce absorption

Produce hormones

Produce mucus

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4
Q

What does the lamina propria do?

A

Produce lots of lymphoid nodules and macrophages

Produces antibodies e.g. IgA to protect against bacteria and viral invasion

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5
Q

What is muscularis mucosae?

A

Layers of smooth muscle oriented in different directions

keeps epithelium in contact with gut contents

helps keep crypy contents dynamic

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6
Q

What does the submucosa contain?

A

Dense connective tissue, blood vessels, glands, lymphoid tissues

Submucosal plexus (Meissners)

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7
Q

What does the inner circle muscle contain?

A

Myesnteric plexus

outerlongitudinal muscle

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8
Q

What is within the serosa??

A

Blood, lymph vessels and lympohid tissue

continuous messeteries

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9
Q

Where is there stratified squamous epithelia?

A

Oesphagus and distal anus

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10
Q

Apart from the oesphagus and anus, what is the epithelia in the rest of the gut?

A

simple columnar

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11
Q

What is an enterocyte?

A

Simple columnar cell that absorbs

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12
Q

Where are enterocytes?

A

small intestine and colon- 1 cell thick

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13
Q

What do enterocytes have to transport nutrients through?

A

Apical membrane

basolateral membrane

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14
Q

What are special features of enterocytes?

A

Microvilli

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15
Q

Where are goblet cells?

A

Scattered between enterocytes

increasing in number from duodenum to colon

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16
Q

What do goblet cells do?

A

produce mucus

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17
Q

What does mucus protect epithelia from?

A

Friction

Chemical damage

Bacterial inflammation

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18
Q

What are gastric surface mucous cells?

A

Line the gastric mucosa

Secrete mucus that froms barrier to stomach acid

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19
Q

What creates a large surface area in the gut tube?

A

Permanent folds

villi

microvilli

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20
Q

What are rugae?

A

temporary folds in the stomach

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21
Q

Where are villi?

A

Small intestine

Not in colon

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22
Q

Where are crypts?

A

In small and large intestine

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23
Q

What do crypts contain?

A

Stem cells

Paneth cells

Eneroendocrine cells

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24
Q

Why are there stem cells in the crypts?

A

Constantly divide to replace epithelia

25
What are peneth cells?
secrete antibacterial proteins to protect stem cells
26
What do enteroendocrine cells do?
Secrete hormones that control the function of the gut
27
What horomes do enteroendocrine cells release in the crypts?
Gastrin cholecytokinin secretin
28
What problems can occur with the crypts?
Inflammatory bowel disease- crypts alteration, cryptitis, crypt abcess
29
30
What exocrine glandular tissue is in the gut?
Organised secretory cells- acini, tubules e.g. salviary gland, pancreas and brunners glands
31
What do acini tend to secrete?
Serous secretion and enzymes
32
What do tubules secrete?
mucous
33
What can salivary glands secrete?
Serous and mucous
34
What can cause ulceration?
Erosion of musculararis mucosae Failure of protective mechanism e.g. mucus production
35
What is coeliac disease?
inability to tolerate gliandin damages mucosa so poor digestion and malabsorption
36
What are the 3 anterolateral muscles?
External oblique Internal oblique Transverse abdominis
37
What are the layers of the abdominal wall?
Skin Fascia fat external oblique internal oblique transverse abdominis rectus abdominis transversalis fascia peritoneum
38
What is an aponeurosis?
thin sheet like tendon
39
What does the aponeurosis of the lateral muscles surround?
Rectus abdominis
40
What is the arcuate line?
Lower limit of the posterior layer of the rectus sheath inferior epigastric vells pierce rectus abdominus Half way between umbilicus and pubic crest
41
What is mesentery?
A double fold of peritoneum that attaces certain viscera to the posterior abdominal wall
42
What has a mesentery?
Jejenum ilieum appendix transverse colon, sigmoid colon rectum
43
What does mesenterycontain?
Blood vessels lymph vessels nerves fat
44
What is a peritoneal ligament?
A double fold of peritoneum that connects two viscera together or viscera to abdominal wall
45
What are 4 examples of peritoneal ligaments?
Gastrocolic ligament- stomach to transverse colon Gastrosplenic ligament- stomach to spleen Falciform ligament- liver to abdominal wall Triangular ligament- liver to diaphragm
46
What is an omenta?
Double fold of peritoneum
47
Where is the greater omenta?
hangs down off the greater curve of the stomach
48
Where is the lesser omenta?
connects lesser curve of stomach to liver
49
What is a spincters purpose?
Divide into sections control movement along the tube prevent reflux of material
50
Where are there sphincters?
Upper oesophageal Lower oesophageal pyloric sphincter ileo-caecal anal internal and external
51
Which spincter is voluntary?
external anal
52
What is this?
Mesentery
53
What is this?
Omenta
54
What is the blood supply for the foregut?
Coeliac trunk
55
What is the blood supply for the mid gut?
SMA
56
What is the blood supply for the hind gut?
Inferior mesenteric artery
57
Where does venous drainage go to from the gut?
Liver via the portal vein
58
What is a portal system?
‘a vascular arrangement in which blood from the capillaries of one organ is transported to the capillaries of another organ by a connecting vein or veins’
59
What does the blood supply for the gut come from?
Abdominal aorta