Structural & Functional Orginization of the Endocrine System Flashcards

1
Q

what are the major glands of the endocrine system

A

Thyroid

Hypothalamus

Pituitary

Parathyroid

Ovaries & Testes

Pancreas

Pineal Gland

Adrenals

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2
Q

what is a specific cell with a specific receptors that will respond to specific hormones

A

Target cells

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3
Q

how many receptors will a target cell have for a particular hormone

A

2,000 to 100,000

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4
Q

hormones are divided into what to what two categories

A

lipid soluble

water soluble

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5
Q

what are the lipid soluble hormones

A

Steroid hormones

thyroid hormones

Nitric Oxide

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6
Q

what are the water soluble hormones

A

Amino Acids

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7
Q

Amino Acids are subdivided into what two categories

A

Short chain

Long Chain

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8
Q

what are the short chain water soluble amino acids

A

Antidiuretic hormone

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9
Q

what are the long chain water soluble amino acids

A

insulin

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10
Q

how do hormones influence their target cells

A

chemically binding to specific protein receptors

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11
Q

what part of the brain controls the endocrine system

A

hypothalamus

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12
Q

how many hormones does the hypothalamus secrete

A

9

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13
Q

how many hormones does the pituitary gland secrete

A

7

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14
Q

what is the master gland of the body

A

pituitary gland

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15
Q

what stalk like structure attaches the pituitary gland to the hypothalamus

A

Infundibulum

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16
Q

within the infundubulum what are the blood vessels that connect capillaries in the hypothalamus to capillaries in the anterior pituitary

A

hypophyseal portal veins

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17
Q

what are the hormones secreted by the hypothalamus

A

GNRH - Gonadotropin releasing hormone

GHRH - Growth Hormone releasing hormone

GHIH - Growth hormone inhibiting hormone

TRH - Thyroid releasing hormone

PRH - prolactin releasing hormone

PIH - Prolactin inhibiting hormone

CRH - Corticotropin releasing hormone

ADH - Corticotropin releasing hormone

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18
Q

the pituitary gland is the size of a small grape and has how many lobes

A

2

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19
Q

what are the 2 lobes of the pituitary gland

A

anterior pituitary

posterior pituitary

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20
Q

both lobes of the pituitary rest where

A

hypophyseal fossa

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21
Q

the hypophseal fossa is a cup shaped depression in what bone

A

sphenoid bone

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22
Q

what hormone stimulates an endocrine gland to grow and secrete its hormones

A

Tropic hormones

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23
Q

IGF are mainly secreted by what

A

liver

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24
Q

hGH stimulates protine synthesis to help maintain and promote what

A

maintain muscle and bone mass

promote healing and tissue repair

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25
hGH concentration in the blood is maintained by what type of feedback loop
negative
26
what are the hormones of the anterior pituitary
hGH TSH FSH LH PRL ACTH MSH
27
the posterior pituitary gland does not synthesize but stores what two hormones
Ocytocin Antidiuretic Hormone 0
28
what is the function of the thyroid gland
run basal metabolic rate
29
the thyroid is a butterfly shaped gland located where
below the larynx
30
the thyroid is composed of left and right lobes on either side of what
trachea
31
what are the spherical sacs that make up most oft he thyroid gland called
thyroid follicles
32
the wall of each follicle consist of cells called follicular cells which produce what 2 thyroid hormones
Thyroxine (T4) Triiodothronine (T3)
33
what increases basal metabolic rate
thyroid hormones
34
what hormones play an important roll in maintenance in normal body temp
thyroid hormones
35
Calcitonin is produced by what cells of the thyroid gland
parafollicular
36
what hormone decreases the level if calcium in the blood by inhibiting the actions of osteroclasts
Calcitonin
37
what are small round masses of glandular tissue that are partially embedded in the posterior surface of the thyroid gland
parathyroid gland
38
within the parathyroid glands are secetory cells called chif cells that release what
patathyroid hormone (PTH)
39
PTH is a major regulator of what blood level elements
calcium Magnesium phosphate
40
what functions does the pancreas have
endoctine and exocrine
41
the endocrine part of the pancreas consist of cluster of cells called what
pancreatic islets or islets of langerhans
42
alpha cells of the pancreatic islets secrete what hormone
glucagon
43
beta cells secrete what hormone
insulin
44
alpha cells that secrete the hormone glucagon are stimulated by what division of the ANS
Sympathetic
45
Beta cells that secrete the hormone insulin are stimulated by what division of the ANS
parasympathetic
46
what is the main action of glucagon
increase blood glucose
47
the main action of insulin
lower blood glucose
48
level of blood glucose controls secretion of glucagon and insulin via what feedback loop
negative
49
insulin promotes the uptake of amino acids into the body cells which increases the synthesis of what
protein and fatty acid
50
there are two adrenal glands that lay atop of what
kidney
51
what are the regions of the adrenal glands
adrenal cortex adrenal medulla
52
the adrenal cortex consist of what 3 zones
zona glmerulosa (outer zone) zona fasciculata (middle zone) Zona reticularis (inner zone)
53
Zona glerulosa releases hormones called what
mineral corticoids
54
what part of the adrenal cortex releases aldosterone
zona glomerulosa (outer zone)
55
the zona fasciculata (middle zone) releases hormones called what
glucocorticoids
56
what part of the adrenal cortex releases cortisol
Zona fasciculata (middle zone)
57
the zona reticularis (inner zone) releases what hormone
androgens (male/female sex hormones)
58
the adrenal medulla consist of what type of cells
sympathetic postganglionic cells of the ANS
59
sympathetic postganglionic cells of the ANS in the adrenal medulla secret specialized hormones called what
catecholamines
60
what are the catecholamines hormones released by the ympathetic postganglionic cells of the ANS in the adrenal medulla
epinephrine norepinephrine
61
aldosetrone does what to Sodium and potassium and blood pressure
increase reabsorption of sodium from urine into blood stimulates excretion of potassium into urine adjust BP and volume and excretion of hydrogen in urine
62
secretion of aldosterone happens in what pathway
renin-angiotensin-aldosterone
63
what are conditions that initiate the renin-angiotensin-aldosterone pathway
dehydration Sodium deficiency hemorrhage ( overall Low BP)
64
lower bp pressure stimulates what organ to secrete the enzyme renin
kidney
65
enzyme renin reaction in the blood promotes the production of what
angiotensin I
66
what converts inactive angiotensin I into the active hormone angiotensis II
Angiotensin covering enzyme
67
what secretes the adrenal cortex to secrete aldosterone
angiotensin II
68
what is the most abundant glucocorticoid
cortisol
69
what are the actions of glucocorticoids
protine breakdown glucose formation breakdown of triglycerides anti innflammatory effects depression of immune response
70
a low blood level of cortisol stimulates neurosecretory cells in the hypothalamus to secrete what
corticotropin releasing hormone
71
a low blood level of cortisol stimulates neurosecretory cells in the hypothalamus to secrete corticotropin releasing hormone to the anterior pituitary where it stimulates
Adrenocorticotropic (ACTH)
72
Adrenocorticotropic (ACTH) stimulates cell of the adrenal cortex to secrete what
cortisol
73
what two hormones augment the flight or flight response
epinephrine norepinephrine
74
what helps the body resist stress
epinephrine norepinephrine
75
the testes produce inhibin via what cells
sertoli cells
76
where is the pineal gland attached to
rood of the third ventricle of the brain, midline
77
what hormone is released by the pineal gland that sets the circadian clock
melatonin
78
as the endocrine system ages and human growth hormone decreases causing
muscle atrophy
79
as the endocrine system ages and thyroid hormones (T3, T4, Calcitonin) decreases causing what
decrease in metabolic rate increase body fat hypothyroidism
80
as the endocrine system ages parathyroid rises causes
fall in calcitonin decrease loss in bone mass (osteoporosis)
81
as the endocrine system ages and insulin is released more slowly in causes
blood glucose levels to increase faster
82
as the endocrine system ages and estrogen decreases cause
ovaries to decrease in size no longer respond to gonadotropins
83
any stimulus that produces a stress response
stressor
84
what is a sequence of bodily changes that can progress through stages
stress response
85
what happens in the first stage of stress response
initial flight or flight response
86
what happens in the second stage of stress response
slower resistance reaction
87
the initial flight response initiated by sympathetic ANS brings huge amounts of what
glucose oxygen
88
the initial stress response initiated by sympathetic ANS reduces the blood flow to the kidneys which promotes what
release of Rennin
89
the second stage of the stress response is initiated by what and causes what type of response
hypothalamic releasing hormone causes longer lasting response
90
what hormones are involved in the resistance reaction to stress response
Corticotropin releasing hormone (CRH) growth hormone releasing hormone (GNRH) Thyrotropin releasing hormone (TRH)
91
what are the 3 stages of stress response
flight-or-flight response resistance reaction exhaustion
92
what stage is described as the resistance stage failing to combat stress
exhaustion
93
prolonged exposure to high levels of cortisol and other resistance hormones cause what
wasting of muscles supression of the immune system ulceration of the GI tract failure of pancreatic beta cells pathologic changes