Signal Transduction

Question 1

Type of signaling wherein signals are send to target cell

Answer 1

Intercellular signaling

Question 2

Type of signaling for signal transduction

Answer 2

Intracellular signaling

Question 3

Types of Intercellular signal

Answer 3

Chemical
Electrical
Cell to cell

Question 4

[Type of Intercellular Signal]

Released in extracellular compartment before it can be received by the target cell

Answer 4

Chemical signal

Question 5

Examples of chemical signal

Answer 5

Hormones, neurotransmitter

Question 6

Types of chemical signal

Answer 6

endocrine, paracrine, autocrine

Question 7

[Type of Chemical Signal] released in the vascular compartment; enters the circulation

Answer 7

endocrine signal

Question 8

[type of chemical signal] binds to receptorss of neighboring cell of a different cell type; enters the interstitial compartment

Answer 8

paracrine signal

Question 9

[type of chemical signal] binds to the cell of origin or neighboring cells of the same cell type

Answer 9

autocrine signal

Question 10

T or F: No cellular receptors, no cellular response

Answer 10

T

Question 11

types of cellular receptors

Answer 11

intracellular receptors, plasma membrane or cell surface receptors

Question 12

[type of intracellular receptor] activates membrane enzyme that will cause the release of secondary messengers

Answer 12

plasma membrane or cell surface receptor

Question 13

types of intracellular receptor

Answer 13

steroid receptor, cytoplasmic receptor

Question 14

types of cell surface receptor

Answer 14

ligand gated ion channels (ionotropic receptor), G-protein coupled receptor, enzyme-linked receptor

Question 15

example of ionotropic receptor

Answer 15

acetylcholine

Question 16

G protein bind to GTP

Answer 16

active

Question 17

G protein bind to GDP

Answer 17

inactive

Question 18

target effectors for G-protein (pathways)

Answer 18

Ion channels, Adenylate cyclase, Phospholipase, Cyclic GMP phosphodiesterase

Question 19

2 types of G protein

Answer 19

Gi and Gs

Question 20

[types of G protein] inhibits adenylyl cyclase

Answer 20

Gi

Question 21

[types of G protein] stimulates adenylyl cyclase

Answer 21

Gs

Question 22

[type of pathway for G protein] triggers response of target cell (Protein Kinase A)

Answer 22

cAMP pathway

Question 23

[types of pathway for G protein] activates Protein Kinase C

Answer 23

Inositol Triphosphate (IP3)

Question 24

types of enzyme-linked receptor

Answer 24

guanylyl cyclase receptor, tyrosine kinase receptor

Question 25

types of tyrosine kinase receptor

Answer 25

true tyrosine kinase, tyrosine kinase associated receptor

Question 26

signal transduction pathways

Answer 26

PI3/AKT1 pathway, MAPK, JAK/STAT, IP3 (PLC)

Question 27

type of signal transduction pathway that activates Protein kinase B

Answer 27

AKT Pathway