STAGES OF GRANULOCYTE DEVELOPMENT Flashcards

(45 cards)

1
Q

15-20

A

Myeloblast

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2
Q

15-21

A

Promyelocyte

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3
Q

12-18

A

Myelocyte

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4
Q

10-15

A

Metamyelocyte

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5
Q

9-15

A

Band (Stab or Staff Cell)
Segmented Neutrophils
Eosinophil

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6
Q

10-16

A

Basophil

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7
Q

Basophilic & scanty non-granular

A

Myeloblast

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8
Q

Basophilic & abundant

A

Promyelocyte

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9
Q

Primary granules start to appear

A

Promyelocyte

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10
Q

moderate amount w/ few specific granules

A

Myelocyte

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11
Q

Secondary granules start to appear

A

Myelocyte

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12
Q

Moderate to abundant w/ Specific granules (N, E, B) - insignificant cytoplasm

A

Metamyelocyte

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13
Q

Specific granules

A

Band

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14
Q

grainy cytoplasm (pink/rose-pink violet granules)

A

Segmented Neutrophils

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15
Q

red-orange refractile granules

A

Eosinophil

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16
Q

Sp. Granules contain histaminase (anti-parasitic), peroxidase (cyanide resistant), B-glucuronidase, arysulfatase, acid phosphatase (ACP), phospholipase, ribonuclease & cathepsin

A

Eosinophil

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17
Q

with few, large, densely-stained, dark purple to blue-black granules

A

Basophil

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18
Q

Granules contain heparin, Serotonin, peroxidase, histamine

A

Basophil

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19
Q

NUCLEOLI: 2-5

20
Q

NUCLEOLI: 2-3

21
Q

NUCLEOLI: 3-4

A

Segmented Neutrophils

22
Q

(+) Non-Sp. Esterase, Peroxidase, & Sudan B

23
Q

Counted w/ CBC

24
Q

Counter part: Retics

25
Thick w/o filament formation
Band
26
Larger than RBC
Segmented Neutrophils
27
Similar to band
Eosinophil
28
Romanowsky Stain - stains early myelocytes to determine early maturation)
Eosinophil
29
- primarily in allergic rx
Basophil
30
Round or slightly oval Fine chromatin
Myeloblast
31
Oval to round Slightly coarser chromatin pattern
Promyelocyte
32
Oval to round Coarse chromatin
Myelocyte
33
Indented/kidney-bean shaped
Metamyelocyte
34
Coarse & clumped chromatin
Metamyelocyte Band Segmented Neutrophils Eosinophil
35
Elongated or band-shaped
Band
36
Usually band or bilobed
Eosinophil
37
round, indented, band or bilobed w/ smudged chromatin pattern
Basophil
38
hypersensitivity - excessive release of granules causing VASOCONSTRICTION
histamine
39
stimulates chemotaxis
chemotactic factor a
40
CFU-baso
Basophil
41
Basophil Life span: [?] (bone marrow); [?] (circulation); [?] (tissue)
7 days, 16 hrs, 9-18 months
42
Similar to macrophage
Basophil
43
Basophil: [?] (principal growth factor for baso dev't) [?] [?] (stimulates baso dev't)
IL-3 IL-5 CSF-GM
44
Primarily in allergic rx
Basophil
45
Water-soluble
Basophil