Solid Dosage Form

Question 0

Binder is most effective when added in ______

Answer 0

Solution

Question 1

One of the most effective binder is ________

Answer 1

Microcrystalline cellulose

Question 2

What type of excipients is important for adhesiveness, and adds to the cohesive strength already provided by the diluent?

Answer 2

Binders

Question 3

Disintegrating agents are added to the tablet formulations to facilitate disintegration when the tablet contacts ____ in the ______

Answer 3

Water

GI tract

Question 4

Minimum tablet weight is generally ____

Answer 4

50 mg

Question 5

Most lubricants are _______ and reduce rates of tablet _________

Answer 5

Hydrophobic

Disintegration

Question 6

Glidants are added to tablet formulation in order to improve ____ of the granulation

Answer 6

Flow properties

Question 7

What type of excipients act by reducing interparticulate friction?

Answer 7

Glidants

Question 8

PVP and gelatin are example of what type of excipients

Answer 8

Binders

Question 9

Surfactants and waxesevare example of what type of excipients

Answer 9

Lubricants

Question 10

Cornstarch and silica derivatives are what type of excipients?

Answer 10

Glidants

Question 11

Purpose of granulation

Answer 11

To get better flow property

To get consistent size, ensure content uniformity

Question 12

Capsules are composed of _____ which is obtain by the partial hydrolysis of _______ from the skin, white connective tissue, and bones of animals.

Answer 12

Gelatin

Collagen

Question 13

Most soft gelatin capsules are prepared by the _______

Answer 13

Rotary die process

Question 14

Define rheology

Answer 14

The study of flow of liquids and the deformation of solids

Question 15

_______ are compressed tablet with no disintegrant, it’s primarily used for local or systemic effect

Answer 15

Lozenges

Question 16

____ tablet dissolves in glass of water prior to administration, _____ breaks tablet and liberates active ingredient

Answer 16

Effervescent

Co2

Question 17

Quantity of fill in the ______ determines the weight of the tablet

Answer 17

Die

Question 18

The requirement for content uniformity is met if the amount if active ingredient in each dosage unit lies within the range of _______

Answer 18

85% to 115%

Question 19

During production, sample tablets are periodically removed for ______ and _________

Answer 19

Visual inspection

Automated physical measurement

Question 20

Friability is a measure of how easy it is for a solid to ______

Answer 20

Crumble

Question 21

Capsules are assumed to have better ______ than tablets

Answer 21

Bioavailability

Question 22

Hard gelatin capsules are good for ________ compounding

Answer 22

Extemporaneous

Question 23

Hard gelatin capsules cannot be used with ___

Answer 23

Liquids

Question 24

Hard gelatin capsules is more ubiquitous than ________, soft gelatins capsule is more difficult to _____ that hard gelatin

Answer 24

Soft gelatin capsule | Make

Question 25

binders are added to tablet formulation to increase ________ to powder thereby providing the necessary binding to form ___

Answer 25

Cohesiveness | Granules

Question 26

Excipients are inactive ingredient found in dosage for, it is usually included in solid dosage form for ________ but can have a profound effect on _______ in the body

Answer 26

Manufacture | Pharmokinetics

Question 27

Lubricant reduce friction during ______ and _________ cycle

Answer 27

Compression | Ejection

Question 28

Lubricants prevent _______ of tablet materials to _____ and _____

Answer 28

Adherence | Dies punches

Question 29

Glidants are added to tablet formulation in order to improve _______of granulation

Answer 29

Flow properties

Question 30

Typical wet granulation excipients include:

Answer 30

Diluent Disintegrant Binder Lubricant

Question 31

Dry granulation is used when materials cannot be prepared by wet granulation due to its sensitivity to _____ and ______

Answer 31

Moisture | Heat

Question 32

In what granulation method, powdered mixture is compacted in large pieces and subsequently broken down or sized into granules?

Answer 32

Dry granulation

Question 33

For dry granulation to work, either active ingredient or diluent must have _____ properties

Answer 33

Cohesive

Question 34

In dry granulation, _____ and ____ are not added in the granulation process

Answer 34

Water | Binder

Question 35

DI-TAB is a binder for ______ process

Answer 35

Direct compression

Question 36

effervescent granule may contain mixture of _______

Answer 36

Citric acid | Tartaric acid