Signaling Pathway for Hormones Flashcards

(34 cards)

1
Q

GH

A

Non-Receptor TK

JAK/STAT

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2
Q

GHRH

A

Gs cAMP

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3
Q

What other hormones use cAMP?

A

Calcitonin, GHRH, Glucagon

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4
Q

ACTH

A

Gs cAMP

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5
Q

PTH

A

Gs cAMP

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6
Q

Gastrin

A

Gq IP3

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7
Q

hCG

A

Gs cAMP

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8
Q

Glucagon

A

Gs cAMP

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9
Q

cGMP hormones

A

BNP, ANP, EDRF (NO)

think vasodilators

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10
Q

ADH (V2)

A

Gs cAMP

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11
Q

Non-receptor Tyrosine Kinases PIGGLET

A

Prolactin, immunomodulators (IL-2, IL-6, IFN), GH, G-CSF, EPO, Thrombopoeitin
JAK/STAT Pathway
Think Acidophils and cytokines

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12
Q

Prolactin

A

Non-Receptor TK

JAK/STAT

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13
Q

FSH

A

Gs cAMP

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14
Q

LH

A

Gs cAMP

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15
Q

Receptor Tyrosine Kinase

A

Insulin, IGF-1, FGF, PDGF, EGF

MAP Kinase pathway, think growth factors

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16
Q

IL-2, IL-6, IFN

A

Non-Receptor TK

JAK/STAT

17
Q

What are the acidophils of Anterior Pituitary?

18
Q

Histamine (H1)

19
Q

Calcitonin

20
Q

ADH (V1)

21
Q

GOAT HAG mnemonic

A

IP3

GnRH, Oxytocin, ADH (V1), TRH, Histamine (H1), Ang II, Gastrin

22
Q

TRH

23
Q

GnRH

24
Q

Oxytocin

25
Ang II
Gq IP3
26
Intracellular Receptors PET CAT on TV
Progesterone, Estrogen, Testosterone, Cortisol, Aldosterone, T3/T4, Vit D
27
Insulin
Receptor TK | MAP Kinase
28
MSH
Gs cAMP
29
G-CSF, EPO, Thrombopoietin
Non-Receptor TK | JAK/STAT
30
What are the basophils of Anterior Pituitary?
FSH, LH, ACTH, TSH
31
FLAT ChAMP mnemonic
cAMP FSH, LH, ACTH, TSH, CRH, hCG, ADH (V2), MSH, PTH Think of basophils
32
IGF-1
Receptor TK | MAP Kinase
33
CRH
Gs cAMP
34
TSH
Gs cAMP