Flashcards in SH9: Microbial pathogenesis Deck (11)
What is Pathology
Study of diseases -progress, causes, treatment
What is Medical microbiology
Pathology of infectious diseases, caused by microorganisms, capable of being transmitted
What are parasites?
What is Virulence?
Ability of an organism to cause disease
What are pathogens?
Microorganisms that cause disease
What are opportunistic pathogens
Do not normally cause disease, and may be common in our bodies and are harmless (E. coli- lives harmlessly in GI tract, but causes infections if moved to the urinary tract) but may live in a host, but can cause disease under some circumstances. Also, can be an issue in those using immunosuppressant’s.
What are obligate pathogens
evolved virulence factors (toxins) that cause disease, so cause disease as part of their life cycle. HIV causes AIDS and reduces the immunological defence of a host body.
What are biofilms
Mixed communities of microorganisms. they are a mucilaginous surface community, they form on and in the human body (when you don’t brush your teeth). Biofilms can form on damage tissue, and infect the body, causes disease- they are difficult to treat.
Transmission of disease from infected to non-infected host:
• Aerosols; coughing or sneezing (whooping cough)
• Faecal-oral; faeces by water or food (Norwalk virus)
• Vector-borne; by insects either externally or internally (malaria)
• Body contact
• Breast feeding
• EBV –epstein barr virus
• Sexually transmitted disease
• Vertical transmission; the spreading from parent to child
What is needed in order to cause disease?
Transmission is not sufficient to cause disease, pathogen need to breach the hosts’ defence mechanisms (immune system).