Structure Flashcards
(28 cards)
Virus particle = infectious particle
Virion
= Protein which coats the genome
Capsid
ultramicroscopic, ss RNA without any protein coat. They
infect plants
Viriod
proteinaceous infectious particles, cause degenerative
diseases in animals.
Prions
- spherical or rod
- extracellular
- infectious
- outside host
Virion
Largest virus
Smallest
Pox
Parvovirus
All viruses have one copy of their
genome (haploid) except
Retrovirus HIV
-;It is an infectious part of virus
• Carry the genetic informations
• Used as a vectors in gene therapy and in recombinant avirulent
virus vaccinations
Genome
– Serotyping in non-enveloped viruses – Are important antigens that stimulate immune system -It is composed of small protein subunits called Capsomers
Capsid
o Transcriptase o Protease o Integrase o RNA polymerase
• Non-structural virion
proteins (enzymes);
Has 5 equilateral triangles at each corner • 20 identical equilateral triangles & 12 vertices • Structural units on faces to give morphological capsomers
Icosahedral
Length controlled by nucleic acid -may be stiff or flexible
Helical
It is lipid or lipoprotein
• It may be covered by glcoprotein spike-like projections
• (haemagglutinin HA and neuraminidase NA in influenza v.)
• It may be partial or complete • It is sensitive to ether due to its lipid content
Envelope
Proteins are—— ,lipids are——
Viral source, host source
Classification of viruses
order - family - subfamily - genus - species - strain/type
Viralis – Viridae - Virinae - Virus
Classification of viruses regarding:
The type of nucleic acid
All DNA viruses are double stranded except
Parvovirus
All DNA viruses are icosahedral except
Poxvirus
All DNA viruses are non-enveloped except
Pox, Herpes & Hepadna viruses
Parvoviradae
Non enveloped ss dna
Poxvirus
Enveloped complex ds dna
Herpes and hepadnaviridae
Enveloped ds dna
Orthomyxoviridae Paramyxov iridae Rhabdoviridae Filoviridae Bunyaviridae Arenaviridae
Enveloped Helical Single stranded -ve sense
RNA
Coronaviridae
Helical Enveloped Single stranded +ve sense
RNA
