Flashcards in Sketchy - Cell Wall and Membrane Active Antibiotics - Ampicillin, Amoxicillin, Piperacillin, Ticarcillin Deck (21):
Ampicillin (IV, PO); amoxicillin (PO)
Aminopenicillins - Beta-lactams
Piperacillin (IV); Ticarcillin
Extended spectrum penicillin - Beta-lactams
T/F: Ampicillin, Amoxicillin, Piperacillin, Ticarcillin are bacteriocidal.
Ampicillin and Amoxicillin may be used against gram positive organisms (Staph and Strep) in addition to:
Gram negative - Ampicillin and Amoxicillin have improved ability to penetrate the gram negative cell wall membrane
Considered "broad spectrum"
Which Aminopenicillin has better oral absorption?
What is an appropriate treatment for streptococcal pharyingitis caused by Strep pyogenes?
Amoxicillin is effective against otitis media and sinusitis caused by what organisms?
Can also use Ampicillin and Amoxicillin against pneumonia caused by Strep pneumo; Haemophilus influenzae;
Amoxicillin is part of the triple therapy for what infection?
(with Clarithromycin and a PPI)
Early stage Lyme disease, or Lyme disease in young children, can effectively be treated with what penicillin-type drug?
Amoxicillin (an aminopenicillin)
IV Ampicillin is recommended for:
Anaerobic infections such as aspiration pneumonia
Ampicillin is appropriate for treating Enterococcus, a gram positive bug that causes:
Ampicillin resistant strains due to beta-lactamase production
Use Ampicillin to treat what bug responsible for meningitis in newborns and the elderly?
Can you use the aminopenicillins (ampicillin, amoxicillin) for GIs and UTIs caused by gram negative rods?
They are effective against. E. Coli
Are aminopenicillins beta-lactamase resistant or sensitive?
Add clavulanate to become beta-lactamase resistant
Add to Aminopenicillins
Asplenic patients are at higher risk of infection by encapsulated bacteria. What are two of the more common bacteria they are at risk for?
What prophylaxis is indicated in patients at risk for endocarditis who undergo dental procedures?
Adverse effects: Aminopenicillins (Ampicillin, Amoxicillin)
Rash, can progress to SJS;
Skin rashes if given to a patient with mono (EBV)
Adverse effects: Amoxicillin-clavulanate
Piperacillin-tazobactam extends coverage from gram positives to what important bacterial class?
Anaerobes ie Pseudomonas