SNARE2 Flashcards
1
Q
What does temperature shock to droso cause
A
Paralysis
2
Q
What does KO in these cause: VAMP2 Syntaxin 1A 1B SNAP25
A
Death
no gross abn
die
die
3
Q
What kind of disease do these mut cause VAMP2 SNAP25 SNAP29 Syntaxin II
A
coord and mov pb
intellec, speech
skin pb
FHL
4
Q
What does mut in S75P cause
Give details
A
Slows rate of lyposome fusion
= Ser to Pro mut => dominant negative
