structure of nucleotides Flashcards

1
Q

define purine

A

a double ringed organic nitrogenous base
(adenine, guanine)

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2
Q

define pyramidine

A

a single-ringed organic nitrogenous base
(thymine, cytosine, uracil)

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3
Q

define tRNA

A

transfer RNA
a clover leaf-shaped single RNA strand which transfers specific amino acids to a ribosome in translation

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4
Q

define mRNA

A

messenger RNA
a single stranded RNA molecule which is a copy of one gene formed in transcription

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5
Q

define rRNA

A

ribosomal RNA
makes up a ribosome (along with some protein)

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6
Q

define universal energy currency

A

ATP is described as this because it provides energy for many metabolic reactions in all living organisms

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7
Q

define ATP synthase

A

the enzyme that synthesises ATP

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8
Q

define ATPase

A

the enzyme that hydrolyses ATP

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9
Q

define exergeonic

A

a reaction that releases free energy

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10
Q

define endergonic

A

a reaction that requires energy

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11
Q

what does DNA stand for?

A

deoxyribose nucleic acid

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12
Q

what are nucleotides composed of?

A
  • phosphate group
  • a pentose sugar (deoxyribose sugar or ribose sugar)
  • organic nitrogenous base
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13
Q

what are the two type of organic nitrogenous bases?

A
  • pyramidine
  • purine
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14
Q

what bases are pyramidine and what bases are purine?

A

purine : adenine, guanine
pyramidine : cytosine, thymine, uracil

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15
Q

describe pyrimidine

A

single ring

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16
Q

describe purine

A

double ring

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17
Q

what are the functions of DNA?

A
  • it carries the genetic code for protein synthesis
  • it replicates in dividing cells
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18
Q

why is DNA said to be anti-parallel?

A

the two DNA strands run in opposite directions

19
Q

if the strand finishes on the fifth carbon atom, what is it called?

A

5 prime end

20
Q

what do the two sugar-phosphate ‘backbones’ do?

A

protect the genetic information stored within the sequence of bases which face each other within the double helix.

21
Q

what bond holds the bases together?

A

hydrogen bonds

22
Q

what bases pair together?

A

guanine and cytosine
adenine and thymine

23
Q

what doe RNA stand for?

A

ribose nucleic acid

24
Q

describe RNA

A

a short-lived molecule
found mainly in the cytoplasm of the cell - also found in the nucleus
single stranded polynucleotide

25
what are the four organic nitrogenous bases in RNA?
- adenine - guanine - cytosine - uracil
26
in what process is RNA involved in?
protein synthesis
27
what are the 3 types of RNA?
- mRNA - tRNA - rRNA
28
what is mRNA?
single stranded molecule that carries the genetic code for a specific protein from DNA in the nucleus to ribosomes in the cytoplasm
29
what is tRNA?
this transfers specific amino acids to the ribosome A single RNA strand forms a clover-leaf shape held together by hydrogen-bonds between certain base pairs
30
what is rRNA?
this, together with protein, forms a large complex molecule : a ribosome. ribosomes translate the genetic code and join amino acids together to form polypeptides
31
state the differences between DNA and RNA?
DNA - deoxyribose sugar RNA - ribose sugar DNA - adenine, guanine,cytosine, thymine RNA - adenine, guanine, cytosine, uracil DNA - double stranded RNA - single stranded DNA - longer in length RNA - shorter in length
32
where is DNA is found?
the nucleus bound to histone protein
33
what is protein synthesis?
a sequence of DNA nucleotides codes for the sequence of amino acids in one polypepetide chain
34
in how many stages does protein synthesis occur, and what are these stages called?
two stages 1. transcription 2. translation
35
describe transcription
- occurs in nucleus - DNA is read by enzymes and is used to make single stranded mRNA. - this leaves the nucleus through a nuclear pore - this travels to a ribosome in the cytoplasm or rough endoplasmic reticulum
36
describe translation
- occurs at a ribosome - mRNA attatches to the ribosome, and a tRNA molecule brings a specific amino acid - ribosomal enzyme catalyse the formation of peptide bonds adjacent amino acid to form the primary structure of a new polypeptide
37
what does ATP stand for?
adenine triphosphate
38
what is ATP composed of?
- three phosphate groups - a ribose sugar - the nitrogenous base adenine
39
what is ATP described as and why?
energy currency BECAUSE... it is a source of energy for many metabolic reactions in all living organisms
40
what are some uses of ATP?
- muscle contraction for movement - synthesis of complex molecules (e.g protein, DNA) - active transport - nerve impulse transmission
41
how is ATP formed?
the enzyme ATP synthase combines ADP and P i in a condensation reaction this is a endergonic reaction the addition of this phosphate to ADP is called phosphorylation
42
how is ATP broken down?
the enzyme ATPase hydrolyses the terminal phosphate bond releasing a small packet of energy in an exergonic reaction. this forms ADP and P i
43
what are the advantages of using ATP as an intermediate in providing energy, compared with using glucose directly?
ATP - only one enzyme needed to release energy through the breaking of one high energy bond GLUCOSE - many enzymes needed to release energy ATP - releases small packets of energy (30.6kJ) where it is needed GLUCOSE - releases large quantities of energy that may not be needed, generating lots of heat ATP - common source of energy for different chemical reactions GLUCOSE - only releases energy through respiration ATP - easily transported across membrane GLUCOSE - requires a specific carrier protein for transport across membrane
44
what does tRNA consist of ?
hydrogen bonds amino acid attachment site anti-codon