Stress Flashcards
(107 cards)
General adaptation syndrome (GAS)
Stage 1: alarm reaction
- A threat/ stressor is recognised + a response is made
- The hypothalamus triggers the sympathetic nervous system which activates the adrenal medulla to screte adrenaline + nor-adrenaline
- The body is in a ‘fight or flight’ respnse
Stage 2: resistance
- If the stressor continues then it is necessary to find a way of coping with it
- The body is adapting to the demands of the environment but at the same time resources are gradually being depleted
- Levels of cortisol are increased in blood sugar
- While the body appears to be coping physiologically speaking things are deteriorating (e.g. immune system becoming less effective
Stage 3: Exhaustion
- Eventaully the bodys systems can no longer maintain normal functioning
- At this point the initial symptoms of the adrenal response may reappear (absent from stage 2) e.g. raised heart rate
- The adrenal glands may be damaged from previous overuse + the immune system may not be able to cope because the production of necessary protines has been slowed in favour of other needs
- The result of this may be seen in stress related illnesses e.g. ulcers, depression, cardiovascular problems + other mental + physical illnesses
General adaptation syndrome (GAS) research
Selye:
− Selye’s model was based on his observations working with human patients – he noticed that they all shared a common set of symptoms, aches + pains, loss of appetite etc. no matter what was wrong with them
− He investigates this using rats
− He caused surgical injury, injected them with noxious substances, excessive exercise + temperature change
− He found that regardless of the stressor the response was the same – enlargement of the adrenal gland, shrinkage of the thymus, spleen + lymph glands + ulcers in the stomach + small intestine
− This suggests that there is one bodily response – supporting the GAS
Timio et al:
− Spent 20 yrs. comparing nuns (protected from everyday stresors) with working women (who were not)
− Found that the nuns blood pressure was unchanged while women working had heightened blood pressure
− This supports the notion that long term stress has negative effects on physical health – this is in line with the GAS
Evaluation of the General adaptation syndrome (GAS): animal research
− Much of Selye’s initial research was conducted on rats who may not respond to stress in the same way as humans e.g. rats are more passive in their response where as humans often actively try to find ways to lessen the stressor, therefore the response may not be the same as humans meaning that there is difficulty in generalising the findings
Evaluation of the General adaptation syndrome (GAS): Unethical
− Furthermore Selye’s research was highly unethical – many believed the stress inflicted on the rats was unacceptable, Selye thought this was justified as he hoped they would lead to therapeutic breakthroughs in treating stress related illnesses
Evaluation of the General adaptation syndrome (GAS): Individual differences
− Selye failed to recognise individual differences in stress responses:
→ Mason showed that stressors all vary in the amount of stress hormones (adrenaline + cortisol) that they produce depending on the amount of fear/anger created, there are also gender differences in stress responses (e.g. tend/befriend in females) therefore it is unlikely we all go through the exact same stress response
The sympathomedullary pathway (SAM axis)
- Immediate (acute) stressors arouse the sympathetic branch of the autonomic nervous system
- The hypothalamus detects stress
- Activates the sympathetic branch of the autonomic nervous system (ANS)
- Triggers the adrenal medulla
- Releases adrenaline + nor-adrenaline
− Release of adrenaline results in quickening of heart rate + breathing, it also slows down digestion to conserve recourses for fight or flight
− The parasympathetic branch of the ANS returns heart rate + blood pressure to normal as well as speeding up digestion causing the body to relax
The hypothalamic pituitary-adrenal system (HPA axis)
- If stress continues (chronic) then the hypothalamic pituitary-adrenal system is increasingly activated
- The hypothalamus detects stress + releases corticoprophin releasing factor (CRF/CRH)
- The pituitary gland secretes adrenal-corticotropic hormone (ACTH)
- Travels to the adrenal context
- Releases corticosteriods (e.g. cortisol) into the blood stream
− Cortisol maintains a steady supply of blood sugar for continued energy which enables the body to cope with the stressor
− Cortisol release increases the ability to tolerate more pain BUT can impair cognitive ability + reduce immune system performance
The role of cortisol
− Cortisol is secreted as a result of prolonged chronic stress in the HPA
− Cortisol permits a steady supply of blood sugar providing individuals with a constant supply of energy this allows the body to deal with stress
− Positive effects: individuals can tolerate more pain
− Negative impact:
→ Impaired cognitive ability
→ Cardiovascular system – dysfunctions of heart + blood vessels
→ Immune system – impaired ability to fight illness + disease
→ Weight – prolonged activation of the HPA system can lead to cushings syndrome which produces weight gain
The role of cortisol research
− Ppts given levels of cortisol high enough to produce blood sugar levels similar to those of people experiencing major stress events (e.g. abdominal surgery) were poorer at recalling prose passages than ppts given levels of cortisol only high enough to produce a stress reaction similar to having minor surgery (e.g. having stiches out)
− Suggests the HPA system can have a negative impact on memory
Evaluation of SAM + HPA: Scientific
P: Scientific
E: The biological explanation of stress allows accurate, objective measures to be made
E: People who have had their adrenal glands removed have to be given hormone supplements to help them cope with stressors highlighting the importance of the SMP, HPA system + stress hormones in responding to stress
Evaluation of SAM + HPA: Gender differences
P: Taylor et al (2000) suggest that, for females, behavioural responses to stress are characterised by a pattern of tend and befriend rather than fight or flight.
E: This involves protecting themselves and their young through nurturing behaviours (tending) and forming protective alliances with other women (befriending). Women may have a completely different system for coping with stress because their responses evolved in the context of being the primary caregiver of their children. Fleeing too readily at any sign of danger would put a female’s offspring at risk.
E: Oxytocin is thought to inhibit fight-or-flight response in females + promote relaxation + nurturing behaviours
C: Therefore the standard description of the HPA + SAM systems are arguably gender-biased (towards the male stress response) + not applicable to females particularly as studies on human stress responses have mainly been conducted on males – researchers were concerned that fluctuations in hormone levels as a result of the menstrual cycle could act as a confounding variable leading to varied stress responses thus reducing the validity of the data
Evaluation of SAM + HPA: Animal research
P: The use of animals in stress research – most of the research into the sympathomedullary pathway is animal-based.
E: The stress related behaviour of animals might not represent the stress related behaviour of humans. Humans are more likely to have a cognitive (thinking) element to their stress response e.g. to think about what is happening to them and consider options.
Evaluation of SAM + HPA: The role of cognitive factors
P: The role of cognitive factors in stress responses
- Research suggests that cognitive appraisal of a situation is crucial in terms of how the individual responds and ultimately determines how the body responds i.e. the individual’s thoughts (cognitive) and their interpretation of the situation will determine whether there is a physiological response or not.
- Lazarus and Folkman (1984) developed the transactional model to explain the role of cognitive appraisal in stress responses, explaining how an individual’s assessment of the demands of the situation (‘perceived demands’) and their perceived ability to cope determine whether or not the sympathomeduallary pathway is activated.
- If there is a mismatch between the perceived demands and the individual’s perceived ability to cope, then the sympathomedullary pathway is more likely to be activated.
- Symington et al. (1955) found that conscious terminal cancer patients experienced more (chronic) stress than those in a coma as they indulged in a more stressful appraisal of their condition, therefore demonstrating the role of cognitions.
The role of stress in illness - immunosuppression
− The immune system is our main defence against infection, seeking out and destroying foreign agents / antigens (bacteria, viruses, fungi)
− White blood cells are crucial to the functioning of the immune system + in the body’s fight against bacteria, virus + fungi
− Immunosuppression – weakening of the immune system making the body more prone to infection
− Corticosteroids (cortisol) produced as a result of chronic stress can shrink the thymus gland, preventing the growth of T cells (type of white blood cells)
The role of stress in illness - immunosuppression research: Kiecolt-Glaser et al. (1984) – NK cell activity
− Procedure:
→ Natural experiment
→ Ppts. – 75 medical students (doing final exams)
→ Natural killer cell (NK cell) activity was assessed in two blood samples, on taken one months before their final exams (low stress) + during their exams (high stress)
→ Ppts. also completed a questionnaire about life events + loneliness
− Findings:
→ NK cell activity was sig. lower in the second blood sample taken during exams compared to one month previous
→ NK cell was lowest amongst those who reported high levels life events + loneliness
− Conclusion:
→ Exam stress results in immunosuppression making individuals more susceptible to illness + infection
→ Immune functioning is also affected by psychological variables e.g. life events + loneliness which may make individuals more vulnerable to short term stressors e.g. exams
The role of stress in illness - immunosuppression research: Kiecolt-Glaser et al. (1995) – Wound healing in carers
− Procedure:
→ Ppts. – 13 women who cared for relatives suffering from senile dementia, a task associated with chronic stress + a matched control group of 13 women
→ All ppts. were given a ‘punch biopsy’
→ Ppts. were also assessed in terms of levels of cytokines (a substance that regulate the body’s immune system)
→ Ppts. also completed a stress scale
− Findings:
→ Wound healing took sig. longer in the carers than the control, it took an average of 9 days (24%) longer in the carers
→ Cytokine levels were found to be lower in the carers than the control
→ On the perceived stress scale the carers did actually indicate that they were feeling more stressed
− Conclusion: Chronic stress supresses immune system functioning
Evaluation of immunosuppression (the role of stress in illness): Stress may improve immunes system functioning
− The effects of stress may sometimes enhance immune system functioning:
→ Evans et al. looked at the activity of one particular antibody sigA which helps protect against infection, the researchers arranged for students to give talks to other students (an acutely stressful activity) levels of sigA were measured before giving these talks + during the exam period which lasted for many weeks – found that levels of sigA in the students rose before giving the mildly stressful talk but decreased during the exam period
→ Findings were supported by Segerstrom + Miller who carried out a meta-analysis of almost 300 studies of stress + the immune system + found that short term stressors promoted the body’s ability to fight infection however the longer the stress persisted the more likely the immune system was to shift to potentially detrimental changes
Evaluation of immunosuppression (the role of stress in illness): Difficult to establish a relationship
− It is difficult to establish a relationship between stress + illness (Lazarus) because:
→ Heath is affected by many different factors besides stress e.g. life style factors (diet, exercise, smoking, drinking, sleeping habits etc.)
→ Health is generally fairly stable + slow to change making it difficult to demonstrate that exposure to certain stressors cause a change in health
→ The long term study of stress would be expensive, time consuming + impractical
Evaluation of immunosuppression (the role of stress in illness): Individual differences
− Individual difference – research has also suggested that there are age + gender difference in the effects of stress on the immune system:
→ Kiecolt-Glaser found that females show several hormonal immune system changes in response to marital conflict
→ Segerstrom + Miller found that as people age stress has greater effect on immune system functioning making it harder for the body to regulate itself
→ Oher research has also suggested that personality type can determine the impact that stress has on immune system functioning e.g. those with a type A personality are more likely to experience the negative effects of stress
Evaluation of immunosuppression (the role of stress in illness): Correlational
Correlational
The role of stress in illness - cardiovascular disorder
− As well as resulting in a supressed immune system prolonged stress can also result in cardiovascular disorder’s (CVD)
− CVD: hardened arteries, hypertension (high blood pressure) + coronary heart disease (CHD) – arteries supplying the heart with blood becomes clogged up with fatty materials
− Stress activates the sympathetic branch of the ANS resulting in secretion of adrenaline, having the effects on:
→ Heart rate – increased heart rate causes the heart to work harder + takes a toll over time
→ Blood pressure – constriction of the blood vessels increases blood pressure which puts tension on vessels causing them to ware away
→ Blood vessels – increased pressure can also dislodge plaques on the walls of blood vessels + this leads to blocked arteries (atherosclerosis) this may cause a heart attack or stroke
− Stress may also indirectly lead to cardiovascular disorders through altered life style factors as a result of chronic stress e.g. smoking, poor diet, alcohol consumption, sedentary lifestyle, lack of exercise
The role of stress in illness - cardiovascular disorder research
− Aim: To investigate the relationship between anger + heart disease
− Procedure: Approx. 13,000 ppts. completed a 10 question anger scale which asked questions about levels of hot headedness, if they felt like hitting someone when angry, or whether they got annoyed when not given recognition for doing good work (none of the ppts. suffered from heart disease on the outset of the study) 6 yrs. later their health was assessed
− Findings:
→ 256/13,000 ppts. had experienced heart attacks
→ Those who had achieved the highest scores on the anger scale were over 2½ x more likely to have had a heart attack than those with the lowest angry ratings
→ Ppts. who achieved a ‘moderate’ score on the anger scale were 36% more likely to experience a coronary event than those with lower ratings
− Conclusion: This research suggests that sympathetic nervous system (SNS) activity is closely related to cardiovascular disorders
Evaluation of cardiovascular disorder (the role of stress in illness): Correlational
− Most of the research into stress + cardiovascular disorders is correlational – it is likely to be the case that the direct effects of stress combine with indirect effects in terms of life style choices, Cohen + Williamson found that chronic stress resulted in increased smoking + alcohol consumption as well as decreased levels of exercise + sleep deprivation
Evaluation of cardiovascular disorder (the role of stress in illness): individual differences
− Despite the apparent relationship bet. stress + cardiovascular disorders individual differences e.g. personality, age + gender have a part to play in terms of determining levels of vulnerability to developing CVDs through exposure to prolonged stress
→ E.g. research has found that the sympathetic branch of the ANS is more reactive in some individuals than others, these hypersensitive individuals therefore respond to stress with greater increases in blood pressure + heart rate leading to more damage to the cardiovascular system
→ Vaccarino exposed 49 female + male post heart attack patients to an acute stressor, found that females under 50 had twice the levels of myocardial ischaemia (when blood flow to your heart is reduced) than similar males – suggests that younger women are more at risk of CVDs through emotional stress