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Flashcards in Skin- Viral Deck (49):
1

What is another name for measles

Rubeola

1

Measles epi

Winter/spring Young ages in developing countries Older ages in USA

2

What are the important proteins for measles

Hemagglutinin Fusion Matrix

3

Immunization of measles

Live attenuated vaccine best Given to infants 13-15 months Dont give live to immunocompromised or pregnant Second dose important for sustained immunity

3

HHV2 in babies

Spread via placenta 50% survival Survivors have permanent neuro impairment

4

Site of measles replications

Respiratory muscosal Skin Lymph Other organs

4

What puts you at risk for molluscum contagiosum

Shaving/bikini line wax

5

Rubella rash is seen when

1-2 days after onset of fever

5

Hand Foot and Mouth characteristics

Enterovirus Coxsackievirus A16 Causes fevers/blisters

6

Lab diagnosis of measles

Urine/Pharyngeal samples PCR Culture w/ monkey kidney cells Immuno- look for 4 fold rise in antibody titer

7

Parapoxvirus characteristics

Natural infection of sheep and goats At risk: sheepherders, vets

9

Measles is transmitted by what method

Respiratory spread Contagious 5 days before rash to 4 days after

10

Congenital rubella characteristics

Opacity in eyes

11

What kind of virus is varicellae

DNA

12

CMV can be seen in these patients

Leukemia Lymphoma AIDS

13

Describe skin of those with measles

Kopliks spots Maculopapular rash

13

What causes Roseola Infantum syndrome

Herpes 6B

13

Condylomata acuminata

Genital warts from Herpes

15

Rubella characteristics

Togavirus Enveloped Single stranded RNA One serotype Human reservoir

16

Roseola infantum syndrome sx

Abrupt onset High fever Brief convulsions

17

Treatment for Parvovirus B19

Transfusion

18

Tanapox characteristics

Africa Sometimes transmission to man Primate handler

19

Stages of chickenpox

Macular Papular Vesicular (early stage) Scab

20

Diagnosis of parapoxvirus

Look for cylinder and rounded ends wrapped with rope under microscope

22

What is the incubation period of measles

7-18 days

22

Late complications of congenital rubella

Diabetes Chronic thyroiditis Panencephalitits

24

Characteristics of Measles

Paramyxovirus RNA single stranded

24

Rubella lab diagnosis

PCR of respiratory secretions Screen for IgG and IgM, not IgM by itself

25

Rubella lab diagnosis of congenital

Titer comparison

25

Who is at risk for complications with chicken pox

Children with leukemia

25

Characteristics of Poxviridae

DNA Double stranded Replicates in cytoplasm Lipid envelope

26

Vaccine for chicken pox

Live virus- need to give before exposed to chicken pox

28

Herpes 6B characteristics

T cell lymphotropic virus 2 types 6B: Causes Roseola 6A: Adults- found in those with HIV

29

Clinical diagnosis of measles

Cough Ronny nose (coryza) Conjunctivitis

30

Herpes Labialis

fever blisters Recurrent

31

What carries monkey pox

Prarie dogs

32

Gingivostomatitis

Infection in children 1-5

34

What are the 3 syndromes of HHV-1

Gingivostomatitis Eczema Herpes Labialis Viral encephaslitis

36

How can you tell the difference between primary and secondary dengue

LEvels of IgM are smaller in secondary infection

38

Diagnosis of HHV1/2

PCR Direct stains (monoclonal fluorescent) Surgical path (Look for multinucleated giant cells... cowdry A intranuclear inclusions)

39

Is rubella congenital

Yes can be passed to unborn children- dangerous

41

Problems with Killed vaccines

Short lasting immunity Atypical measles syndrome

42

Clinical feature of HPV

warts Verruca plana- flat warts

43

Problems with live vaccines

Adverse reactions Can be inactivated by heat/time

44

Molluscum contagiosum characteristics

DS DNA Causes benign tumor of skin Warts take up color of skin (water wart) Pore in middle of papule

46

Congenital Parvo B19 can cause what

Hydrops fetalis

47

Monkey pox characteristics

Africa Zoonotics Can spread man to man but slower compared to small pox

48

Complications of measles

Encepthalitis Intersitial pneumonia Bacterial superinfections Subacute panencephalitis (worse- die years later)

49

Diagnosis for Zoster

ELISA PCR