Specific bacterial drugs Part 2 Flashcards Preview

Question 1

1

E. coli Serotype K1--Neonatal meningitis

Answer

ampicillin + 3rd generation cephalosporin

Question 2

2

Invasive E. coli:

Answer

carbapenem
UTIs: fosfomycin, nitrofurantoin
Colistin (for carbapenem res. isolates

Question 3

3

Typhoid Fever

Answer

Ciprofloxacin, levofloxacin
Asians: azithromycin, ceftriaxone
Critically ill: carbapenem, then de-escalate

Question 4

4

Shigella

Answer

ciprofloxacin, levofloxacin (po or IV)
ceftriaxone (IV)
azithromycin (pediatric)

Question 5

5

Yersinia enterocolitica

Answer

ceftriaxone

Question 6

6

Yersinia pestis

Answer

gentamicin or streptomycin
PEP: doxycycline or cipfofloxacin

Question 7

7

Klebsiella pneumoniae

Answer

cephalosporins or fluoroquinolones

Question 8

8

Klebsiella granulomatis

Answer

doxycycline > 3 weeks

Question 9

9

Cholera

Answer

rehydration therapy:
IV ringer's lactate
Oral rehydration salts

single dose doxycycline
azithromycin (kids, pregnancy)

Question 10

10

C. jejunni

Answer

azithromycin

Question 11

11

life threatening campylobacter (usually C. fetus)

Answer

carbapenem, aminoglycoside

Question 12

12

Gram - Anaerobes

Answer

metronidazole, carbapenem, beta-lactam plus inhibitor

Question 13

13

propionibacterium

Answer

benzoyl peroxide
erythromycin

Question 14

14

actinomyces

Answer

surgical debridement
penicillin

Question 15

15

mobiluncus
T. vaginallis

Answer

metronidazole or clindamycin

Question 16

16

Lactobacilli

Answer

penicillin + aminoglycoside

Question 17

17

C. diff

Answer

metronidazole or vancomycin
discontinue associated antibiotic treatment

Question 18

18

Francisella tularensis

Answer

gentamicin, tobramycin (streptomycin)
alternatives: doxycycline (all tick infections)

Question 19

19

Syphillis

Answer

penicillin G (IM)

Question 20

20

LBRF

Answer

Tetracycline

Question 21

21

TBRF

Answer

Doxycycline

Question 22

22

Leptospira

Answer

IV penicillin

Question 23

23

Leptospira exposure

Answer

Oral doxycycline

Question 24

24

Helicobacter

Answer

PPI
sequential antibiotics: amoxicillin-->clarithroycin/levofloxacin + tinidazole

Question 25

25

Pseudomonas aeruginosa

Answer

anti-pseudomonal beta-lactam + beta lactamase inhibitor + aminoglycoside

Question 26

26

B. cepacia

Answer

TMP-SMX
carbapenem
fluoroquinolone

Question 27

27

B. pseudomallei

Answer

IV cephalosporin/carbapenem followed by oral TMP-SMX + doxycycline

Question 28

28

Moraxella

Answer

penicillin w/ beta-lactamase inhibitor

susceptible to all other antibiotics used for respiratory therapy: macrolides, fluoroquinolones, tetracyclines

Question 29

29

Invasive H. influenzae

Answer

3rd gen cephalosporins

Question 30

30

H. influenzae otitis media, sinusitis

Answer

ampicillin
cecphalosporin
fluoroquinolone

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