Staable Angina Flashcards
(22 cards)
What is strangle angina
REVERSIBLE MI WITHOUT necrosis
Symptoms
Chest pain, can radiate to jaw, neck, shoulder,arms
Management of acute attacks
Sublingual GTN
Examples of short acting and long acting
Short - GTN
Long - isosorbride monotintrate
What is stage angina - what happens in the heart
Reversible ischemia NO necrosis
Occurs due to plaque build up reducing blood flow to the heart plus oxygen
What is used for immediate relief
sublingual GTN
What is the first line in regular treatment
BB (if CI - rate limiting CCB
What is the 2nd line in regular treatment
+ CCB
Do not add CCB to rate limiting CCB, their second line would be LA nitrate
What is the 3rd line in regular treatment
+ long acting nitrate
or
Ivabradine
Or
Nicorandil
Or
Ranolazine
If both CCB and BB are CI, what to give
Monotherapy of :
long acting nitrate (isosorbide mononitrate)
or
Ivabradine
Or
Nicorandil
Or
Ranolazine
If in first line BB cannot be given, what to give
Rate limiting CCB
Would should you never add to a CCB
A rate limiting CCB
BB and rate limiting should not be given together, why?
Bradycardia
As all patients with angina are assumed to be at high risk of of CVD events,
What to other classes ma of drugs should be added to their regimen (it’s also called secondary prevention, but it’s given to everyone
Antiplatlet
• 75mg aspirin/daily +
• statin
What other treatment should be given with those with diabeties
ACEI
Instead of aspirin, people with PAD and stroke will be on clopidogrel
Should this be changed
No
They can continue
What is all optimal medications don’t work
Revascularisation
• bypass graphing
• PCI
What are some complications of stage angina
Stroke
STEMI
NSTEMI
Which drug should never be given with nitrates and why
Phosphodiesterase inhibitors
• slidenafil
Why- causes hypotension
Ivabradine moa
Rate limiting
Inhibits funny channels in SA node
Nicorandil
Nitrate
K channel activator
Increases cGMP levels
Which drug can cause mucosal ulceration
Nicorandil