Specific bacterial drugs Part 2 Flashcards

(56 cards)

1
Q

E. coli Serotype K1–Neonatal meningitis

A

ampicillin + 3rd generation cephalosporin

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2
Q

Invasive E. coli:

A

carbapenem
UTIs: fosfomycin, nitrofurantoin
Colistin (for carbapenem res. isolates

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3
Q

Typhoid Fever

A

Ciprofloxacin, levofloxacin
Asians: azithromycin, ceftriaxone
Critically ill: carbapenem, then de-escalate

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4
Q

Shigella

A

ciprofloxacin, levofloxacin (po or IV)
ceftriaxone (IV)
azithromycin (pediatric)

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5
Q

Yersinia enterocolitica

A

ceftriaxone

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6
Q

Yersinia pestis

A

gentamicin or streptomycin

PEP: doxycycline or cipfofloxacin

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7
Q

Klebsiella pneumoniae

A

cephalosporins or fluoroquinolones

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8
Q

Klebsiella granulomatis

A

doxycycline > 3 weeks

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9
Q

Cholera

A

rehydration therapy:
IV ringer’s lactate
Oral rehydration salts

single dose doxycycline
azithromycin (kids, pregnancy)

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10
Q

C. jejunni

A

azithromycin

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11
Q

life threatening campylobacter (usually C. fetus)

A

carbapenem, aminoglycoside

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12
Q

Gram - Anaerobes

A

metronidazole, carbapenem, beta-lactam plus inhibitor

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13
Q

propionibacterium

A

benzoyl peroxide

erythromycin

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14
Q

actinomyces

A

surgical debridement

penicillin

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15
Q

mobiluncus

T. vaginallis

A

metronidazole or clindamycin

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16
Q

Lactobacilli

A

penicillin + aminoglycoside

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17
Q

C. diff

A

metronidazole or vancomycin

discontinue associated antibiotic treatment

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18
Q

Francisella tularensis

A

gentamicin, tobramycin (streptomycin)

alternatives: doxycycline (all tick infections)

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19
Q

Syphillis

A

penicillin G (IM)

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20
Q

LBRF

A

Tetracycline

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21
Q

TBRF

A

Doxycycline

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22
Q

Leptospira

A

IV penicillin

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23
Q

Leptospira exposure

A

Oral doxycycline

24
Q

Helicobacter

A

PPI

sequential antibiotics: amoxicillin–>clarithroycin/levofloxacin + tinidazole

25
Pseudomonas aeruginosa
anti-pseudomonal beta-lactam + beta lactamase inhibitor + aminoglycoside
26
B. cepacia
TMP-SMX carbapenem fluoroquinolone
27
B. pseudomallei
IV cephalosporin/carbapenem followed by oral TMP-SMX + doxycycline
28
Moraxella
penicillin w/ beta-lactamase inhibitor susceptible to all other antibiotics used for respiratory therapy: macrolides, fluoroquinolones, tetracyclines
29
Invasive H. influenzae
3rd gen cephalosporins
30
H. influenzae otitis media, sinusitis
ampicillin cecphalosporin fluoroquinolone
31
B. pertussis
macrolides at early stages supportive measures after paroxysmal stage **prophylaxis to close contacts for 14 days regardless of age or vaccination status
32
Rickettsia
doxycycline
33
Coxiella burnetti (Q fever)
tetracyclines
34
Ehrlichia/Anaplasma
tetracycline
35
Trench Fever
erithromycin, gentamycin
36
Bacillary angiomatosis
erithromycin, gentamycin
37
Peliosis hepatis
erithromycin, gentamycin
38
Bartonella endocarditis
erithromycin, gentamycin
39
Cat Scratch Disease
None
40
Chlamydia trachoma
tetracycline
41
genital chlamydia
single dose azithromycin
42
N. gonorrhoeae and C. trachomatis co-infectin
ceftriaxone (IM) + azithromycin (po)
43
mycoplasma
tetracyclines, macrolides, fluoroquinolones
44
Legionella
macrolide or quinolone
45
Tularemia
gentamicin, tobramycin (streptomycin)
46
Brucella
gentamicin/rifampin + doxycycline
47
V. vulnificus
doxycycline or 3rd generation cephalosporin ( septic or compromised patients
48
V. parahaemolyticus
doxycycline + ceftriaxone (people with immunodeficiencies or liver disease
49
Acinetobacter
meropenem and amikacin (resistance developing)
50
Drugs associcated with Pseudomembranous Ccolitis
ampicillin, cephalosporins, clindamycin
51
C. perfringens
penicillin + clindamycin
52
C. pneumophila
azithromycin or levofloxacin
53
Lyme Prevention
doxycyline
54
Early Lyme Treatment
oral tetracycline (1 month)
55
Late Lyme Treatment
IV cephalosporin
56
Antibiotic-Refractory Post-Lyme
Anti-inflammatory agents