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Useful Information > Side-Effects of Common Drugs > Flashcards

Side-Effects of Common Drugs Flashcards

1
Q

CCBs

A
  • Headache
  • Flushing
  • Ankle oedema

NB - Verapamil also causes constipation.

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2
Q

BBs

A
  • Bronchospasm (especially in asthmatics)
  • Fatigue
  • Cold peripheries
  • Sleep disturbances
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3
Q

Nitrates

A
  • Headache
  • Postural hypotension
  • Tachycardia
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4
Q

Nicorandil

A
  • Headache
  • Flushing
  • Anal ulceration
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5
Q

Amoxicillin

A
  • Rash with infectious mononucleosis
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6
Q

Co-amoxiclav

A
  • Cholestasis
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7
Q

Flucloxacillin

A
  • Cholestasis (usually develops after several weeks of use)
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8
Q

Erythromycin

A
  • GI upsret
  • Prolongs QT interval
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9
Q

Ciprofloxacin

A
  • Lowers seizure threshold
  • Tendonitis
  • Increases risk of tendon rupture
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10
Q

Metronidazole

A
  • Reaction following alcohol ingestion
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11
Q

Doxycycline

A
  • Photosensitivity
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12
Q

Trimethoprim

A
  • Rashes, including photosensitivity
  • Pruritis
  • Suppression of haematopoiesis
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13
Q

Metformin

A
  • GI side-effects
  • Lactic acidosis
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14
Q

Sulphonylureas (i.e. glimeprimide, chlorpropamide, glipizide)

A
  • Hypoglycaemic episodes
  • Increased appetite and weight gain
  • SIADH
  • Liver dysfunction (cholestatic)
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15
Q

Glitazones (i.e. pioglitazone, rosiglitazone)

A
  • Weight gain
  • Fluid retention
  • Liver dysfunction
  • Fractures
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16
Q

Gliptins (i.e. sitagliptin, vildagliptin, linagliptin)

A
  • Pancreatitis
17
Q

Glucocorticoids (i.e. prednisolone, dexamethasone, betamethasone)

A
  • Endocrine: impaired glucose regulation, increased appetite/weight gain, hirsutism, hyperlipidaemia
  • Cushing’s syndrome: moon face, buffalo hump, striae
  • Dermatological: thinning of skin, easy bruising
  • Musculoskeletal: osteoporosis, proximal myopathy, avascular necrosis of the femoral head, muscle weakness
  • Immunosuppression: increased susceptibility to severe infection, reactivation of tuberculosis
  • Psychiatric: insomnia, mania, depression, psychosis
  • Gastrointestinal: peptic ulceration, acute pancreatitis
  • Ophthalmic: glaucoma, cataracts
  • Suppression of growth in children
  • Intracranial hypertension
  • Neutrophilia
18
Q

Mineralocorticoids (i.e. fludrocortisone)

A
  • Fluid retention
  • Hypertension
19
Q

Important information about steroids

A
  • DON’T – Don’t stop taking steroids abruptly. There is a risk of adrenal crisis.
  • S – Sick Day Rules. (double dose for 2 days when ill)
  • T – Treatment Card.
  • O – Osteoporosis prevention with bisphosphonates and supplemental calcium and vitamin D.
  • P – Proton pump inhibitor for gastric protection.

Useful Information (11 decks)

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