Sleep stuff Flashcards

(64 cards)

1
Q

penile erections

A

REM sleep

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2
Q

Easily awakened with hypnic myoclonia

A

Stage 1 NREM

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3
Q

periods of muscle tone and relaxation

A

stage 2 NREM sleep

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4
Q

enerusis, somnambulance, night terrors

A

stage 3-4 NREM

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5
Q

deeper levels of mental functioning occur

A

stage 3-4 NREM

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6
Q

strengthens immune system

A

stage 3-4 NREM

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7
Q

time of mending for repairing and regenerating muscle

A

stage 3-4 NREM sleep

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8
Q

delta wave sleep

A

Stage 3-4 NREM

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9
Q

disoriented w amneisa if woken in this stage

A

Stage 3-4 NREM

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10
Q

constant waking during this stage may cause immunodeficiency conditions

A

stage 3-4 NREM

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11
Q

what stage is increased physiologic activity

A

RR, BP, HR
spontaneous penile erections
REM Sleep

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12
Q

what stage is near total paralysis of muscles

A

REM sleep

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13
Q

low serotonin

A

less sleep

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14
Q

more NE

A

less sleep

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15
Q

more melatonin

A

more sleep

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16
Q

more dopamine

A

less sleep

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17
Q

at what age is Stage 4 NREM nearly absent by

A

70

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18
Q

What is the diagnostic criteria for insomnia?

A

1+ of the following for 1 month:
* Difficulty initiating/maintaining sleep
* Nonrestorative or poor quality sleep
* Early morning awakening

Symptoms occur DESPITE adequate opportunity/circumstances for sleep
Impaired sleep producing daytime function deficits

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19
Q

Decreased REM, decreased sleep latency, increased stage 1, increased wakefullness

A

alcohol abuse effects on sleep

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20
Q

Consider TCA’s or anxiolytics (benzos) for the SE of sedation and somnolence…

A

secondary insomnia

primarily you want to treat underlying cuase

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21
Q

first line Tx for insomnia

A

CBT

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22
Q

what are the OTC 1st gen antihistamines

A

Benadryl
doxylamine

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23
Q

what are the benzo receptor agonists

A

sonata
ambien
lunesta

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24
Q

what are the melatonin agonists

A

melatonin OTC, ramelteon/rozerem

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25
what are the benzos used for insomnia
restoril (remazepam) fluazepam (dalmane)
26
what are the dual orexin receptor antagonists
all end in orexin
27
what antidepressents do we use in insomniacs
doxepin (TCA) trazodone (zzzzzzz) mirtazapine/remeron
28
what insomnia drug is preferred in pregnancy
doxylamine
29
what drug is avoided in obese patients
mirtazapine/remeron
30
occurs for 3+ months at least 2-6 times/day
narcolepsy
31
Multiple sleep latency test
narcoolepsy diagnosis
32
Treated with modafinil, methylphenidate or dextroamphetamine
these are stimulant drugs used in narcolepsy also treated w SSRIs/SNRIs and forced naps
33
treated w SSRIs/SNRIs and forced naps
narcolepsy also treated w modafinil, methylphenidate or dextroamphetamine (stimlulants)
34
Risk factors of sleep deprivation, GERD, sleep apnea and acute stress
somnambulism
35
what phase of sleep does bruxism occur
NREM sleep
36
pt has headaches and TMJ, what sleep disorder do they likely have
bruxism
37
is advanced sleep phase type more common in younger patients or elderly
elderly
38
what patients have non-24 hour sleep wake rhythm type circadian rhythm disorders
blind paients
39
what type of patients are likely to have irregulat sleep-wake circadian rhythm disorder
developmental issues with children
40
how to treat advanced sleep circadian rhythm disroder
bright liht in evening
41
what are the pharm treatments for circadian rhythm disorders
melatonin (resynchronize) stimulants (caffeine and modafinil)
42
sleep apnea criteria
breath cessation for 10 seconds
43
hypopnea criteria
decreased airflow resultsing >4% decrease in O2
44
central sleep apnea
Absent ventilatory effort throughout episode
45
obstructive sleep apnea
Persistent ventilatory effort but obstructed
46
mixed sleep apnea
Absent ventilatory effort precedes the obstruction
47
RV dysfunction
obstructive sleep apnea
48
overnight polycomnography what for and what include
obstructive sleep apnea includes EEG, electrooculography, EMG, EKG, pulse ox, and end tidal co2 monitoring
49
sinus arrest or AV block may occur
bradydysrhythmias in sleep apnea
50
paroxysmal SVT or v tach
tachydysrhythmias in sleep apnea
51
Facilitate GABA-mediated inhibition of cell firing
MOA of a benzo receptor agonist
52
stage 1 NREM sleep reduction, decrease in REM, does not reduce stage 3. what med
benzo receptor agonist
53
benzo receptor agonist w short half life that is not indicated in long term use
zaleplon/sonata
54
BBW for no use in complexsleep related disorders
benzo receptor agonistrs
55
avoid with grapefruit juice, meals, sedatives
ambien
56
good sleep onset and sleep maintenance insomnia medication
ambien and lunesta
57
good sleep onset med, bad sleep maintenance med
sonata ramelteon/rozerem
58
benzo receptor agonist w longest half life
lunesta
59
desensitized receptors can occur with chronic use of this med
melatonin
60
avoid w coumadin and hypotension
OTC melatonin
61
avoid use w fluvoxamine/luvox
ramelteon/rozerem
62
interacts w CYP3A4
orexin receptor antagonists
63
requires dose adjustment for elderly
daridorexant
64
only schedule 3 drug in sleep lecture and why
sodium oxybates, date rape drug. strong CNS depressant