STIs Flashcards
(25 cards)
What is the most common STI in the UK?
Chlamydia
In which populations group is diagnosis of chlamydia highest?
Women aged 15 - 24
Which STI is the most likely cause of urethritis in males?
Which epithelium does it infect?
Gonorrhoea
Columnar epithelium of urethra
BV is due to the overgrowth of what?
Anaerobic bacteria
Which STI is the most likely cause of ulcerative genital lesions?
Herpes
Which pathology involves inflammation from the epididymis extending to testes?
Epididymo-orchitis
Which STI causes genital warts?
HPV
Which type of epithelial cells does gonorrhoea infect?
Columnar epithelial cells
How does gonorrhoea attach?
Via pili
Where is the primary site of infection of gonorrhoea in females?
Cervix
When do symptoms of gonorrhoea develop?
2-14 days post-infection but often asymptomatic in females (50%)
Where is the primary site of infection of chlamydia in females?
Endocervix
What are the 2 forms of chlamydia?
Elementary body
Reticulate body
Elementary body chlamydia is adapted for survival in which kind of environment?
Extracellular
Reticulate body chlamydia is adapted for survival in which kind of environment?
Intracellular
What are the 3 stages of syphilis?
Primary - 21 days
Secondary - 3 - 10 weeks
Tertiary - 20 - 40 years
Primary syphilis causes which kind of lesions?
Chancre lesions
Secondary syphilis causes which 2 kinds of lesions?
Cutaneous
Mucocutaneous
Which growth occurs at the tertiary stage of syphilis?
Gumma
What are the 4 elements of herpes virus?
Core
Capsid
Tegument
Glycoproteins
What is the test of choice for gonorrhoea?
Nucleic acid amplification test (NAAT)
What is the test of choice for syphilis?
Serology (antibody detection)
What is the treatment for gonorrhoea?
Ciprofloxacin / ceftriaxone
What is the treatment for chlamydia?
Doxycycline