Skeletal System Flashcards

(37 cards)

1
Q

What are the basic components of the skeletal system

A

Ligament (connects bone to bone)

Bone

Skeletal muscle

Cartilage

Tendon (connects muscle to bone)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the axial skeleton?

A

Bones in skull, vertebral column and thoracic cage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the appendicular skeleton?

A

Bones of the thoracic and pelvic limbs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the types of bones in the skeletal system and examples of each?

A

Irregular bone (vertebrae)

Pneumatic bone (paranasal sinuses)

Flat bone (scapula)

Short bone (carpal bones)

Sesamoid bone- these are small bones embedded in the tendon (patella)

Long bone (femur)

Splanchnic bone (baculum)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are fibrous joints?

A

Bones connected by fibrosis tissue

No joint cavity

Three types:
1. Suture which is immovable
2. Syndesmosis which is slightly movable
3. Gomphosis which is immovable

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are cartilaginous joints?

A

Bones connected by cartilage

No joint cavity

Two types:
1. Synchondrosis which is immovable
2. Symphisis which is slightly movable

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What are synovial joints?

A

Freely movable

Cavities between bones are filled with synovial fluid

6 types:
1. Ball and socket (spheroid joint)- allows the greatest range of movement
2. Plane (gliding joint)- allows only gliding movement
3. Pivot (trochoid joint)- allows movement limited to rotation
4. Condylar (condyloid, ellipsoid, or ellipsoidal joint)- allows angular motions but not rotation
5. Hinge (ginglymus)- movement is limited to flexion and extension
6. Saddle (sellaris joint)- allows all movement except rotation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the simple bone structure?

A

Epiphysis

Metaphysis

Diaphysis (shaft)

Metaphysis

Epiphysis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What are the structures of a long bone?

A

Red marrow

Spongy bone

Epiphyseal line

Compact bone

Medullary cavity

Periosteum

Endosteum

Yellow marrow

Nutrient arteries

Nutrient foramen

Articular cartilage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are the structures of other bones that are not long bones?

A

Periosteum

Red marrow

Compact bone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is compact bone also known as?

A

Cortical bone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is spongy bone and what is it also known as?

A

Also known as Cancellous bone or Trabecular bone

It is a meshwork of supporting bundles of supporting fibres called trabeculae

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

How is blood supplied in bones?

A

Nutrient artery and vein

Periosteal blood vessels- covers the entire length of the bone shaft

Metaphyseal-epiphyseal blood vessels- supply blood to the ends of long bones

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the matrix of a bone?

A

Contains collagen fibres (organic component) and calcium salts (inorganic component)

Hydroxyapatite crystals account for approx 60% of the weight of bones
Collagen fibres account for approx 30% of the weight of bones
Water content is approx 8%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the bone composed of?

A

Matrix

Several types of cells that all differentiated from the same basic cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are osteoprogenitor cells?

A

Mesenchymal cells that divide to produce daughter cells that differentiate into osteoblasts. They maintain the population of osteoblasts

They are found in the periosteum and endosteum

17
Q

What are osteoblasts?

A

They line the surface bone, and make the organic components of the bones matrix. When they are completely surrounded by bine matrix they become osteocytes

18
Q

What are osteocytes?

A

Matured bone cells located in the bone matrix that make up more of the cell population. Mechanosensors- stimulate bone formation in the presence of mechanical stimuli, or degradation in the absence of such stimuli

19
Q

What are bone lining cells?

A

Former osteoblasts and cover bone that is not remodelling. Regulate the movement of calcium and phosphate into and out of bone

20
Q

What are osteoclasts?

A

Bone-resorbing cell. Derived from the same stem cells which produced monocytes and macrophages. Form by the fusion of many cells (50 or more nuclei). Important role in the regulation of calcium and phosphate levels in body fluids

21
Q

Where are blood cells produced?

A

Produced in the red marrow

22
Q

What are the functions of the skeletal system?

A

Support- bones and cartilage peonies the scaffold that supports the body

Movement- contraction of the skeletal muscles move bones, producing body movements

Protection- bone is rigid and protects the organs it surrounds. The skull protects the brain, the vertebrae shields the spinal cord, and the rib cage protects the heart, lungs and other organs of the thorax

Storage- bone acts as a reservoir for minerals important to the body, such as calcium and potassium. Adipose tissue is stored in the yellow marrow and can serve as a source of energy for other tissues

Blood cell production- bone is major site for haematopoiesis. Red blood cells, white blood cells, and platelets are all produced in red marrow

23
Q

What are the main stages of bone formation?

A

Mesenchymal cells

Hyaline cartilage

Primary ossification centre + bone collar

Spongy bone formation + blood vessel penetration

Secondary ossification centre + medullary cavity formation

articular cartilage

Endochondral bone development

24
Q

What does bone growth and development depend on?

A

Balance between bone formation and bone resorption

Osteoclasts are constantly removing bone matrix and osteoblasts are always adding to it. Their actions are balanced

25
What is the process that recycles the organic and mineral components of the bone matrix?
Remodelling
26
What are the stages of bone remodelling?
Activation Resorption- osteoclast progenitors differentiate into osteoclasts Reversal- mononuclear cells differentiate into macrophages Formation- osteoclast progenitors (MSCs) differentiate into osteoblasts Termination
27
What causes bones to weaken?
When osteoclasts remove calcium salts faster than osteoblasts deposit them- osteoporosis
28
What happens when osteoblast activity dominates osteoclasts?
Bones become stronger and denser
29
Why is vitamin C required for bone growth?
Required for collagen synthesis and stimulates osteoblast differentiation
30
What is hypocalcemia?
Milk fever
31
How does the hormone calcitriol affect the skeletal system and what is it's source?
Source: kidneys Promotes calcium and phosphate absorption in the digestive tract
32
How does the growth hormone (GH) affect the skeletal system and what is its source?
Source: pituitary gland Stimulates osteoblast activity and the synthesis of bone matrix
33
How does the hormone thyroxine affect the skeletal system and what is its source?
Source: thyroid gland (follicle cells) With GH, stimulates osteoblast activity and the synthesis of bone matrix
34
How do sex hormones affect the skeletal system and what is their source?
Source: ovaries (for oestrogens), testes (for androgens) Stimulates osteoblast activity and the synthesis of bone matrix
35
How does parathyroid hormone affect the skeletal system and what is its source?
Source: parathyroid glands Stimulates osteoclast (and osteoblast) activity, elevates calcium concentration in body fluids
36
How does the hormone calcitonin affect the skeletal system and what is its source?
Source: thyroid gland (C cells) Inhibits osteoclast activity. Promotes calcium loss by kidneys. Reduces calcium concentrations in body fluids
37
How does the skeletal system assist when there is low calcium ion levels in plasma?
Low calcium ion levels in plasma cause the parathyroid glands to secrete parathyroid hormone (PTH) Osteoclasts stimulated to release stored calcium ions from bone
38
How does the skeletal system assist when calcium ion levels in plasma are high?
Parafollicular cells (C cells) in the thyroid gland secrete calcitonin Osteoclasts inhibited while osteoblasts continues to lock calcium ions in the bone matrix