Spongiotic Dermatitis Flashcards
1
Q
Spongiotic dermatitis aka
A
eczematous dermatitis
2
Q
Histologic ddx of spongiotic dermatitis
A
- allergic contact dermatitis
- atopic (eczematous) dermatitis
- drug and id/hypersensitivity reactions
- nummular dermatitis
- dyshidrotic dermatitis
- seborrheic dermatitis
3
Q
Spongiotic dermatitis with eosinophils
- Histologic findings
- DDX
A
Histologic findings:
- spongiosis
- eosinophils in dermis +/- epidermis
- Occasional vesicles
- PK
- acanthosis in subacute to chronic lesions
DDX:
- allergic contact dermatitis
- atopic eczema
- nummular eczema
- drug reactions (usually see interface also)
- Hypersensitivity/id reactions
- scabies
- arthropod bite (deep eos)
- seb derm (few eos)
- vesicular stage of incontinentia pigment
- urticarial stage of bullous pemphigoid
- viral exanthem
4
Q
A
Spongiotic dermatitis with eosinophils
5
Q
Dermatophytosis
A
Tinea infections
- Spongiosis
- Parakeratosis
- Sandwich sign (hyphae sandwiched between basketweave orthokeratosis above and compact ortho or parakeratosis below)
6
Q
A
Dermatophytosis (tinea)
7
Q
Pityriasis rosea (PR)
- Histology
- DDX
A
Histology
- Focal mounds of PK
- Acanthosis
- Spongiotic vesicles with lymphs
- RBC extravasation
DDX:
Subacute spongiotic dermatitis:
- eczematous and contact derm
- seb derm (face and scalp with perifollicular PK)
- pityriasis lichenoides
8
Q
A
Pityriasis rosea
9
Q
Mycosis Fungoides, patch stage
Histology
A
Usually not spongiotic, but may be mild
Epidermotropism
Cytologic atypia
Pautrier’s microabscesses
10
Q
A
Mycosis fungoides
11
Q
Incontientia pigmenti (IP)
- Histology
- DDX
A
Histology
- Eosinophilic spongiosis
- Dyskeratotic keratinocytes
DDX:
- eczematous dermatitis
- erythema toxicum neonatorum (no dyskeratosis)
12
Q
Neutrophilic spongiosis is found in
A
- Psoriasis
- Subcorneal pustular dermatosis (Sneddon Wilkinson disease)
- Acute generalized exanthematous pustulosis (AGEP)
- Dermatophytosis
- Bacterial infections
- Reiter’s syndrome
