Skin- Viral Flashcards

(49 cards)

1
Q

What is another name for measles

A

Rubeola

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1
Q

Measles epi

A

Winter/spring Young ages in developing countries Older ages in USA

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2
Q

What are the important proteins for measles

A

Hemagglutinin Fusion Matrix

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3
Q

Immunization of measles

A

Live attenuated vaccine best Given to infants 13-15 months Dont give live to immunocompromised or pregnant Second dose important for sustained immunity

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3
Q

HHV2 in babies

A

Spread via placenta 50% survival Survivors have permanent neuro impairment

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4
Q

Site of measles replications

A

Respiratory muscosal Skin Lymph Other organs

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4
Q

What puts you at risk for molluscum contagiosum

A

Shaving/bikini line wax

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5
Q

Rubella rash is seen when

A

1-2 days after onset of fever

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5
Q

Hand Foot and Mouth characteristics

A

Enterovirus Coxsackievirus A16 Causes fevers/blisters

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6
Q

Lab diagnosis of measles

A

Urine/Pharyngeal samples PCR Culture w/ monkey kidney cells Immuno- look for 4 fold rise in antibody titer

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7
Q

Parapoxvirus characteristics

A

Natural infection of sheep and goats At risk: sheepherders, vets

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9
Q

Measles is transmitted by what method

A

Respiratory spread Contagious 5 days before rash to 4 days after

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10
Q

Congenital rubella characteristics

A

Opacity in eyes

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11
Q

What kind of virus is varicellae

A

DNA

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12
Q

CMV can be seen in these patients

A

Leukemia Lymphoma AIDS

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13
Q

Describe skin of those with measles

A

Kopliks spots Maculopapular rash

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13
Q

What causes Roseola Infantum syndrome

A

Herpes 6B

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13
Q

Condylomata acuminata

A

Genital warts from Herpes

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15
Q

Rubella characteristics

A

Togavirus Enveloped Single stranded RNA One serotype Human reservoir

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16
Q

Roseola infantum syndrome sx

A

Abrupt onset High fever Brief convulsions

17
Q

Treatment for Parvovirus B19

18
Q

Tanapox characteristics

A

Africa Sometimes transmission to man Primate handler

19
Q

Stages of chickenpox

A

Macular Papular Vesicular (early stage) Scab

20
Q

Diagnosis of parapoxvirus

A

Look for cylinder and rounded ends wrapped with rope under microscope

22
What is the incubation period of measles
7-18 days
22
Late complications of congenital rubella
Diabetes Chronic thyroiditis Panencephalitits
24
Characteristics of Measles
Paramyxovirus RNA single stranded
24
Rubella lab diagnosis
PCR of respiratory secretions Screen for IgG and IgM, not IgM by itself
25
Rubella lab diagnosis of congenital
Titer comparison
25
Who is at risk for complications with chicken pox
Children with leukemia
25
Characteristics of Poxviridae
DNA Double stranded Replicates in cytoplasm Lipid envelope
26
Vaccine for chicken pox
Live virus- need to give before exposed to chicken pox
28
Herpes 6B characteristics
T cell lymphotropic virus 2 types 6B: Causes Roseola 6A: Adults- found in those with HIV
29
Clinical diagnosis of measles
Cough Ronny nose (coryza) Conjunctivitis
30
Herpes Labialis
fever blisters Recurrent
31
What carries monkey pox
Prarie dogs
32
Gingivostomatitis
Infection in children 1-5
34
What are the 3 syndromes of HHV-1
Gingivostomatitis Eczema Herpes Labialis Viral encephaslitis
36
How can you tell the difference between primary and secondary dengue
LEvels of IgM are smaller in secondary infection
38
Diagnosis of HHV1/2
PCR Direct stains (monoclonal fluorescent) Surgical path (Look for multinucleated giant cells... cowdry A intranuclear inclusions)
39
Is rubella congenital
Yes can be passed to unborn children- dangerous
41
Problems with Killed vaccines
Short lasting immunity Atypical measles syndrome
42
Clinical feature of HPV
warts Verruca plana- flat warts
43
Problems with live vaccines
Adverse reactions Can be inactivated by heat/time
44
Molluscum contagiosum characteristics
DS DNA Causes benign tumor of skin Warts take up color of skin (water wart) Pore in middle of papule
46
Congenital Parvo B19 can cause what
Hydrops fetalis
47
Monkey pox characteristics
Africa Zoonotics Can spread man to man but slower compared to small pox
48
Complications of measles
Encepthalitis Intersitial pneumonia Bacterial superinfections Subacute panencephalitis (worse- die years later)
49
Diagnosis for Zoster
ELISA PCR