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Additional Pharm Exam One (H, E &J) > Simmons Pharm 422 Exam 2 > Flashcards

Simmons Pharm 422 Exam 2 Flashcards

1
Q

Conditions treated by Augmentin (first choice) (4)

A 
Sinusitis 
Impetigo
Cellulitis 
Communication acquired pneumonia
Dog bite

SICC-DAWG!

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2
Q

Conditions treated with Amoxicillin First choice

4

A

Strep throat
Tonsillitis
Otitis media
Pharyngitis

STOP!

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3
Q

First choice antibiotic for meningitis

Ax to brain

A

Cefotaxime or Ceftriaxone

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4
Q

First line antibiotic C-diff

A

Metronidazole or Flagyl

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5
Q

Antibiotic for uncomplicated UTI in adult

A

Bactrim 3days or

Nitrofurantoin 7 days

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6
Q

First line antibiotic for MRSA

The good witch

A

Clindamycn

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7
Q

First line antibiotic treatment for Rickettsia, Lyme

A

Doxycycline

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8
Q

First line antibiotic treatment for pneumonia for mycoplasma

A

Azithromycin

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9
Q

First line antibiotic treatment for Community acquired pneumonia

A

Augmentin

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10
Q

First line antibiotic combo therapy for gonorrhea chlamydia infection

A

Ceftriaxone 250 mg IM

Azithromycin 1g ORAL

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11
Q

First line antibiotic treatment for pertussis

A

Azithromycin

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12
Q

Metronidazole (Flagyl) treats these two conditions

A

Bacterial vaginosis

C-diff

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13
Q

Antibiotics affecting protein synthesis

(Motl (y) crew

A

Macrolides
Oxazolidinones
Tetracyclines
Lincosamides

MOTLEY CREW

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14
Q

Antibiotics affect in Qt Prolongation

FM-am (3)

A

Fluoroquinolones
Macrolides
Anti-malarias
Amiodarone antipsychotics fluconazole

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15
Q

Drugs that affect G6PD

SAM CK

A

Sulfa drugs

aspirin

malaria drugs

high dose vitaminC

high-dose vitamin K

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16
Q

Methemoglobinemia (inducers)

A

Lidocaine spray and nitrates

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17
Q

Optional choices for impetigo or penicillin allergy

A

First second and third generation cephalosporins

Fluoroquinolones

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18
Q

Antibiotic treatment of UTI in pregnancy

A

Amoxicillin

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19
Q

Antibiotic used to treat UTI in children

A

Augmentin or cephalexin

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20
Q

Antibiotic treatment of UTI in geriatric

A

Bactrim
Levofloxacin

NO NITROFURANTOIN!

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21
Q

If allergy to amoxicillin what antibiotic will be used to treat strep throat?

A

Azithromycin

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22
Q

Which 2 antibiotics can cause C-diff infection?

The good witch
Brain biotics

A

Clindamycin and cephalosporins

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23
Q

Which two antibiotics absorption is impaired by dairy consumption

A

Tetracycline and Cipro

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24
Q

Which two antibiotics can cause peripheral neuropathy?

A

Nitrofurantoin

Zyvox

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25
Q

In regard to absorption and pregnancy which functions are increased?

A

Skin penetration
Gastric emptying
Lung absorption

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26
Q

In re: to absorption in pregnancy, which 3 functions are reduced?

A

GI Motility
gastric acid secretion
gastric acidity

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27
Q

Blood volume, total body water, and cardiac output are blank in pregnancy in regard to distribution?

A

Increased

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28
Q

Uterine blood flow, volume of distribution, and fat distribution are all blank pregnancy in regard to distribution?

A

Increased

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29
Q

What one function in regard to distribution is decreased in pregnancy?

A

Plasma protein binding

30
Q

And pregnancy drugs that are excreted primarily by the kidneys show a blank in elimination?

A

Increase

31
Q 
During pregnancy we want to prescribe drugs that are what in terms of :
Protein
fat
Ionization status
molecular weight
A

Highly protein bound
Hydrophilic
Ionized
High molecular weight

32
Q

Drugs to avoid during lactation

A

Chemotherapy
Lithium
Cyclosporin
Methotrexate

33
Q

Are insulin and heparin OK for pregnancy?

A

Yes

34
Q

Meds to avoid during pregnancy

A 
NSAIDs 
Coumadin
Aspirin 
chemotherapy 
Ace inhibitors 
ARBS
35
Q

Which antibiotics should be taken on an empty stomach

A

Levofloxacin
Macrolides
Penicillin

36
Q

Flagyl should be taken with or without food?

A

With food

37
Q

Myelosuppression
Serotonin syndrome
Peripheral neuropathy

Which antibiotic can cause all three?

A

Linezolid (Zyvox)

38
Q

Penicillin, cephalosporins, glycopeptides All inhibitors of what?

A

Beta lacatamase

39
Q

Lincosamides
Oxazoliddones
Macrolides
Tetracyclines

All affect what in bacteria?

A

Protein synthesis

40
Q

Fluoroquinolones
Metronidazole

Most of these affect what in bacteria replication?

A

DNA GYRASE

41
Q

Sulfonomides
Trimethoprim
Nitrofurantoin
All inhibit what in bacteria ?

A

Metabolic pathways

42
Q

If spotting in follicular phase what adjustments need to be made in OCP?

A

More EE

43
Q

Disulfiram reaction caused by these 2 antibiotics

A

Cephalosporins

Flagyl

44
Q

Antibiotic used to tx syphilis and group A strep

A

Penecilin

45
Q

6 conditions PCN treats

UUP SOS

A

URI, pharyngitis, sinusitis, OM, STI, UTI

46
Q

In PCN script what will decrease dose?

A

low GFR

47
Q

Ampicillin and Sulbactam

A

Augmentin

48
Q

Weaken cell wall causing bacteria to absorb water and rupture

A

penicillin

49
Q

CSF action w/inflammation (3/4th)

A

Cephalosporins

50
Q

Which antibiotics are nephrotoxic?

A

Cephalosporins, Glycopetides (Vanco)

51
Q

The antibiotic class that Inhibits folic acid synthesis

A

Sulfonamides (Trimethoprim) Bactrim

52
Q

community acquired MRSA 1st & 2nd line

A

Bactrim first, Clindamycin second due to causing C-diff

53
Q

Levofloxacin, ciprofloxacin, moxifloxacin belong to what class?

A

Flouroquinolones

54
Q

Levofloxacin should be taken…?

A

on an empty stomach

55
Q

Special (renal) considerations when dosing Flouroquinolones

A
  • Decrease dose is CrCl <50
56
Q

Antibiotic that has a metallic taste

A

Matronidazole (Flagyl)

Flouroquinolones

57
Q

Pregnancy Cat C/D (avoid 3rd trimester),
Lactation: avoid
Peds: only >2y/o

A

Bactrim

58
Q

Antibiotic that can cause kernicterus in babies

A

Bactrim

59
Q

Which antibiotics can cause Photosensitivity?

A

Tetracyclines
Bactrim
Flouroquinolones

60
Q

Linezolid Ex: Zyvox is in what class antibiotic?

A

Oxazalidinones

61
Q

what antiobiotic treats these? VRE, MRSA, TB, group A/B strep

A

Oxazalidinones

Linezolid Ex: Zyvox

62
Q

Tetracycline is which bacteriocidal or bacteriostatic?

A

bacteriostatic

63
Q

h. pylori antiobiotics

A

Tetracycline, - Clarithromycin

64
Q

Erythromycin, azithromycin, clarithromycin (Class)?

A

Macrolides

65
Q

Glycopeptides example

A

Vancomycin / Televancin

66
Q

Lincosamides

A

Ex: Clindamycin

67
Q

Options for cellulitis

A

Augmentin

Clindamycin

68
Q

Excellent activity against MSSA, strep, H. flu, M.

catarrhalis, Neisseria meningitides, E. coli, Klebsiella, etc.

A

aminopenicillins

69
Q

• Ineffective against gram-negative anaerobes such as MRSA

A

PCN

70
Q

? are the treatment of choice for mycoplasma pneumonia

A

Macrolides

Additional Pharm Exam One (H, E &J) (2 decks)

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