SL 4 Flashcards

(57 cards)

1
Q

Adenosine triphosphate

A

Stores energy transferred from the breakdown of carbohydrates fats and proteins

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2
Q

Energy products of atp hydrolysis

A

ADP, pi, H

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3
Q

What processes in the body use atp

A

Oxidative phosphorylation, active transport, muscle contraction, endo and exo cytosis, building proteins

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4
Q

3 main metabolic pathways that transfer energy to atp

A

ATP-cp, phosphorylation via glycolytic pathways, oxidative phosphorylation

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5
Q

What process lets off phosphate as a bi product

A

Substrate level phosphorylation

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6
Q

Is ATP- CP anaerobic or aerobic

A

Anaerobic

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7
Q

Enzyme used in ATP-CP

A

Creatine kinase

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8
Q

Location of glycolysis

A

Cytosol

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9
Q

Important enzymes in glycolysis

A

Hexokinase, pfk

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10
Q

Net gain of atp in hydrolysis

A

2

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11
Q

Anaerobic pathway of pyruvate

A

Lactate
SLP

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12
Q

Aerobic pathway of glycolysis

A

Produces a lot atp through the kerbs cycle

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13
Q

Enzyme used in lactate production

A

LDH / lactate dehydrogenase

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14
Q

lactate production is

A

Reversible, by transferring Hydrogen atoms derived from NADH to pyruvate

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15
Q

Reactants of acetyl coa production

A

Pyruvate, coa-sh, nad+

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16
Q

Where does the production of acetyl coa take place

A

Mitochondria

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17
Q

Bi product of acetyl coa production

A

CO2

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18
Q

Where does the Citric acid cycle take place

A

Mitochondrial matrix

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19
Q

Important enzymes in citric acid cycle

A

Citrate synthase and isocitrate dehydrogenase

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20
Q

Rate limiting enzyme in citric acid cycle

A

Isocitrate dehydrogenase

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21
Q

How many atp are produced per Krebs cycle

A

One via GTP

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22
Q

High energy intermediates produced in citric acid cycle

A

3NADH and FADH2

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23
Q

The Krebs cycle is ____ but does not directly use ___

A

Aerobic, oxygen

24
Q

Why is oxphos required for continuous cycles of kreb cycle

A

Regeneration of NAD+

25
Oxidative phosphorylation is a ____ process
Aerobic
26
What is the main source of atp at low to moderate levels of muscle contraction
Oxphos
27
Where are proteins that regulate oxphos found
Inner mitochondrial matrix
28
Clusters of adiopocytes make up
Adipose tissue
29
Hormone responsible for fat catabolism
Lipase
30
Location of beta oxidation
Mitochondrial matrix to break down fatty acids for energy
31
Type one fibers
Slow oxidative
32
Which type of muscle fiber is best for endurance
Type 1
33
Which muscle fiber type has the smallest diameter
Type 1
34
Characteristics of type 2X muscle fibres
- large diameter - low capillaries - low mitochondrial density - low fatigue resistance
35
Type 2A muscle fibers
Fast oxidative
36
Steps of muscle examinations
1. Muscle biopsy 2. Tissue sectioning 3. Tissue staining 4. Analysis
37
Fatigue onset depends on
1. Active myofibers type 2. Intensity/ duration of contractile activity 3. Fitness status of the individual
38
Peripheral fatigue
Due to factors distal of neuro muscular junction Results from accumulation of metabolic products
39
Central fatigue
Due to factors proximal to the NMJ and results from changes within the nervous system, and leads to decreased motor neuron output
40
Peripheral fatigue metabolic effects
Reduced calcium release and reuptake by by SR, reduced sensitivity of the thin filaments to calcium, directly inhibit the binding/ power stroke of cross bridge
41
Central command fatigue
Muscles are not fatigued but the individual stops exercising
42
Function of satellite cells
Muscle growth and adaptation and regeneration
43
Load> tension muscle contraction
Isotonic eccentric
44
Neural effects that influence force generation
Frequency fiber is stimulated, and the number of muscle fibers stimulated
45
Physiological processes that require atp
OXPHOS, muscle contraction, endo and exocytosis
46
Metabolic bi products of anaerobic glycolysis
ADP hydrogen and lactate
47
Organs found in the CNS
brain and spinal cord
48
Astrocytes
Anchoring neurons to capillaries and supporting the formation of the blood brain barrier
49
Enzyme responsible for ATP-CP
Creatine kinase
50
Oxidative phosphorylation enzyme
ATP synthase
51
Anaerobic glycolysis / lactate production enzyme
Lactate dehydrogenase
52
Anaerobic glycolysis / lactate production
Lactate dehydrogenase
53
Krebs cycle enzyme
Citrate synthase
54
Pyruvate to acetyl coa reaction enzyme
Pyruvate dehydrogenase
55
First source of energy for immediate fast exercise
ATP -CP
56
Glycolysis enzymes
Hexokinase and pfk
57
Type 2B muscle fibers
Fast glycolytic