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Flashcards in Statins Deck (7):
1

Indications

1. Primary prevention of cardiovascular disease

2. Secondary prevention of cardiovascular disease

3. Primary hyperlipidaemia

2

Mechanism of action

Inhibition of HMG CoA reductase - enzyme involved in making cholesterol

3

Adverse effects

Headache
GI disturbances

4

Warnings

Use caution in hepatic impairment

Reduce dose in renal impairment

5

Interactions

Avoid concurrent use of macrolides or other P450 inhibitors

6

Prescribing

PO

7

Administration

Usually taken in evening