structure of DNA and RNA Flashcards

1
Q

what is DNA?

A

the hereditary material in human and almost all other organisms

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2
Q

where is DNA located?

A

most in the cell nucleus but some is found in the mitochondria

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3
Q

how is the information in DNA stored?

A

in codes

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4
Q

what are the four chemical bases?

A

-adenine (A)
-guanine (G)
-cytosine (C)
-thymine (T)

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5
Q

what bases pair up with each other?

A

A and T
C and G

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6
Q

what are the pairs called?

A

base pairs

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7
Q

each base is also attached to a what and a what?

A

a sugar molecule and a phosphate molecule

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8
Q

together, a base, sugar and phosphate are called a what?

A

nucleotide

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9
Q

how are nucleotides arranged?

A

in two long strands that form a spiral called a double helix, base pairs form horizontal rungs, the sugar and phosphate molecules form the vertical side pieces

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10
Q

what is an important property of DNA?

A

that it can replicate/make copies of itself

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11
Q

each strand of DNA in the double helix can serve as a pattern for duplicating the sequence of bases, this is critical when cells divide because…

A

because each new cell needs to have an exact copy of the DNA present in the old cell

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12
Q

what three components are nucleotides made up of?

A

-deoxynbase
-phosphate group
-nitogen containing organic base

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13
Q

what is a deoxynbase?

A

a pentose sugar, has 5 carbon atoms

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14
Q

how are nucleotides formed?

A

by a condensation reaction between their three component parts (a mono nucleotide)

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15
Q

what is RNA?

A

contains the sugar ribose (another pentose)

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16
Q

what is DNA made up of?

A

two polynucleotide strand joined together by hydrogen bonds formed between the bases on each nucleotide

17
Q

adenine and thymine always join together using what?

A

two hydrogen bonds

18
Q

cytosine and guanine alway join together using what?

A

three hydrogen bonds

19
Q

what are the two distinct ends of a polypeptide chain?

A

three prime end (3’)
five prime end (5’)

20
Q

each base pair is how long apart?

21
Q

what is a phosphdiester bon?

A

a bond between a sugar group and a phosphate group

22
Q

what is a polypeptide chain?

A

a string of amino acids connected together by peptide bonds

23
Q

what are deoxyribose molecules?

A

a pentose (5 carbon sugar) biological molecule

24
Q

what is a phosphate group?

A

a functional group characterised by a phosphorus atom bonded to four oxygen atoms (three single bonds and one double bond)

25
what is a cistron?
a sequence of bases that is the equivalent to one gene
26
what is a locus?
on a molecule of DNA each particular gene (cistron) occupies a specific position
27
what are alleles?
different forms of the same genes
28
what is RNA?
a similar material to DNA, it is made up of a pentose sugar, a phosphate group and one of four bases. the RNA bases are slightly different from DNA which has uracil instead of thymine
29
what is uracil?
uracil bonds to adenine in the same way that thymine does in DNA. Unlike DNA, RNA is just single polynucleotide strand
30
what is messenger RNA (mRNA) responsible for?
transcription
31
what happens during transcription? and what happens during the process?
the DNA helix splits and unwinds, the process is catalysed by the enzyme RNA polymerase
32
what is a polynucleotide?
a combination of nucleotide monomers which are connected to each other through covalent bonds
33
what are introns?
non coding regions of the gene that do not contain codons needed to make the final protein AND are found between exons
34
what is splicing?
biological process where a newly synthesised pre-mRNA is transformed into a mature mRNA OR in splicing, some sections of RNA transcript (introns) are removed and the remaining sections (exons) are stuck back together
35
what are exons?
a sequence of DNA that codes for an amino acid sequence.
36
what is mRNA?
a type of RNA molecule that carries the genetic information from DNA to the ribosome, where it is used to make proteins
37
the mature mRNA molecule then exits the nucleus and is transported to a what?
ribosome
38
the mRNA then combines with the ribosome, here it directs the the next process in what?
polypeptide synthesis translation