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Micro > Skin- Viral > Flashcards

Skin- Viral Flashcards

1
Q

What is another name for measles

A

Rubeola

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1
Q

Measles epi

A

Winter/spring Young ages in developing countries Older ages in USA

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2
Q

What are the important proteins for measles

A

Hemagglutinin Fusion Matrix

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3
Q

Immunization of measles

A

Live attenuated vaccine best Given to infants 13-15 months Dont give live to immunocompromised or pregnant Second dose important for sustained immunity

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3
Q

HHV2 in babies

A

Spread via placenta 50% survival Survivors have permanent neuro impairment

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4
Q

Site of measles replications

A

Respiratory muscosal Skin Lymph Other organs

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4
Q

What puts you at risk for molluscum contagiosum

A

Shaving/bikini line wax

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5
Q

Rubella rash is seen when

A

1-2 days after onset of fever

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5
Q

Hand Foot and Mouth characteristics

A

Enterovirus Coxsackievirus A16 Causes fevers/blisters

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6
Q

Lab diagnosis of measles

A

Urine/Pharyngeal samples PCR Culture w/ monkey kidney cells Immuno- look for 4 fold rise in antibody titer

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7
Q

Parapoxvirus characteristics

A

Natural infection of sheep and goats At risk: sheepherders, vets

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9
Q

Measles is transmitted by what method

A

Respiratory spread Contagious 5 days before rash to 4 days after

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10
Q

Congenital rubella characteristics

A

Opacity in eyes

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11
Q

What kind of virus is varicellae

A

DNA

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12
Q

CMV can be seen in these patients

A

Leukemia Lymphoma AIDS

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13
Q

Describe skin of those with measles

A

Kopliks spots Maculopapular rash

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13
Q

What causes Roseola Infantum syndrome

A

Herpes 6B

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13
Q

Condylomata acuminata

A

Genital warts from Herpes

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15
Q

Rubella characteristics

A

Togavirus Enveloped Single stranded RNA One serotype Human reservoir

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16
Q

Roseola infantum syndrome sx

A

Abrupt onset High fever Brief convulsions

17
Q

Treatment for Parvovirus B19

A

Transfusion

18
Q

Tanapox characteristics

A

Africa Sometimes transmission to man Primate handler

19
Q

Stages of chickenpox

A

Macular Papular Vesicular (early stage) Scab

20
Q

Diagnosis of parapoxvirus

A

Look for cylinder and rounded ends wrapped with rope under microscope

22
Q

What is the incubation period of measles

A

7-18 days

22
Q

Late complications of congenital rubella

A

Diabetes Chronic thyroiditis Panencephalitits

24
Q

Characteristics of Measles

A

Paramyxovirus RNA single stranded

24
Q

Rubella lab diagnosis

A

PCR of respiratory secretions Screen for IgG and IgM, not IgM by itself

25
Q

Rubella lab diagnosis of congenital

A

Titer comparison

25
Q

Who is at risk for complications with chicken pox

A

Children with leukemia

25
Q

Characteristics of Poxviridae

A

DNA Double stranded Replicates in cytoplasm Lipid envelope

26
Q

Vaccine for chicken pox

A

Live virus- need to give before exposed to chicken pox

28
Q

Herpes 6B characteristics

A

T cell lymphotropic virus 2 types 6B: Causes Roseola 6A: Adults- found in those with HIV

29
Q

Clinical diagnosis of measles

A

Cough Ronny nose (coryza) Conjunctivitis

30
Q

Herpes Labialis

A

fever blisters Recurrent

31
Q

What carries monkey pox

A

Prarie dogs

32
Q

Gingivostomatitis

A

Infection in children 1-5

34
Q

What are the 3 syndromes of HHV-1

A

Gingivostomatitis Eczema Herpes Labialis Viral encephaslitis

36
Q

How can you tell the difference between primary and secondary dengue

A

LEvels of IgM are smaller in secondary infection

38
Q

Diagnosis of HHV1/2

A

PCR Direct stains (monoclonal fluorescent) Surgical path (Look for multinucleated giant cells… cowdry A intranuclear inclusions)

39
Q

Is rubella congenital

A

Yes can be passed to unborn children- dangerous

41
Q

Problems with Killed vaccines

A

Short lasting immunity Atypical measles syndrome

42
Q

Clinical feature of HPV

A

warts Verruca plana- flat warts

43
Q

Problems with live vaccines

A

Adverse reactions Can be inactivated by heat/time

44
Q

Molluscum contagiosum characteristics

A

DS DNA Causes benign tumor of skin Warts take up color of skin (water wart) Pore in middle of papule

46
Q

Congenital Parvo B19 can cause what

A

Hydrops fetalis

47
Q

Monkey pox characteristics

A

Africa Zoonotics Can spread man to man but slower compared to small pox

48
Q

Complications of measles

A

Encepthalitis Intersitial pneumonia Bacterial superinfections Subacute panencephalitis (worse- die years later)

49
Q

Diagnosis for Zoster

A

ELISA PCR

Micro (14 decks)

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