Sevoflurane

Question 0

No more than __ carbon atoms, non flammable, and stable to soda lime

Answer 0

Four

Question 1

Is sevo a methyl isopropyl ether or a methyl ethyl ether?

Answer 1

Methyl isopropyl ether

Question 2

Fully halogenated compounds are usually __ anesthetics and convulsants

Answer 2

Poor

Question 3

Metabolism rate of sevo

Answer 3

3-5%

Question 4

Blood gas partition coefficient of sevo

Answer 4

0.69

Question 5

Sevo is __ an airway irritant

Answer 5

Not really

Can do a one breath sevo induction

Question 6

How many fluorine atoms on sevo?

Answer 6

Seven

Question 7

Des is synthesized from __

Answer 7

ISO

Question 8

Mac of sevo

Answer 8

2.1%

Question 9

Addition of nitrous __ mac of sevo

Answer 9

Decreases

Question 10

Mac awake __

Answer 10

0.3 x mac (2.1)

Question 11

Mac BAR

Answer 11

1.5x mac

Question 12

Mac intubation

Answer 12

2x mac

Question 13

Hypothermia, increased age, benzo, opiates, alpha2 agonists, nitrous, pregnancy, acute ethanol, sick, hypoNA, hyperMag
All __ mac

Answer 13

Decrease

Question 14

CNS catecholamine stim, chronic ethanol, hyperNa

All __ mac

Answer 14

Increase

Question 15

The lower the BGPC, the __ alveolar conc equilibrates to arterial conc

Answer 15

Quicker

Question 16

Low solubility of sevo facilitates __ lung elimination

Answer 16

Rapid

Question 17

Sevo vapor pressure

Answer 17

160 mmHg

Question 18

Increased ventilation = __ equilibration

Answer 18

Quicker

Question 19

Increased cardiac output = __ equilibration

Answer 19

Slower

Question 20

Sevo could equilibrate in __ minutes in the vessel rich group

Answer 20

4-8

Question 21

Can sevo provide retrograde amnesia or long term impairment of intellectual function?

Answer 21

NO

Question 22

Sevo __ reduce cerebral metabolic oxygen requirements

Answer 22

Will

Question 23

Sevo has the potential to increase ICP in patients with space occupying lesions not receiving hyperventilation.

Answer 23

Slide 37
It is a cerebral blood vessel dilator
Treat by hyperventilate to end tidal CO2 around 30

Question 24

Around 2 mac you may have an __ EEG

Answer 24

Isoelectric

Question 25

Sevo does not produce seizures and can actually __ seizure activity

Answer 25

Suppress

Question 26

Sevo increases cerebral blood flow for up to __ hours

Answer 26

Four

Question 27

Hyperventilate to an end tidal CO2 of __ to counteract increased cerebral blow flow

Answer 27

30

Question 28

Sevo iso des ALL lower BP by decreasing __

Answer 28

SVR

Question 29

Sevo __ delivery of NMB

Answer 29

Enhances

Question 30

Sevo and right to left shunt?

Answer 30

Yes

Question 31

Sevo has __ effect on PVR

Answer 31

No

Question 32

Spontaneous ventilation causes CO, SBP, and SVR to __ more, but HR will increase more

Answer 32

Decrease

Question 33

Can you abruptly change concentrations in sevo?

Answer 33

Yes, unlike iso and des

Question 34

Inhalation induction with a sick heart?

Answer 34

NO

Question 35

Sevo causes apnea around

Answer 35

1.5-2 mac

Question 36

Sevo breathing is like a lizard on a hot rock

Answer 36

Small tidal, fast rate, decreased minute ventilation, increased CO2

Question 37

The ventilatory effects __ over time

Answer 37

Decrease

Question 38

Does sevo have muscle relaxant properties?

Answer 38

Yes, weak

Question 39

__ is the best way to counteract the ventilatory effects of sevo

Answer 39

Put a garden hose down their gullet

Question 40

Sevo is a __ bronchodilator and can break an attack of status asthmaticus

Answer 40

Potent

Question 41

Where is sevo metabolized?

Answer 41

Liver by cytochrome p450

Question 42

If your patient has a hx of post anesthesia hepatitis, that cannot occur with use of __ ONLY SEVO cannot be implicated in post-anesthetic hepatotoxicity.

Answer 42

Sevo

Question 43

What is a byproduct of sevo metabolism that is nephrotoxic?

Answer 43

Free fluoride

Question 44

Two bad compounds that sevo can metabolized into?

Answer 44

Compound A | HFIP

Question 45

Amsorb produces the lowest concentration of compound _

Answer 45

A | Test question

Question 46

Keep sevo __ during obstetrics due to uterine atony and possible hemorrhage

Answer 46

Minimal