Steroids

Question 1

3 categories of steroids

Answer 1

Mineralochoirticoids, Glucocorticoids, Sex Steroids

Question 2

Mineralocorticoids Function

Answer 2

Promote sodium reabsorption by transporting epithelia of kidneys, salivary glands and large intestine

Question 3

Glucocorticoids Functions

Answer 3

Stimulates gluconeogenesis, anti0inflammatory and immunosuppressive effects

Question 4

Glucocorticoids Anti-inflammatory effects

Answer 4

Low doses for anti-inflammatory effects
1) decrease swelling after sprains, strains
2) decrease respiratory inflammation
3) help allergic reactions and skin conditions

Question 5

Glucocorticoids immunosuppressive effects

Answer 5

High doses for immunosuppressive effects
1) helps immune related diseases (MS, kidney disease)
2) helps keep body’s response to organ transplants in check

Question 6

Sex steroids function

Answer 6

1 Influence maintenance and growth of muscles
2) Regulate sexual differentiation
3) Regulate secondary sex characteristics
4) Regulate sexual behaviours & reproduction

Question 7

Negative effects of glucocorticoids

Answer 7

1) Increased chance of infection
2) Increased fat and protein breakdown
3) abortion

Question 8

Why can’t you stop glucocorticoids abruptly

Answer 8

It will suppress the HPA axis

Question 9

Difference between slow vs fast stress response

Answer 9

Slow stress response is mediated by the HPA axis, fast stress response is mediated by the SAM axis