SFP: skin I

Question 1

What are the layers of the epidermis from most external to most deep?

Answer 1

Stratum corneum, stratum granulosum, stratum spinosum, stratum basale

Question 2

What may melanophages mean in a sample?

Answer 2

Hyper or hypopigmentation

Question 3

What is orthokeratosis?

Answer 3

Thickened cornified layer without retention of nuclei

Question 4

What is parakeratosis?

Answer 4

Thickened cornified layer with retention of nuclei; this is never normal.

Question 5

What might hyperkeratosis look like clinically?

Answer 5

Scaly rashes

Question 6

What is acanthosis?

Answer 6

Epidermal hyperplasia

Question 7

What is papillomatosis?

Answer 7

Surface elevation (bumpiness) caused by hyperplasia and enlargement of dermal papilla

Question 8

What is spongiosis?

Answer 8

Intracellular edema in the epidermis

Question 9

What is acantholysis?

Answer 9

Lysis or disruption of intercellular adhesive junctions between keratinocytes

Question 10

What is dyskeratosis?

Answer 10

Abnormal, premature keratinization in the epidermis. Cells get really pink, and nuclei get super small.

Question 11

What is exocytosis in the skin?

Answer 11

Lymphocytes migrating to the epidermis

Question 12

Are scars rooted in the dermis or epidermis?

Answer 12

Dermis

Question 13

What is a keloid?

Answer 13

A reparative reaction in the dermis that goes overboard.

Question 14

What structures are no longer present in scars?

Answer 14

Adnexal structures

Question 15

What is panniculitis?

Answer 15

Inflammation of subcutaneous tissue

Question 16

What is a macule?

Answer 16

A circumscribed, flat lesion less than 5 mm

Question 17

What is a patch?

Answer 17

A circumscribed, flat lesion greater than 5 mm

Question 18

What is a papule?

Answer 18

An elevated/dome-shaped lesion less than 5 mm

Question 19

What is a nodule?

Answer 19

An elevated/dome-shaped lesion greater than 5 mm

Question 20

What is a plaque?

Answer 20

An elevated, flat-topped lesion greater than 5 mm

Question 21

What is a vesicle?

Answer 21

A fluid-filled blister less than 5 mm

Question 22

What is a bulla?

Answer 22

A fluid-filled blister greater than 5 mm

Question 23

What is a pustule?

Answer 23

Raised, discrete, pus-filled lesions

Question 24

What is a wheal?

Answer 24

An itchy, elevated lesion with blanching erythema

Question 25

What is an erosion?

Answer 25

Loss of a portion of the entire epidermis; it will heal without scar

Question 26

What is an ulcer?

Answer 26

Loss of the epidermis and a portion of the dermis; it will result in a scar

Question 27

What is an excoriation?

Answer 27

A self-inflicted break in the skin from scratching

Question 28

What is lichenification?

Answer 28

Thickened, rough skin due to repeated rubbing or scratching

Question 29

What is crust?

Answer 29

Dried serum, pus, blood, and epithelial debris

Question 30

What is a scale?

Answer 30

A plate-like mass of keratin due to abnormal keratinization. Could be coarse, white, yellow, dry, etc. presents with hyperkeratosis microscopically