Stroke Flashcards

(44 cards)

1
Q

What is the 3rd most common cause of death in the US?

A

Stroke

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2
Q

What is a stroke?

A

Sudden onset neurological deficit from the death of brain tissue

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3
Q

What are common causes of stroke?

A

sudden blockage in the flow of blood to the brain
Bleeding

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4
Q

Where do Emboli commonly originate in Strokes?

A

Carotid stenosis
Heart: A-Fib, Valvule disease, DVT through PFO

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5
Q

What are the common risk factors for stroke?

A

Hypertension, Diabetes, Hyperlipidemia, tobacco smoking

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6
Q

What artery is most commonly involved in stroke?

A

Middle Cerebral Artery (MCA)

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7
Q

How does a Middle Cerebral Artery (MCA) stroke present?

A

Weakness of sensory loss: Contralateral

Homonymous Hemianopsia: Loss of visual field opposite of stroke
-L MCA stoke causes loss or R visual fields

Aphasia: If ipsilateral to speech center (usually left)

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8
Q

How does an Anterior Cerebral Artery (ACA) stroke present?

A

Personality/cognitive defects: Confusion

Urinary Incontinence

Leg weakness

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9
Q

How does a Posterior Cerebral Artery (PCA) Stroke present?

A

Ipsilateral loss of the face, 9th and 10th CN

Contralateral sensory loss of limbs

Limb ataxia

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10
Q

What is the best initial test in suspected stroke?

A

CT Head W/o contrast

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11
Q

What is the most accurate test in suspected stroke?

A

MRI

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12
Q

Why is CT W/o Contrast done first in suspected stroke?

A

To exclude hemorrhage

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13
Q

What tests are used to help determine the cause and treatment for stroke?

A

Echocardiogram
EKG
Holte Monitor
Carotid Duplex Ultrasound

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14
Q

What is an Echocardiogram used to detect in stroke?

A

Surgical Replacement or repair of damaged valves

Patent Foramen Ovale (PFO)

Thrombi: anticoagulation

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15
Q

What is EKG used to detect in stroke?

A

A-Fib or A-Flutter: treat with DOAC or warfarin as long as the arrhythmia is present

Stroke or TIA means CHADS-VASc of 2 or more

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16
Q

What is a Holter monitor used to detect in stroke?

A

Atrial Arrhythmias if EKF is normal

if (-) long term monitor with loop recorder to find arrhythmia

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17
Q

What is Carotid Duplex US used to detect in stroke?

A

Carotid stenosis: Endarterectomy is superior
-if 100% stenotic: no intervention surgically

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18
Q

How do you treat a Hemorrhagic Stroke?

A

No treatment: surgical draining does not help the outside posterior fossa

19
Q

How do you treat a Nonhemorrhagic stroke <3 hours since onset?

A

thrombolytics

20
Q

How do you treat a nonhemorrhagic stroke >3 hours since onset?

A

Some get thrombolytics up to 4.5 hours
Aspirin
Dipyridamole or Clopidogrel: if already on aspirin at time of stroke

21
Q

What patients can receive Thrombolytics up to 4.5 hours after a stroke?

A

Age <80
NIH stroke scale <25
No hx of DM with previous stroke
No current use of anticoagulants

22
Q

What is the best treatment if it has been >4.5 hours since the onset of stroke?

A

Clot removal via catheter: useful for up to 24 hours

23
Q

What drug should be given to all stroke patients?

A

Statin: regardless of LDL to goal of <70

24
Q

What is Closure of a Patent Foramen Ovale (PFO) indicated in stroke patients?

A

Right to Left shunt detectable by bubble study

Embolic-appearing cryptogenic ischemic stroke

25
What common adverse effect is associated with thrombolytic use?
Angioedema
26
What is performed in stroke patients after thrombolytics?
Cerebral Catheterization: checking for residual clot to remove
27
What is the most common cause of a Subarachnoid Hemorrhage (SAH)?
Rupture of an aneurysm: usually in the anterior portion of the circle of willis
28
What conditions are cerebral aneurysms more common with?
Polycystic Kidney Disease Tobacco smoking Hypertension Hyperlipidemia High Alcohol Consumption
29
How does a Subarachnoid Hemorrhage typically present?
Sudden onset of extremely severe headache with meningeal irritation (stiff neck, photophobia and fever) Loss of conscious common
30
What causes the fever in Subarachnoid Hemorrhage?
Blood irritation of the meninges
31
What causes Loss of Consciousness in Subarachnoid Hemorrhage?
Sudden increase in Intracranial Pressure
32
What is the best initial test for SAH?
CT head W/o contrast
33
What is the most accurate test for SAH?
Lumbar Puncture (LP) showing blood -Xanthocromia: yellow CSF from breakdown of RBC -increased WBC with normal ratio of WBC:RBC
34
What is angiogram used for in SAH?
Determine the site of the aneurysm
35
What can be seen on EKG In SAH?
Large or inverted T-waves suggestive of Myocardial Ischemia
36
What are the treatment options for SAH?
Nimodipine (CCB) Embolization Ventriculoperitoneal Shunt Seizure Prophylaxis
37
What is role of Nimodipine (CCB) in SAH?
Prevent subsequent Ischemic stroke from vasospasm
38
What is role of a VP shunt in SAH?
SAH is associated with hydrocephalus: Only place shunt if hydrocephalus develops
39
What is the most common complication 24 hours after SAH treatment?
Re-bleeding
40
What is the most common complication 3-5 days after SAH treatment?
Vasospasm and stroke
41
How does Cerebral Vein Thrombosis present?
Mimics SAH: Clotting in cerebral veins, Headache over a couple of days, Possible weakness and speech difficulty, Normal LP
42
What are common risk factors for Cerebral Vein Thrombosis?
Malignancy, Thrombophilia, OCP use
43
What is the most accurate test for Cerebral Vein thrombosis?
Magnetic Resonance Venography (MRV)
44
How do you treat Cerebral Vein Thrombosis?
LMWH followed by Warfarin or DOAC