Solid Dosage Form Flashcards
Binder is most effective when added in ______
Solution
One of the most effective binder is ________
Microcrystalline cellulose
What type of excipients is important for adhesiveness, and adds to the cohesive strength already provided by the diluent?
Binders
Disintegrating agents are added to the tablet formulations to facilitate disintegration when the tablet contacts ____ in the ______
Water
GI tract
Minimum tablet weight is generally ____
50 mg
Most lubricants are _______ and reduce rates of tablet _________
Hydrophobic
Disintegration
Glidants are added to tablet formulation in order to improve ____ of the granulation
Flow properties
What type of excipients act by reducing interparticulate friction?
Glidants
PVP and gelatin are example of what type of excipients
Binders
Surfactants and waxesevare example of what type of excipients
Lubricants
Cornstarch and silica derivatives are what type of excipients?
Glidants
Purpose of granulation
To get better flow property
To get consistent size, ensure content uniformity
Capsules are composed of _____ which is obtain by the partial hydrolysis of _______ from the skin, white connective tissue, and bones of animals.
Gelatin
Collagen
Most soft gelatin capsules are prepared by the _______
Rotary die process
Define rheology
The study of flow of liquids and the deformation of solids