{ "@context": "https://schema.org", "@type": "Organization", "name": "Brainscape", "url": "https://www.brainscape.com/", "logo": "https://www.brainscape.com/pks/images/cms/public-views/shared/Brainscape-logo-c4e172b280b4616f7fda.svg", "sameAs": [ "https://www.facebook.com/Brainscape", "https://x.com/brainscape", "https://www.linkedin.com/company/brainscape", "https://www.instagram.com/brainscape/", "https://www.tiktok.com/@brainscapeu", "https://www.pinterest.com/brainscape/", "https://www.youtube.com/@BrainscapeNY" ], "contactPoint": { "@type": "ContactPoint", "telephone": "(929) 334-4005", "contactType": "customer service", "availableLanguage": ["English"] }, "founder": { "@type": "Person", "name": "Andrew Cohen" }, "description": "Brainscape’s spaced repetition system is proven to DOUBLE learning results! Find, make, and study flashcards online or in our mobile app. Serious learners only.", "address": { "@type": "PostalAddress", "streetAddress": "159 W 25th St, Ste 517", "addressLocality": "New York", "addressRegion": "NY", "postalCode": "10001", "addressCountry": "USA" } }

Skin cancer and Alopecia Treatments Flashcards

(27 cards)

1
Q

What 2 drugs can treat Basal/Squamous cell carcinomas?

A

Vismodegib

Sonidegib

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What 2 drugs can treat Basal/Squamous cell carcinomas?

A

Vismodegib

Sonidegib

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

MOA for Vismodegib and Sonidegib?

A

Inhibits hedgehog pathway

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

These drugs inhibit the hedgehog pathway to treat basal/squamous cell carcinomas

A

Vesmodegib

Sonidegib

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What 2 drugs can treat Melanoma?

A

Dacarbazine

Vemurafenib

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What 2 drugs can treat Melanoma?

A

Dacarbazine

Vemurafenib

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Conventional chemo treatment for Melanoma?

A

Dacarbazine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Dacarbazine treats?

A

Melanoma

- conventional chemo treatment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

MOA for Vemurafenib

A

Inhibits MAP kinase pathway = apoptosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What drug for Melanoma inhibits the MAP kinase pathway to cause apoptosis?

A

Vemurafenib

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

First line of treatment for Alopecia (male and female)?

A

Minoxidil

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

MOA for Minoxidil

A

Vasodilates due to K+ channel opening

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What does Minoxidil cause?

A

Increased growth phase
Reduced rest phase
Enlargement of follicles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

First line of treatment for Alopecia (male and female)?

A

Minoxidil

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

This drug causes vasodilation due to K+ channel opening

A

Minoxidil

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What other drugs are available to treat Alopecia besides Minoxidil?

A

Finasteride
Spironolactone
Flutamide

17
Q

MOA for Finasteride

A

Inhibits Dihydroxytestosterone (DHT)

18
Q

Adverse effects of Finasteride

A

Sexual dysfunction – due to (-) DHT

19
Q

What is an androgen partial agonist to treat female hair loss?

A

Spironolactone

20
Q

What drug to treat Alopecia inhibits DHT?

21
Q

What is Alopecia Areata?

A

Immune mediated inflammatory disorder that causes non-scarring hair loss from many locations

22
Q

What is Alopecia Areata?

A

Immune mediated inflammatory disorder that causes non-scarring hair loss from many locations

23
Q

What is the topical treatment for Alopecia Areata?

A

Diphenylcyclopropenone (DPCP)

24
Q

What is the topical treatment for Alopecia Areata?

A

Diphenylcyclopropenone (DPCP)

25
What is an adverse effect of using Diphenylcyclopropenone (DPCP) to treat Alopecia Areata?
Causes contact dermatitis = CAUSES HAIR GROWTH
26
How does Diphenylcyclopropenone (DPCP) cause hair growth?
Through its adverse effect = contact dermatitis
27
DPCP to treat Alopecia Areata causes contact dermatitis which then causes?
HAIR GROWTH