Stroke Flashcards

(32 cards)

1
Q

What is the definition of a stroke?

A

Clinical syndrome of vascular origin characterised by rapidly developing signs of focal or global cerebral dysfunction, lasting over 24 hours.

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2
Q

What is a transient ischaemic attack (TIA)?

A

< 24 hours of neurological dysfunction caused by focal brain, spinal cord or retinal ischaemia, without infarction.

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3
Q

What proportion of strokes are ischaemic?

A

80%

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4
Q

What are the main causes of ischaemic stroke?

A
  • Atherosclerosis (most common)
  • Embolic (e.g. AF causing embolus, thrombus)
  • Dissection.
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5
Q

What proportion of strokes are haemorrhagic?

A

20%

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6
Q

What are the main causes of haemorrhagic stroke?

A
  • Uncontrolled hypertension (most common)
  • Anticoagulation
  • Ruptured aneurysm
  • Trauma/falls.
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7
Q

List risk factors for stroke.

A
  • Previous stroke/TIA
  • Atrial fibrillation,
  • Carotid artery stenosis
  • Hypertension
  • Diabetes
  • Raised cholesterol
  • Family history
  • Smoking
  • Obesity
  • Vasculitis
  • Thrombophilia
  • COCP in smokers/migraine with aura.
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8
Q

What are the typical features of TIA?

A

Rapid onset, Most resolve within 1 hour.

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9
Q

What is capsular warning syndrome?

A

TIA affecting capsule
- over 3 episodes of sensory/motor sx
- Increased risk of stroke within 7 days

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10
Q

What are common features of stroke presentation?

A

Sudden onset:
* Unilateral limb or facial weakness
* Dysphasia
* Visual defects
* Sensory loss
* Ataxia and vertigo (posterior circulation).

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11
Q

How does UMN facial weakness present in stroke?

A

Facial weakness with sparing of the frontalis muscle.

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12
Q

What is Broca’s aphasia?

A

Non-fluent, expressive aphasia – patients understand language but struggle to speak.

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13
Q

What is Wernicke’s aphasia?

A

Fluent but meaningless speech – patients speak gibberish and can’t comprehend language.

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14
Q

What is a TACS?

A

Total anterior circulation stroke (proximal MCA/ICA)

with:
2 cortical dysfunctions (e.g. dysphasia, visual neglect)
+ Homonymous hemianopia
+ hemiparesis

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15
Q

What is a PACS?

A

Partial anterior circulation stroke (branch MCA)

with: 1 cortical dysfunction
1 motor/sensory deficit.

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16
Q

What is a LACS?

A

Lacunar stroke (small vessel, e.g. lenticulostriate branches)

with: Pure motor, Pure sensory, Mixed motor and sensory
No cortical dysfunction.

17
Q

What is a POCS?

A

Posterior circulation stroke (vertebral, basilar, cerebellar, PCA)

with: Visual impairment, Cerebellar signs.

18
Q

cerebellar signs

A

D - dysdiadocokinesia
A - ataxia
N - nystagmus
I - intention tremor
S - slurred speech
H - hypotonia

19
Q

What are some common stroke mimics?

A

Hypoglycaemia
Sepsis
Drug/alcohol intoxication
Syncope
Migraine with aura
Focal seizures
MS
Bell’s palsy
Functional neurological syndrome
Encephalitis
Hypertensive/Wernicke’s encephalopathy
space-occupying lesions.

20
Q

What imaging is used in suspected stroke?

A

Non-contrast CT - look at parenchyma
CT angiography of brain - Haemorrhage
Carotid imaging (USS/CT/MRI angio),
Diffusion-weighted MRI for TIA.

21
Q

What cardiac investigations are done in stroke?

A
  • ECG/24hr tape (for AF),
  • Echocardiogram (e.g. HFrEF).
22
Q

What blood and vascular tests might be done?

A
  • Thrombophilia screen,
  • Angiography.
23
Q

What are common complications of stroke?

A
  • Continence issues
  • Fatigue
  • Swallowing problems (aspiration pneumonia, nutrition, hydration)
  • Hearing and cognitive dysfunction,
  • Depression
  • Pain (neuropathic/MSK)
  • ADL and mobility issues (pressure sores, infections, VTE, constipation)
  • Recurrent stroke
  • Raised ICP.
24
Q

Which professionals are part of the stroke MDT?

A
  • Stroke team
  • Nurses
  • SALT, Dieticians
  • PT/OT
  • Social services
  • Optometry
  • Psychology
  • Orthotics.
25
How is TIA managed?
- Aspirin 300mg immediately - Specialist assessment within 24hrs - Diffusion-weighted MRI.
26
What is the first step in stroke management?
Exclude hypoglycaemia and do immediate CT brain to rule out haemorrhage.
27
How is haemorrhagic stroke managed?
- Aggressive BP control - Stop anticoagulants - Treat underlying cause (e.g. surgical clipping for aneurysm).
28
How is ischaemic stroke managed acutely?
- Aspirin 300mg daily for 2 weeks - Admission to stroke unit - Thrombolysis with Tenecteplase/alteplase (within 4.5hrs) - Thrombectomy (if large vessel occlusion, within 24hrs).
29
Contraindications of thrombolysis
- Hypoglycaemia - Low platelet count - Seizure with stroke - Stroke within last 3months - Symptoms suggesting SAH - Over 4.5hrs after stroke (may still benefit though)
30
What are long-term interventions in stroke management?
Carotid endarterectomy Angioplasty/stentin Anticoagulation for AF Secondary prevention: Clopidogrel 75mg (or Aspirin 75mg), Atorvastatin 20–80mg, BP/diabetes control.
31
Indications for mechanical thrombectomy
1. confirmed Large artery occlusion (proximal anterior circulation/posterior circulation) 2. within 6hrs of sx 3. potential to salvage brain tissue
32
How long must you stop driving after a stroke?
1 month if no residual symptoms.