Small Ruminant Viruses

Question 1

Viruses that induce tumours are called

Answer 1

Oncogenic viruses

Question 2

Process of changing a normal cell to a tumour cell is called?

Answer 2

Transformation

Question 3

Tumour cells result due to genetic changes in what?

Answer 3

• Cell proliferation
• Cell differentiation
• Apoptosis/ programmed cell death

Question 4

The two groups of tumor genes are

Answer 4

Proto-oncogenes and tumor supressor genes

Changes in one or both leads to uncontrolled cell growth

Question 5

What do proto-oncogenes do?

Answer 5

promote cell growth

Question 6

What do tumour suppressor genes do?

Answer 6

Controls proto-onco genes

Question 7

Cells stay in what cell phase their entire life? (except stem cells)

Answer 7

G0/G1

Question 8

Oncogenic DNA viruses do what?

Answer 8

encode inhibitors to tumour supressor genes

Question 9

Example of DNA oncogenic viruses?

Answer 9

Pox, herpes, papilloma, polyoma, hepadna

Question 10

What do RNA oncogenic viruses do?

Answer 10

Encode homologs of oncoproteins

Question 11

What does OPA stand for?

Answer 11

Ovine pulmonary adenocarcinoma

Question 12

What are other names for OPA?

Answer 12

Jaagsiekte, Ovine pulmonary carcinoma, others