Sleep- BZDRAs General Information

Question 1

Most commonly used insomnia treatment

Answer 1

BZDRAs

Question 2

Caution in BZDRAs

Answer 2

Anaphylaxis, facial angioedema, complex sleep behaviors

Question 3

When should you take a BZDRA?

Answer 3

Bedtime

Question 4

BZDRAs are FDA-approved for what?

Answer 4

Insomnia

Question 5

BZD hypnotic features

Answer 5

Reduce sleep latency

Increase stage 2 sleep, decrease delta sleep

Anxiolytic effect

Question 6

What patients should avoid BZD hypnotics?

Answer 6

Sleep apnea, substance abuse

Question 7

What should you avoid when taking BZD hypnotics?

Answer 7

Alcohol and CNS depressants

Question 8

The side effects of BZD hypnotics are what: dose dependent or independent?

Answer 8

Dose dependent

Question 9

Non-BZD GABAa agonists are also known as what?

Answer 9

Z-drugs

Question 10

Features of Z-drugs

Answer 10

More selective

Increase total sleep time

Less disruptive of sleep stages

Generally have less withdrawal, tolerance, and rebound insomnia

Associated with parasomnic episodes with amnesia (sleepwalking, sleep-driving, etc.)

Question 11

BZDRAs should be used with caution in what population?

Answer 11

Elderly

Question 12

BZDRA ADEs

Answer 12

drowsiness, dizziness, confusion, fall risk

Question 13

What can occur upon abrupt D/C of a BZDRA?

Answer 13

Tremors, muscle cramps, dizziness