SPIROCHETES Flashcards

1
Q

SPIROCHETES motility

A

corkscrew

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2
Q

Organisms that can’t be visualize in brightfield microscopy

A

SPIROCHETES

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3
Q

SPIROCHETES are Motile because they produce

A

axial fibrils (flagella)

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4
Q

disease of blood vessels; sexually transmitted disease

A

Syphilis

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5
Q

turning threads

A

Treponema

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6
Q

Non-culturable on artificial media

A

Treponema pallidum

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7
Q

Treponema pallidum treatment

A

Penicillin - Jarisch-Herxheimer reaction

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8
Q

transplacental transmission of syphilis

A

Congenital Syphillis

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9
Q

Congenital Syphilis
○ Early stage is like the second stage or _______
○ Late stage is the latent stage or _______

A

condylomata
deadly

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10
Q

seen in children who had congenital syphilis (3)

A

Hutchinson triad
■ deafness
■ blindness
■ notched or pegged teeth

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11
Q

Clinical Infection of Syphilis
Primary Stage. (4)

A

Hard Chancre
- unitarian?
- genitalia dry lesions
- not painful

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12
Q

Clinical Infection of Syphilis
Secondary Stage (5)

A

Condylomata lata
- wart-like
- genitalia
- 6-8 weeks
- after dry lesions (hard chancre)

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13
Q

Clinical Infection of Syphilis
Latent Stage (3)

A

Asymptomatic
- hidden
- serological stage

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14
Q

Clinical Infection of Syphilis
Tertiary Stage (3)

A

Gumma’s
- deep organs
- neuro/cardiac syphilis

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15
Q

Syphilis Serological Tests

A

Non-Treponemal
Treponemal

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16
Q

sero test that is not specific for syphilis

A

Non-Treponemal

17
Q

specific test for syphilis

A

Treponema

18
Q

Non-Treponemal tests (3)

A

● VDRL
● RPR
● TRUST

19
Q

Treponemal tests (5)

A

● TPI
● TPHA
● MHA-TP
● FTA-ABS
● RPCF

20
Q

heated serum (waterbath); microscopic

A

VDRL

21
Q

RPR (4)

A

commonly used today;
neurosyphilis (CSF);
modified version of VDRL;
macroscopic

22
Q

most specific test for syphilis

A

FTA-ABS

23
Q

uses nonvirulent treponeme; nonreactive for late stage of syphilis

A

RPCF

24
Q

Yaw or Frambesia

A

T. pallidum subsp. pertenue

25
Q

Bejel

A

T. pallidum subsp. endemicum

26
Q

Carate or Pinta

A

T. pallidum subsp. carateum

27
Q

endemic syphilis

A

T. pallidum subsp. endemicum

28
Q

oldest human treponema

A

T. pallidum subsp. carateum

29
Q

● Transmitted thru flies
● crab feet/yaws
● Disease of bone, skin and joints

A

T. pallidum subsp. pertenue