Sketchy - Cell Wall and Membrane Active Antibiotics - Ampicillin, Amoxicillin, Piperacillin, Ticarcillin Flashcards Preview

MS 2 - Unit 6 > Sketchy - Cell Wall and Membrane Active Antibiotics - Ampicillin, Amoxicillin, Piperacillin, Ticarcillin > Flashcards

Flashcards in Sketchy - Cell Wall and Membrane Active Antibiotics - Ampicillin, Amoxicillin, Piperacillin, Ticarcillin Deck (21):
1

Class:
Ampicillin (IV, PO); amoxicillin (PO)

Aminopenicillins - Beta-lactams

2

Class:
Piperacillin (IV); Ticarcillin

Extended spectrum penicillin - Beta-lactams

3

T/F: Ampicillin, Amoxicillin, Piperacillin, Ticarcillin are bacteriocidal.

True

4

Ampicillin and Amoxicillin may be used against gram positive organisms (Staph and Strep) in addition to:

Gram negative - Ampicillin and Amoxicillin have improved ability to penetrate the gram negative cell wall membrane

Considered "broad spectrum"

5

Which Aminopenicillin has better oral absorption?

Amoxicillin

6

What is an appropriate treatment for streptococcal pharyingitis caused by Strep pyogenes?

Ampicillin, Amoxicillin

7

Amoxicillin is effective against otitis media and sinusitis caused by what organisms?

Strep pneumo;
Haemophilus influenzae;
Moraxella catarrhalis

Can also use Ampicillin and Amoxicillin against pneumonia caused by Strep pneumo; Haemophilus influenzae;

8

Amoxicillin is part of the triple therapy for what infection?

H. Pylori
(with Clarithromycin and a PPI)

9

Early stage Lyme disease, or Lyme disease in young children, can effectively be treated with what penicillin-type drug?

Amoxicillin (an aminopenicillin)

10

IV Ampicillin is recommended for:

Anaerobic infections such as aspiration pneumonia

11

Ampicillin is appropriate for treating Enterococcus, a gram positive bug that causes:

UTIs;
Endocarditis

Ampicillin resistant strains due to beta-lactamase production

12

Use Ampicillin to treat what bug responsible for meningitis in newborns and the elderly?

Listeria

13

Can you use the aminopenicillins (ampicillin, amoxicillin) for GIs and UTIs caused by gram negative rods?

Yes
They are effective against. E. Coli

14

Are aminopenicillins beta-lactamase resistant or sensitive?

Sensitive
Add clavulanate to become beta-lactamase resistant

15

Class:
Tazobactam
Sulbactam

Beta-lactamase inhibitors;
Add to Aminopenicillins

16

Asplenic patients are at higher risk of infection by encapsulated bacteria. What are two of the more common bacteria they are at risk for?

Haemophilus influenzae
Strep pneumoniae

17

What prophylaxis is indicated in patients at risk for endocarditis who undergo dental procedures?

Amoxicillin

18

Adverse effects: Aminopenicillins (Ampicillin, Amoxicillin)

Rash, can progress to SJS;
Skin rashes if given to a patient with mono (EBV)

19

Adverse effects: Amoxicillin-clavulanate

Liver injury

20

Piperacillin-tazobactam extends coverage from gram positives to what important bacterial class?

Anaerobes ie Pseudomonas

21

Ticarcillin-clavulanate extends coverage from gram positives to what important bacterial class?

Anaerobes ie Pseudomonas