The process of spatial normalisation where indivuals data is transformed into a standardised space to allow data to be integrated across individuals who are anatomically variable
An atlas provides a guide to the location of anatomical structures in a co-ordinate space
A template is a representative of an image that provides a target to which individual images can be aligned.
Templates can be based from Talariach (a single 60 year old post mortem female brain) or MNI - the average of 152 scans from healthy young adults
Talariach requires land-mark based registration, whereas MNI is automated.
A structural image is normally taken and co-registered with functional images (incase individual has moved). Structural image is then normalised to the template and these parameters are applied to the functional data
where is the 0, 0, 0 co-ordinates of the MNI atlas?
The anterior commisure