Sound pathways and Big PIcture stuff/Toris Flashcards

(124 cards)

1
Q

What is the auditory signaling pathway (start from cochlear nerve, so after sound gets through ear etc)?

A

** note the trapezoid body was drawn in in yellow
-this is another major bilateral crossover point

Turns out the cochlear nuclei fibers decussate in the trapezoid body

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are the 3 places in the auditory signaling pathway that send information bilaterally/crossover?

A

Trapezoid body
lateral lemniscus commissure
Inferior colliculus commissure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the main role for the superior olivary nuclei? (actually 2 roles in different sides of nuclei)

A

medial division of SON = compare time lag
-this is where it sends olivocochlear bundle to outer hair cells??

Lateral division of SON = compares intensity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Where do endolymph and perilymph live? what is the difference between the two?

bonus for special hidey hole for perilymph

A

Endolymph is in scala media
-has higher K+, lower Na+

Perilymph is in scala vestibuli & tympani
-has higher Na+, lower K+

Bonus, perilymph also lives in the Tunnel of COrti! (inside scala media.organ of corti)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Where is the primary auditory cortex?

What do the 2 areas of PAC deal with respectively?

A

Heschl’s gyrus (Brodmans area 41) - transverse temporal gyrus

(lateral part of the PAC deals with low frequency, medial part deals with high frequency)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Name the parts of this picture?

A
  1. scala vestibuli
  2. scala media
  3. scala tympani

light green = reissners membrane
light yellow = basilar membrane
pale purple blob= organ of corti
light blue = osseous spiral lamina (which also separates SV & ST?)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Describe the conduction of sound through the ear

A

pinna–>EAM–>TM–>ossicles–>hit oval window–> create vibrations/wave in fluid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

the frequency of vibrations through the fluid determines what aspect of sound

A

frequency = pitch

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

the amplitude of vibrations through the fluid determines what aspect of sound

A

intensity (decibels)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Describe the nerve fibers of the organ of corti

A

they attach to basilar membrane & receive sound conduction
-short fibers are proximal & get HIGH frequncy
-long fibers are distal & get LOW frequency

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Where is the tectorial membrane? What does it do?

A

it sits on top of the hair cells
when endolymph moves, it moves the tectorial membrane and causes move/shearing of hair cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what are outer hair cells used for? are there a lot or a little of them?

A

outer hair cells are for fine tuning

there are MANY rows of them

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What are inner hair cells used for? are there a lot or a little of them?

A

Inner = auditory conduction

there is only ONE row of inner hair cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What runs through the Tunnel of corti?

A

perilymph (surprise!) and CN VIII fibers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

How does tectorial membrane shearing cause sound transduction?

A

when it shears –>K+/Na+ influx –> release of glutamate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

how do the outer hair cells help with sound transduction?

A

amplify movements of basilar membrane
separate background noise from important signals (remember they are the fine tuners)

*receive input from medial olivocochlear system

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What is the vestibule for and what structures does it contain?

A

It is for balance

it has the utricle & saccule in it, which detect acceleration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

what do semicircular canals detect?

A

rotation of the head

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What vessels provide blood supply to the TM?

A

anterior tympanic artery & stylomastoid branch of posterior auricular artery

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What nerves/branches provide sensory innervation of the tM?

A

external TM = auriculotemporal N (CN V3) & auricular branch of CN X (GSA)

internal = tympanic branch of CN IX (GVA)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

What reflex does irritation of the TM cause?

A

CN X cough reflex

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Where does the pharyngotympanic tube open up? be very specific

A

opens posterior to inferior meatus in the nasopharynx by the levator/tensor veli palatini mm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

What provides blood supply to pharyngotympanic tube?

A

ascending pharyngeal artery and maxillary artery

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

what provides blood supply to the auricle of the ear?

A

superficial temporal artery & posterior auricular artery

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
What provides blood supply to EAM of the ear? (3 of them)
superficial artery of the superficial temporal artery & posterior auricular artery & deep auricular artery
26
What provides lymph drainage for the EAM?
deep cervical nodes
27
what provides lymph drainage from the auricle?
parotid, mastoid and superficial cervical nodes
28
Can you describe the innervation to the external ear? The answer is a good picture that maybe you can just remember
29
What is the middle ear/tympanic cavity continuous with?
it is continuous with mastoid air cells and nasopharynx
30
There are 4 important nerves in the tympanic cavity, can you name them?
Tympanic nervous plexus - sensory to mucosa -Tympanic branch of CN IX and carotid sympathetic plexus Chorda tympani (CN VII) - SVA taste, GVE-P submandibular/lingual glands -Passes between malleus and incus to exit petrotympanic fissure CN VII - innervation to stapedius m Lesser petrosal n. - GVE-P from CN IX innervate parotid gland
31
In the ear, what structures does the surface ectoderm form?
cochlear duct, otic ganglia, semicircular canals
32
In the ear, what structures does the mesenchyme form?
scala vestibuli scala tympani
33
In the ear, what structures do the epithelial cells form?
sensory hair cells
34
In the ear, what structures do the neural crest cells form?
ear ossicles!!!
35
In the ear, what structure is made up from the surface ectoderm + mesenchyme + endoderm?
tympanic membrane
36
Breifly tell me the embryology formation [that occurs week] of some of ear's important structures
wk 4: otic placode develops -->becomes otic vesicle -->becomes *statoacoustic ganglia of CN VII & NC cells* -Ventral vesicle => saccule & cochlear duct -Dorsal vesicle => utricle, semicircular canals, endolymphatic duct wk 6: cochlear duct formation wk 7: spiral organ of corti develops wk 8: 2.5 spirals of cochlea are present * this might be pretty important*
37
For pharyngeal arch #1, what are: a) bones/cartilage it forms b) nerves it forms c) pouch d) cleft
a) Maxilla, mandible, zygomatic, vomer Malleus, incus - inner ear b) CN V, V2 - maxillary, V3 - mandibular c) Auditory tube, Middle ear **TM forms here where pouch/cleft meet d) EAM
38
For pharyngeal arch #2, what are: a) bones/cartilage it forms b) nerves it forms c) pouch d) cleft
a) Styloid process, stylohyoid ligament, lesser horn/superior body of hyoid, Stapes - inner ear b) CN VII c) tonsillar sinus & palatine tonsils d) NOTHING [this closes]
39
For pharyngeal arch #3, what are: a) bones/cartilage it forms b) nerves it forms c) pouch d) cleft
a) greater horn/inferior body of hyoid b) CN IX c) DORSAL - inferior parathyroid glands VENTRAL - thymus d) none
40
For pharyngeal arch #4 & 6, what are: a) bones/cartilage it forms b) nerves it forms c) pouch d) cleft
a) thyroid, cricoid, arytenoid cartilage CN 4 b) superior laryngeal N CN 6 b) recurrent laryngeal N c) CN4 ventral ultimo pharyngeal body CN4 dorsal superior parathyroid gland d) none note: Ultimopharyngeal body => C cells => calcitonin
41
For pharyngeal arch #5, what are: a) bones/cartilage it forms b) nerves it forms c) pouch d) cleft
trick question! It doesn't form anything!!! nothing for a, b, c, d
42
what are the 3 major roles of the vestibular system?
1. generate eye movements to compensate for head movements 2. adjust posture relative to head position 3. mediate awareness of movement
43
In the vestibular system, which afferents and efferents are responsible for generating eye movements that compensate for head movements?
○ Afferent: CN VIII ○ Efferent: reticular formation, CN nuclei (abducens, oculomotor, trochlear)
44
In the vestibular system, which afferents and efferents are responsible for adjusting posture relative to position of the head?
○ Afferent: CN VIII ○ Efferent: cerebellum and SC
45
In the vestibular system, which afferents and efferents are responsible for mediating awareness of movement?
○ Afferent: CN VIII ○ Efferent: thalamus to cortex
46
In detail, tell me how the kinetic layrinths detect head rotational acceleration?
○ Contralateral lateral ducts work in concert (ex: contralateral anterior work with posterior) ○ Cristae ampullaris lie in each duct and respond to the shifting of endolymph --> Shifts of the culpa move the stereocilia of the hair cells and stimulate transduction -->Stereocilia deflection => open ion channels => K+ influx => Ca2+ influx => glutamate released
47
Tell me how the static layrinths detect linear acceleration? moreso, tell me the static labyrinths and which type of motion they detect
-Saccule = vertical motion -Utricle = horizontal motion -Together = otolith organs Macula: area containing hair cells Otoconia: calcium carbonate substance which moves the hair cells in order to transduce
48
What are the 3 tracts that make up the vestibular system/pathway?
1. medial vestibulospinal tract 2. lateral vestibulospinal tract 3. vestibulocerebellar tract
49
For the medial vestibulospinal tract, tell me: 1. what function(s) does it do? 2. what reflex is associated with it? 3. where do the signals go/travel?
1. Stabilizes head position when walking AND coordinates eyes and head movement 2. Vestibulocollic reflex 3. Descends MLF - bilateral
50
For the lateral vestibulospinal tract, tell me: 1. what function(s) does it do? 2. what reflex is associated with it? 3. where do the signals go/travel?
1. Compensates for tilts and movement of body with posture changes 2. Vestibulospinal reflex 3. Ipsilateral ...
51
For the vestibulocerebellar tract, tell me: 1. what function(s) does it do? 2. where do the signals go/travel?
1. Takes vestibular information to cerebellum for processing AND helps with balance, posture, coordination of vestibular reflexes 2. One path synapses at vestibular nuclei other at vestibular ganglia
52
What is the only system to connect directly to th cortex (skips the thalamus)?
olfaction
53
Heres a tough one: Describe olfactory pathway that odorants trigger all the way until it creates an AP
Odorants bind to cillia (dendrites) of olfactory neurons --> Receptor (gpcr) changes conformation to interact with G protein --> Inhibitory subunits fall off -alpha subunit activated --> Alpha subunit activates Adenylate Cyclase --> makes cAMP --> cAMP gated channels open -->Ca2+ influx & depolarization -->Ca2+ gated Cl- channels open => cl- efflux => depolarization to THIS GENERATES AP at axon of 1 neuron** **standard voltage gated Na+ channel depolarization to lead to propogation of AP
54
Another tough one: Describe the olfactory pathway from when an AP is created to the cortex?
1. olfactory nerve synapses with olfactory tract in olfactory bulb -Some input dampened by granule cells ○ -Feedback sent to ipsi/contralateral bulbs via anterior limb of anterior commissure 2. Linking of olfactory tracts is important for locating smell 3. axons go up through lateral olfactory stria to ipsilateral primary olfactory cortex and amygdala -primary olfactory cortex = piriform + periamydaloid cortex 4. projections sent to anterior entorhinal cortex (aec) -AEC associated with hippocampus and memory formation 5. AEC projections and piriform cortex go to orbitofrontal olfactory area - YAY!
55
What are the layers of the Olfactory bulb/tract?
1. Olfactory nerve layer 2. Glomerular layer ** 3. External plexiform layer (tufted cells) 4. Mitral cell layer 5. Internal plexiform layer 6. Granular cell layer **this is synapse area where olfactory neurons interact with mitral an tufted cells
56
What are mitral cells, tufted cells, and granule cells? what does each do?
mitral - primary output cells that carry info to primary olfactory cortex and anterior olfactory nucleus Tufted cells: secondary output cell - caries info to primary olfactory cortex and anterior olfactory nucleus Granule cells: inhibitory - no axons - controlled by centrifugal fiber input
57
Alright, lets do this. The gustatory pathway...go!
58
Label the pictures/numbers (recommend writing down on piece of paper then checking, or on your phone)
1. greater petrosal N. (branch of CN 2. geniculate ganglia 3. CN VII 4. Lingual N [of CN VII] 5. chorda tympani 6. Lingual branch of CN IX 7.Inferior glossapharyngeal ganglia 8. CN IX 9. superior laryngeal n. 10. inf. ganglia of the vagus 11. CN X 12. rostral nucleus of the solitary tract [in the medulla] (aka gustatory nucleus of solitary) 13. central tegmental tract 14. Ventral POsteromedial nucleuas (VPM) 15. primary gustatory cortex [in the insula]
59
whats the histo of taste buds
psuedostratified columnar embedded in stratified squam
60
Describe Type I cells of taste buds
Type I - sustentacular cells: nourishment/environment maintenance
61
Describe/explain type II cells of taste buds (what they taste, how they taste them for certain a certain taste, type of synapse, and GPCR structure)
Type II - Tastant receptors: sweet, umami, bitter -Things to crave -Generate APs and release ATP -Signal salty via ENaC -Do NOT form true synapses -Umami/sweet - venus flytrap domain heterodimer, GPCR -Bitter - monomer, GPCR
62
Describe Type III cells of taste buds
Type III - signals sour -Things to avoid ○ -H+ influx forms AP and neurotransmitter release -Forms true synapses
63
Describe Type IV cells of teste buds
Type IV - basal cells
64
HOw is mastication controlled? WHat does this thing coordinate movements between?
Central Pattern Generator CPG controls mastication -it coordinates the movements between: -motor nucleus V -motor nucleus VII -hypoglossal nucleus
65
What is deglutition?
Swallowing
66
What are the phases of deglutition? (4)
1. oral prepatory 2. oral transport 3. pharyngeal 4. esophageal
67
What are the afferent nerves involved in swallowing? (also what nuclei are involved)
Afferent = CN V, VII, IX, X Nuclei: -mesencepalic nucleus of V -main sensory nucleus of V (semilunar ganglion) -nucleus of solitary tract (inferior ganglion IX/X)
68
What are the efferent nerves involved in the swallowing process? Also tell me the nuclei involved in this efferent part
Efferent: CN V, VII, IX, X, XII Nuclei: -MOtor Nuc V -Motor Nuc VII -Nucleus Ambiguus -hypoglossal nuc
69
What are the parts of the brain involved in wakefulness?
Thalamus Midbrain reticular formation Lateral & posterior Hypothalamus
70
What are the roles of ventral & dorsal paths of the midbrain reticular formation in wakefulness?
Dorsal pathway: content of consciousness Ventral path: level of consciousness
71
What are the roles of the lateral and posterior hypothalamus in wakefulness?
-they have orexin containing nucleus -tuberomamillary nuclei --> uses histamine as neurotransmitter
72
What are the 2 portions of the brain/CNS that are related to sleep? How does each help with sleep?
Ant. Hypothalamus -lateral preoptic nuclei = promote sleep by inhibiting orexin containing nuclei & tuberomamillary nuclei Pontine reticular formation - intiates REM sleep
73
Tell me the type of waves observed in the awake stage?
alpha - eyes closed beta - eyes opened & highest frequency
74
What are the frequency/amplitude of each type of wave associated with sleep? (alpha, beta, theta, sleep spindles, k complexes, delta, and REM)
alpha - middle frequency beta - highest frequncy theta - low frequency, low amplitude delta - low frequency, high amplitude sleep spindles - bursts of high frequency k complexes - high amp
75
What waves are seen in Stage I of sleep?
alpha - middle frequency theta - low frequency, low amplitude
76
What waves are seen in Stage II of sleep?
theta - low frequency, low amplitude sleep spindles - bursts of high frequency k complexes - high amp
77
What are the waves seen in Stage III of sleep?
delta - low frequency, high amplitude sleep spindles - bursts of high frequency
78
What waves are seen in Stage IV of sleep?
Delta waves - low freq
79
What waves are seen in REM?
Increased frequency of waves, resembles awakened state waveform
80
Name the afferent nerve and efferent nerve involved in the jaw jerk reflex?
Jaw Jerk aff: CN V eff: CN V
81
Name the afferent nerve and efferent nerve involved in the pupillary light reflex?
Pupillary light reflex aff: CN II eff: CN III
82
Name the afferent nerve and efferent nerve involved in the corneal blink reflex?
corneal blink reflex aff: CN V1 eff: CN VII
83
Name the afferent nerve and efferent nerve involved in the gag reflex?
GAg reflex aff: CN IX eff: CN X
84
Name the afferent nerve and efferent nerve involved in the cough reflex?
cough reflex aff: CN X eff: CN X
85
Tell me what the greater & lesser palatine nerves: 1) are a branch of 2) the fiber type they carry 3) and the structures they innervate
Greater & lesser palatine nerves 1) branch of CN V2 & CN VIII 2) fibers GSA & SVA 3) innervate the palate
86
Tell me what the nasopalatine nerve: 1) is a branch of 2) the fiber type it carries 3) and the structure(s) it innervate(s)
nasopalatine nerve 1) CN V2 2) GSA fibers 3) Anterior palate
87
Tell me what the superior alveolar nerve: 1) is a branch of 2) the fiber type it carries 3) and the structure(s) it innervate(s)
superior alveolar nerve 1) CN V2 2) GSA fibers 3) upper teeth
88
Tell me what the inferior alveolar nerve: 1) is a branch of 2) the fiber type it carries 3) and the structure(s) it innervate(s)
inf alveolar nerve 1) CN V3 2) GSA fibers 3) lower teeth
89
Tell me what the infraorbital nerve: 1) is a branch of 2) the fiber type it carries 3) and the structure(s) it innervate(s)
infraorbital nerve 1) CN V2 2) GSA fibers 3) upper lip
90
Tell me what the lingual N nerve: 1) is a branch of 2) the fiber type it carries 3) and the structure(s) it innervate(s)
lingual nerve 1) CN V3 2) GSA fibers 3) anterior 2/3 of tongue
91
Tell me what the chorda tympani nerve: 1) is a branch of 2) the fiber type it carries 3) and the structure(s) it innervate(s)
chorda tympani nerve 1) CN VII 2) SVA fibers 3) anterior 2/3 of tongue
92
Tell me what the glossopharyngeal nerve: 1) is a branch of 2) the fiber type it carries 3) and the structure(s) it innervate(s)
glossopharyngeal nerve 1) trick! its its own entity! CN IX!!! 2) GVA fibers & SVA 3) postior 2/3 of tongue
93
Tell me what the internal branch of superior laryngeal nerve: 1) is a branch of 2) the fiber type it carries 3) and the structure(s) it innervate(s)
internal branch of sup laryngeal nerve 1) CN X 2) GVA fibers & SVA 3) epiglottis
94
Tell me what the pharyngeal branch nerve: 1) is a branch of 2) the fiber type it carries 3) and the structure(s) it innervate(s)
pharyngeal branch nerve 1) CN X 2) SVE 3) pataglossus muscle
95
Tell me what the hypoglossal nerve: 1) is a branch of 2) the fiber type it carries 3) and the structure(s) it innervate(s)
hypoglossal nerve 1) trick cuz its itself CN XII 2) GVE 3) most tongue muscles?
96
Tell me what the hypoglossal nerve: 1) is a branch of 2) the fiber type it carries 3) and the structure(s) it innervate(s)
hypoglossal nerve 1) trick cuz its itself CN XII 2) GVE 3) most tongue muscles?
97
Tell me what the nerve to the mylohyoid: 1) is a branch of 2) the fiber type it carries 3) and the structure(s) it innervate(s)
nerve to the mylohyoid 1) CN V3 2) GVE 3) mylohyoid :) AND Ant belly of digastric
98
what CN provides sensory innervation to phryngeal mucosa?
CN IX
99
What CN provides motor innervation to pharyngeal constrictors?
CN X
100
superior cervical sympathetic ganglion is vasomotor
idk how to make a question out of this, so just know that
101
Pharynx wall is composed of (name 3 big parts)?
1. Buccopharyngeal fascia 2. Muscular layer 3. Mucus membrane
102
Describe the parts/muscles of the muscular layer of the pharynx
External - circular mm Internal - Longitudinal mm. -stylopharyngeus m -salpingopharyngeus m -palatopharyngeus m
103
tell me where gap 1 of pharyngeal constrictors is and what structures it holds?
Gap 1 - b/w skull & superior constrictors -access to levator veli palatine -pharyngotympanic tube -ascending palatine artery
104
tell me where gap 2 of pharyngeal constrictors is and what structures it holds?
Gap 2 - b/w superior & middle constrictors -stylopharyngeus -CN IX -stylohyoid ligament
105
tell me where gap 3 of pharyngeal constrictors is and what structures it holds?
Gap 3 - b/w middle & inferior constrictors -internal laryngeal N -superior laryngeal artery and vein
106
tell me where gap 4 of pharyngeal constrictors is and what structures it holds?
Gap 4 - trick question, its coming from between the inferior pharyngeal constrictors -recurrent laryngeal N -inferior laryngeal artery
107
What are the 3 structures of unpaired cartilage in the larynx?
thyroid cricoid epiglottic
108
What are the 3 sets of paired cartilage in the larynx?
arytenoid corniculate cuneiform
109
What makes up the glottis?
vocal folds & processes Rima glottidis
110
What muscles is responsible for moving the entire larynx? What is the difference between infrahyoid and suprahyoid? think related to movement
Extrinsic laryngeal muscles: -infrahyoid - depresses -suprahyoid - elevates
111
There are a lot of intrinsic laryngeal muscles, what do they do as a group?
move larynx components, after vocal folds/rima glottidis
112
What does the cricothyroid muscle do?
stretch/tense vocal ligaments
113
What does the thyroarytenoid move in the larynx/
relaxes the vocal ligament
114
What does the posterior cricoarytenoid muscle do?
abduct vocal folds
115
Lateral cricoarytenoid does what movement in the larynx
adduct vocal cords
116
What muscle relaxes the posterior vocal ligament while maintaining anterior tesion?
vocalis
117
where do the papatine tonsils sit? what innervates them? where do they get their blood supply from?
-sit b/w palatoglossal arch & palatopharyngeal arch -IN: lesser palatine n & CN IX blood supply: -palatine branch of ascending pharyngeal a. -ascending palatine branches/tonsillar branches of facial a. -dorsal lingual a. -lesser palatine a.
118
where do the palatine glands sit? what innervates them?
-sit deeeeep to the mucous on the hard/soft palate -IN: CN VII (GVE-P)
119
Describe the innervation of the hard palate (2 major branches but all that entails etc)
Greater palatine N --> IN's gingivae, mucous membrane, glands of the hard palate -GSA = CN V2 -GVE-P = CN VII Nasopalatine N --> IN's mucous membrane and ant. hard palate -GSA = CN V2 -SVA/GVE-P = CN VII
120
WHat is the blood supply of the hard palate?
descending palatine artery --> greater palatine artery -DP art branches at pterygopalatine canal -GP art exits at greater palatine foramen
121
What is the blood supply for the soft palate? What is it's IN?
-descending palatine art. --> lesser palatine art ANASTOMOSES to ascending palatine art -lesser palatine art exits at the lesser palatine foramen IN: lesser palatine N -gsa = cn V2 -SVA/GVE-P = CN VII (remember from gustatory pathway)
122
What type of epithelium is most prominent in pharyngeal and tubal structures?
respiratory epithelium
123
What type of epithelium/cells is most prominent in the palatine and lingual structures?
stratified squamous
124
KNow the IN to the larynx. I can't make questions out of this right now...
sorry