Shock Flashcards

1
Q

Goals of primary assessment in shock?

A

Provide oxygen
Substitute hypovolemia
Identify life-threatening causes

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2
Q

What effects in shock are caused by sympathetic stimulation?

A
Tachycardia
Sweating
Pallor (reduced skin perfusion)
Thready pulse (reduced pulse pressure)
Ileus (reduced gut perfusion)
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3
Q

Why does plasma lactate rise in a shocked patient?

A

Oxygen dept due to insufficient oxygen delivery to tissues increases anaerob metabolism.

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4
Q

What mechanisms can lead to insufficient oxygen delivery?

A
Decreased oxygen uptake in lungs
Reduced venous return 
Impaired cardiac function
Reduced arterial tone
Impaired organ autoregulation
Decreaded oxygen uptake and use by tissues
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5
Q

What causes are there to hypovolemic shock?

A

Bleeding: GI or ruptured aorta
Plasma: Diarrea/vomiting, diabetes, osmotisk diures, pankreatit, hyponatremi och glukokortikoidbrist, fistlar, brännskador

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6
Q

What drugs can make an apparent hypovolemia?

A

Venodilators such as nitrates, opioids, loopdiuretics

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7
Q

What happens to pulse and blood pressure in grade II shock? How much volume loss does it indicate?

A

Pulse rises (>100)
Diastolic pressure rises to narrow pulse pressure
Indicates loss of 0,75-1 L (15-30% av blodvolymen)

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8
Q

In what grade of shock does the blood pressure fall?

A

grade III

Indicates loss of 30-40% of blood volume

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9
Q

name pitfalls in shock responser

A
elderly
athletes
drugs
Pregnancy
tissue damage
hypothermia
pacemaker
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10
Q

How will hypothermia affect vital parameters irrespectively of co-existing shock?

A

Reduced RR, Pulse, BP

Resistance against cardiovascular drugs

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11
Q

What are the response to inflammatory activators at anaphylactic shock?

A

Inflammatory activators: Vasodilatation and oedema
Spasmogenics: smooth muscle contraction
Chemotactic agents: Attracts WBC

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12
Q

How is the mechanism of hypovolemia in anaphylactic shock?

A

increased vascular permeability
vasodilatation
decreased venous return secondary to increased thoracic pressure due to bronchospasm

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13
Q

What conditions mimic sepsis?

A
MI
PE
Pankreatit
Fat embolism syndrome
Adrenal insufficiens
Liver decompensation
GI-bleeding
Diuresis
Drug reactions
Transfusion reaction
Procedure related bacteremia
amniotic fluid embolism
advanced malignancy
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14
Q

What principle causes to cardiogenic shock exist?

A

Myocardial (ventricular failure/conduction problems)
Endocardial (valve lesions)
Epikardiell (tamponad, konstriktiv perikardit)

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15
Q

What are classical vital parameters in neurogenic shock?

A

BP 90
Pulse 50
Warm and pink
Could be delayed by initial catecholamine release

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16
Q

Fluids at hypovolemic shock grade I and II?

A

I: 1 litre crystalloid
II: 2 litres of crystalloid

17
Q

Fluids att hypovolemic shock and GI bleeding?

A

Hypotensive resuscitation
Keep BP 20 mmHg below baseline
6 u of blood if 65, NSAID or comorbidity
coagulations tests!

18
Q

What are signs of cardiogenic shock?

A
Central cyanosis 
Bi-basal crackles
Raised JVP
Third heart sound
Murmurs
19
Q

Treatment goals in sepsis if lactate >4 or hypotension

A

20 ml/kg initially (=ca 1500 ml)

Keep MAP >65