Spring Quiz 7 Flashcards Preview

Top 200 Drugs PY2 > Spring Quiz 7 > Flashcards

Flashcards in Spring Quiz 7 Deck (24)
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1
Q

Trazodone (Brand, Class, MOA)

A

Oleptro. Antidepressant, Serotonin Reuptake Inhibitor/Antagonist. Inhibits reuptake of serotonin, causes adrenoreceptor subsensitivity, and induces significant changes in 5-HT presynaptic receptor adrenoreceptors.

2
Q

Trazodone (Indication, BBW, Preg)

A

Depression. Suicidal thoughts and behaviors. No.

3
Q

Vilazodone (Brand, Class, MOA)

A

Viibryd. Antidepressant, Serotonin Reuptake Inhibitor/Antagonist. Vilazodone inhibits CNS neuron serotonin uptake, It also binds selectively with high affinity to 5-HT1A receptors and is a 5-HT1A receptor partial agonist.

4
Q

Vilazodone (Indication, BBW, Preg)

A

Depression. Suicidal thoughts and behaviors. No.

5
Q

Mirtazapine (Brand, Class, MOA)

A

Remeron, Remeron Soltab. Alpha-2 Adrenergic Antagonist, Antidepressant. Central presynaptic alpha2-antagonist effects, which results in increased release of NE and 5HT.

6
Q

Mirtazapine (Indication, BBW, Preg)

A

Major depressive disorder. Suicidal thoughts and behaviors. No.

7
Q

Alprazolam (Brand, Class, MOA)

A

Xanax. Benzo. Enhancement of the inhibitory effect of GABA on neuronal excitability results by increased neuronal membrane permeability to Cl ions. This shift in Cl ions results in hyperpolarization (a less excitable state) and stabilization.

8
Q

Alprazolam (Indication, BBW, Preg)

A

Panic and anxiety disorder. No. No.

9
Q

Lorazepam (Brand, Class, MOA)

A

Ativan. Benzo. Enhancement of the inhibitory effect of GABA on neuronal excitability results by increased neuronal membrane permeability to chloride ions. This shift in chloride ions results in hyperpolarization (a less excitable state) and stabilization.

10
Q

Lorazepam (Indication, BBW, Preg)

A

Anxiety, status elipticus. No. No.

11
Q

Divalproex sodium (Brand, Class, MOA)

A

Depakote. Anticonvulsant. Causes increased availability of GABA, an inhibitory NT, to brain neurons or may enhance the action of GABA or mimic its action at postsynaptic receptor sites.

12
Q

Divalproex sodium (Indication, BBW, Preg)

A

Seizures. Increased risk of acute liver failure, hepatotoxicity, fetal risk, and pancreatitis. X.

13
Q

Carbamazepine (Brand, Class, MOA)

A

Tegretol. Anticonvulsant. Anticholinergic, antineuralgic, antidiuretic, muscle relaxant, antimanic, antidepressive, and antiarrhythmic properties

14
Q

Carbamazepine (Indication, BBW, Preg)

A

Seizures. Toxic epidermal necrolysis, Stevens-Johnson Syndrome, Aplastic anema and agranulocytosis. No.

15
Q

Lamotrigine (Brand, Class, MOA)

A

Lamictal. Anticonvulsant. Anticholinergic, antineuralgic, antidiuretic, muscle relaxant, antimanic, antidepressive, and antiarrhythmic properties.

16
Q

Lamotrigine (Indication, BBW, Preg)

A

Seizures. Toxic epidermal necrolysis, Stevens-Johnson Syndrome, Aplastic anema and agranulocytosis. No.

17
Q

Lithium (Brand, Class, MOA)

A

Lithobid. Antimanic agent. Unknown.

18
Q

Lithium (Indication, BBW, Preg)

A

Bipolar disorder. Lithium toxicity is closely related to serum lithium levels, and can occur at doses close to therapeutic levels. No.

19
Q

Phenytoin (Brand, Class, MOA)

A

Dilantin. Anticonvulsant, hydantoin. Stabilizes neuronal membranes and decreases seizure activity by increasing efflux or decreasing influx of Na ions across cell membranes in the motor cortex during generation of nerve impulses.

20
Q

Phenytoin (Indication, BBW, Preg)

A

Seizures. Cardiovascular risk associated with rapid infusion. No.

21
Q

Pregabalin Brand, Class, MOA)

A

Lyrica. Anticonvulsant, analgesic. Binds to alpha2-delta subunit of voltage-gated Ca channels within the CNS and modulates Ca influx at the nerve terminals, thereby inhibiting excitatory NT release including glutamate, NE, 5HT, DA, substance P, and calcitonin gene-related peptide.

22
Q

Pregabalin (Indication, BBW, Preg)

A

Neuropathic pain, seizures. No. No.

23
Q

Sumatriptan (Brand, Class, MOA)

A

Imitrex. Serotonin R agonist. Selective agonist for serotonin on intracranial blood vessels and sensory nerves of the trigeminal system; causes vasoconstriction and reduces neurogenic inflammation associated with antidromic neuronal transmission correlating with relief of migraine

24
Q

Sumatriptan (Indication, BBW, Preg)

A

Migraine. No. No.